Nervous System Infections

Progressive paralysis is a severe consequence of syphilis of the brain

click fraud protection

brain damage Progressive paralysis( paralytic dementia, Beyle's disease) is an organic nature of the pathology, marked by progressive disorders in psychological and neurological activity, up to the onset of dementia. All processes can be accompanied by somatic and neurological disorders.

The probability of developing a progressive paralysis in a patient varies from 1% to 5% of all people who have suffered syphilis. In addition, the male part of the patients suffers from the disease more often - according to statistics, 5 times than women. The very same incubation period of pathology is 10-15 years from the time of infection.

The reason for the development of this disease is precisely syphilis. At the same time, risks can increase with the development of other sexually transmitted diseases and theology, for example, gonorrhea.

Stages of

pathology In its current Beyle's disease, there are 3 stages, namely:

  1. The initial - its duration varies from 2 months to 6 months. At this stage, patients will complain of a decline in strength and bad sleep, lethargy and dementia, they show themselves with bouts of sentimentality and excessive sleepiness during the day and insomnia during the night. In the process of examination and diagnosis of this stage, doctors check the blood reaction according to the Wasserman method, which in the presence of pathology will be positive. The Lanta reaction is also carried out, and the level of protein in the blood is increased.
    insta story viewer
    progressive paralysis
  2. Stage of full development of .At this stage, patients behave inadequately, lose their sense of tact, are replaced by a sense of euphoria and complacency, delusions inherent in their essence, unreasonable joy or tears develop. The patient has disorders that affect speech and handwriting, some may rapidly lose weight, others may develop a certain degree of obesity, face swells, and the skin turgor changes. Abscesses and damage to the body by boils, excessive bone fragility, degenerative lesions of the heart and liver can develop. The flow of this stage is diagnosed through the Wasserman blood reaction - the results will be positive, like other serological studies.
  3. Dementia - at this stage of the disease the patient has a decrease in self-criticism and weakening of one's own judgments, inferences - ridiculous and delusional, sometimes replaced by a feeling and state of euphoria. As the pathology progresses, the patient will lose interest in the world around him, will not react to external stimuli and answer questions, urinary incontinence and feces develop. At this stage of the patient's limb can be covered with ulcers, strokes can lead to death, brittle bone - increases at times, and can develop atypical, progressing in nature paralysis.

Clinical forms of progressive paralysis

Each of the presented forms of the disease is marked by its special, clinical form of pathology and it is on this issue that it is worthwhile to consider in more detail:

  1. Simple form of - at this stage, the pathology is marked by a characteristic increase in such a sign as dementia, accompanied by certain carelessness, inadequate actions, loss of tact, indifference to the environment and situation, a decrease in the ability to remember, memory loss is observed.
  2. Expansive - this form is characterized by the fact that the patient has a heightened mood and ridiculous ideas, verbosity and megalomania of grandeur.
  3. Depressive-hypochondriacal manifestation of pathology - this stage is marked by depression and attacks of tearfulness, complaints of hypochondriac and Kotar syndrome.
  4. Agitated manifestation of syndrome - in this case there is pronounced motor excitability and propensity of dementia and psychosis patient to destruction, manifestations of attacks of aggression. But the most important thing is hallucinations, affecting hearing and sight.
  5. Circular manifestation of the pathology - when diagnosing this form of the disease, the patient manifests manic attacks and depression, replaceable fits of lethargy and euphoria, inactivity, which is replaced by a moody and gloomy mood that gives way to a feeling of dysphoria.
  6. The hallucinatory-paranoid manifestation of pathology - at this stage the true manifestations of hallucination are noted, little and little systematized, quite a lot of crazy ideas in such interrelation as idea and effect, catatonic disorder itself.
  7. The catatonic appearance of the pathological course of the disease is marked in its manifestation with a so-called catatonic stupor, a certain degree of inhibition or excitation. They, in the opinion of some psychologists, are very unfavorable signs.
  8. Galloping, as well as slowly flowing forms of the disease .Speaking of a galloping form, it is marked by a very rapid course when the patient expresses active motor excitement, delusions and epileptic seizures, vegetative, as well as the trophic nature of the disorder, severe exhaustion and, in some cases, death. The pathological stage can last from 1-2 weeks to several months. If we talk about the slow current stage - it is an atypical form of the course of progressive paralysis. This pathological change is very rare and manifests itself as aphasic disorders and manifestations of apraxia.
  9. Astral paralysis - this symptom and form of pathology is most often diagnosed in patients of the age group for 60 years or more and is characterized by a very long course, on the order of 35-40 years, and as a result lethal outcome. This phase is very similar to manifestations of senile psychosis.
  10. Children's and youthful paralysis - is most often diagnosed in children and adolescents of the age group from 6 to 16 years. The cause of the development of this form of pathology is the infection of the fetus through the placenta of the fetus from the mother by syphilis - the so-called congenital pathology. Most often the disease manifests itself as a delay in the mental development of the child, as well as damage to the inner ear and deformation of the front teeth, seizures of epilepsy.
  11. Taborparich - in this case we are talking about a combination of a progressive form of paralysis and dorsal dryness. Symptoms of this pathology manifest themselves in the absence of knee and achilles reflexes, loss of sensitivity, and depression and nihilistic delirium are observed less often. Symptomatics can manifest itself and a sharp loss in weight or a sharp increase in weight, a manifestation on the face of puffiness, the face turgor changes, the appearance of abscesses and boils, excessive brittle bone.

Symptoms of pathology

Symptoms of progressive paralysis, will manifest itself by such signs:

  • speech impairment and failure in the ability to associate complex words;
  • a patient with a diagnosis of progressive paralysis loses the ability of an elementary account, it reduces motivation several times;
  • patient's consciousness is clouded;
  • memory is lost - both short-term and long-term view;
  • in the upper and lower extremities is observed muscular atrophy and weakness, as well as weakness in other parts of the body;
  • attacks of delirium and hallucinations, increased attacks of irritability and short temper, which are replaced by bouts of depression and moodiness;
  • muscle cramp.

Complex of medical measures

Ceftriaxone The process of treatment is reduced, in most cases, to the course of taking antibiotics and, accordingly, to combat the underlying cause that triggered the course of the disease.

To date, effective treatment of progressive paralysis with Penicillin and its containing preparations. In the case of individual intolerance or allergies to Penicillin - apply Ceftriaxone, which is administered intramuscularly or in a vein for 2-3 weeks. The repeated, control course of treatment, in the absence of deterioration of the patient is shown every 1-2 years.

Most often, the course of treatment takes place in a psychiatric hospital when, in addition to the course of taking antibiotics, a course of pyrotherapy, treatment with leeches, and drugs that suppress the malaria agent is prescribed.

In this case, most often appointed quinine or other antimalarial drugs, as well as compounds, for example 2% sulfur solutions. In addition, Pyrogenal is prescribed - it is injected, intramuscularly, at a dosage of 10 and up to 30 μg, gradually increasing to 80 - 150 μg. The course of treatment is from 8 to 12 injections at intervals of 1 to 3 days.

After the course of pyrotherapy, physicians prescribe a combined course of a specific nature and focus of treatment with Neurosyphilis using Penicillin, Bioquinol, Novarsenol.

After half a year or a year, physicians can prescribe a course of infection, as well as specific therapy, as well as a control study of cerebrospinal fluid and blood. In the absence of positive dynamics of treatment - doctors recommend changing the infectious course of treatment, using a different pyrogenic medication.

In the absence of timely diagnosis and treatment - a patient develops a disability, and also increases the risk of developing other, infectious theology of disease. There may be persistent incapacity, failure in communicability and getting injuries due to falling, convulsions.

  • Share
Meningitis is a serious illness with severe consequences and complications
Nervous System Infections

Meningitis is a serious illness with severe consequences and complications

Meningitis is an acute infectious disease of an inflammatory nature, in which the membranes of the brain and spinal cord are affected. The di...

Meningitis does not spare either adults or children: symptoms, causes and treatment
Nervous System Infections

Meningitis does not spare either adults or children: symptoms, causes and treatment

Meningitis is an inflammatory disease of the membranes of the brain and / or spinal cord. It should not be confused with the inflammation of the...

How infectious meningitis is transmitted: symptoms and treatment
Nervous System Infections

How infectious meningitis is transmitted: symptoms and treatment

Infectious meningitis is a serious bacterial disease with a mortality rate of 10%.The cause of its development in older children and adults are ...