Treatment of gout with medicines: pills, ointments and other drugs

Gout - is a disease caused by a violation of the purine exchange of , resulting in the deposition of urate( uric acid salts) in the joints, ear cartilage, epiphyses of the bones with the subsequent development of aseptic inflammation.

Treatment of disease

Treatment of gout with medicines requires an individual approach aimed not only at fighting this disease, but also withconcomitant diseases. The basis of treatment is the removal of pain syndrome, the prevention of new seizures, as well as complications of a chronic nature that include kidney damage and joint destruction.

Therapy includes taking medication and diet food. Treatment is carried out in 2 stages :

1. Coping an attack at the time of exacerbation.
2. Basic Therapy.

How is the seizure carried out?

During the exacerbation the patient should arrive at the hospital in special hospital departments.

The goal of this stage of treatment of is the removal of pain, a reduction in the joints of the inflammatory process that affects the exchange of uric acid and the restoration of normal mobility of the joint.

For this purpose, the following drug groups are assigned.

NSAID - the more effective medicines of this group are:

• Butadione ( ointment from gout) is an anti-inflammatory, analgesic, antipyretic and antirheumatic. It is applied around the affected area with a thin layer and does not require rubbing;
• Indomethacin ( tablets) is one of the effective anti-inflammatory drugs for treating gout. Has a pronounced analgesic activity. The daily dose of 150 mg is 0.05 g / 3 r./day;
• Ibuprofen ( tablets) - this medicine for gout is used primarily at the altitude of a gouty attack. The daily rate of these tablets from gout is from 1200 to 2400 mg.

Steroid hormones - preparations of this group are very powerful, but contain many side effects. They are prescribed a short course or once in the form of injections, which do directly into the damaged joint, as a result of which the attack can be stopped, and the inflammatory process goes on decline. Basically appointed:

• Betamethasone is a hormonal drug for topical and systemic use( glucocorticoid).
• Methylprednisolone is a drug that can be used in the form of tablets, ointments and injection solutions.

Colchicine -gout medication derived from a cesspool is a powerful medicine that suppresses gout. Produced in tablets - 0.5 mg for taking inside and in ampoules for injections. Its intravenous administration is indicated in severe attacks.

The mechanism of action lies in the suspension of the process of lysosomal degeneration , suppression of leukocytes, obstruction of urate phagocytosis. In addition, the drug has a slight anti-inflammatory, antinininovoe, antihistamine action.

Therapy with colchicine should be started in the prodromal period. After the first reception, improvement is observed after 12 hours. The drug shows its effectiveness in 90% of cases, with timely treatment. The inflammatory process disappears within 48 hours. Lack of effect is observed after its late use.

Basic Therapy

This treatment is treated after the inflammation is removed. The goal of therapy is the recovery of the body as a whole. Treatment is carried out with the help of drugs that are part of 2 large groups:

1. Urinary depressants;
2. Urikozuric means.

Drugs from gout are groups that affect the main link of pathogenesis - lower in the blood level of uric acid , as well as its salts.

The most common urinary depressants are:

• Allopurinol ( tablets) - taken once a day, at a dose of 300 mg, after a meal.
• Hepatocatalase ( injection) - the drug is administered intramuscularly 2-3 r. / Week.
• Thiopurinol - appoint 3 r./day, inside by 0.1 g. The effect is visible even after as many days from the beginning of reception. It normalizes the concentration of uric acid in the blood plasma.

The most popular uricosuric agents are:

• Benzbromarone ( micronized powder) - suppresses the synthesis of purines. The average dose of admission is 100 mg / day;
• Probenecid ( tablets) - enhances the excretion of uric acid. During the first month of treatment, the drug is taken 2 r / day at a dose of 250 mg. If the effect is not achieved, the dose should be brought to 500 mg. / 2 rub. / Day.

Treatment of belated complications

After years, after the initial exacerbation of gout, tofusi , which are mostly painless, can sometimes form, but sometimes increase in size and cause complications. If we timely deal with their treatment, which requires an integrated approach, they will decrease themselves. Sometimes their autopsy can occur independently, without any treatment.

Opened granulomas are treated with antiseptic, for this purpose use iodine-containing agents, antibacterial ointments.

The most severe complication of gout is - chronic renal failure .To avoid this, it is recommended to drink plenty of fluids and periodic intravenous infusions( infusions) of alkaline solutions.

This measure prevents the deposition of urate stones in the pelvis of the liver. For alkalization use sodium infusions, electrolyte solutions, hydrogen carbonate soda. All these funds should be used under close laboratory supervision.

In the process of laboratory tests of urine and blood tests, the presence of acid is estimated, as well as the number of urates excreted in urine. In this regard, at the time of exacerbation, patients should arrive in a hospital setting under the supervision of a rheumatologist.

Auxiliary therapies

Drug treatment of gout will be ineffective if you do not resort to additional measures, which include :

• Physiotherapy;
• Hardware treatment( joint irradiation);
• Heat treatment;
• Massages;
• Hydrotherapy.

The whole range of procedures can be taken in special sanatoriums, where all additional methods of treatment are carried out in the complex.

How to treat joint rheumatism you can learn from our article. Also, the issues of timely diagnosis and prophylaxis are considered. Treating the calcaneal spur with folk remedy is one of the most effective methods of complete cure of the disease. Detailed recipes can be found here.

Dietary food

Nutrition in therapy plays a big role, since individual foods are capable of provoking gout recurrences. From the diet it is necessary to exclude:

In restrictions use:

• Meat of beef and poultry;
• Salt;
• Sugar.

The main menu should include:

• Eggs;
• Fruit juices and herbal teas;
• Honey;
• Fruits and berries;
• Lean fish;
• Cereals and pasta;
• Vegetables;
• Dried fruits, nuts;
• Sour-milk products.

Fat is preferable to use butter and vegetable oil.

Lifestyle for gout

The effectiveness of treatment can be achieved only with complete abandonment of alcohol-containing beverages and limiting consumption of coffee and strong black tea. Without exacerbation, daily warm up and exercise gymnastics.

Video: Principles of Nutrition and Diet for Gout