Korneregel (Kornegel) to the eye. Instructions for use, price, analogs, reviews

Korneregel - a drug to the eye, instructions for use which contains comprehensive information on the composition, indications and contraindications to its use. The medicament is used as part of an integrated or separate treatment of eye diseases.

Excellent therapeutic effect Korneregel due to its following properties:

• successful treatment of corneal dystrophy, inflammation flowing with or without obvious signs of irritation of the mucous membrane body;
• eliminate complications resulting from extended wear contact lenses (also shown to use patients who only pick up their first contact lenses suffer from irritation and hypersensitivity eye);
• erosion control cornea flowing in the acute or chronic form with the signs of relapse;
• keratopathy systematic therapy that develops without inflammatory symptoms;
• acts as an adjunct in the treatment of chemical and thermal burns of the conjunctiva and cornea;
• promotes regeneration of the inflamed and damaged tissues as well as mucosal organ of vision;
• It is used in the treatment of infectious, viral and fungal diseases of the organ of vision;
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• accelerates the healing of eye tissue in the event of mechanical damage resulting from falling, injuries previously Moved surgery, which took place with complications, or else there had been a bacterial inflammation the cornea.

Complex action Korneregel drug provides rapid healing of damaged tissue, reduces inflammation of body mucosa. Depending on the type of disease that has affected the eyeball, the medicament can be used in as a means for monotherapy or as to serve as an auxiliary element in the general course treatment.

Chemical composition

Korneregel eye - a drug, in which the instructions for use given that its composition It contains only one active substance that provides anti-inflammatory, antibacterial and wound healing Effect.

For better digestibility basestock used adjuvants which enhance the therapeutic properties of the drug. The table below shows the qualitative and quantitative composition Korneregel medicament, and also describes the pharmacological properties of these components.

And aux-active substance atelnye	Properties of the chemical components
Dekspa-ntenol	The main active ingredient of the drug Korneregel. Its mass fraction of 1 g of gel is not less than 50 mg. Dexpanthenol is a substance of a precursor of pantothenic acid. After contact with the mucosa and tissue in the eye, it improves metabolic processes in the body view, relieves swelling, inflammation, increases local immunity and resistance to pathogens microorganisms. During healing of wound surface acts as compensation means saturating the fabric eyeball missing amount of pantothenic acid.
cetrimide	Auxiliary substance which improves the therapeutic properties of dexpanthenol. It provides antiseptic action, which is very important in the treatment of inflammatory processes of bacterial origin.
carbomer	Auxiliary preparation Korneregel component, which acts as a stabilizer and thickener liquid medicament bases. Also have a beneficial effect on irritated and inflamed organ of sight. Soothes mucous membrane of the eyeball, thereby reducing swelling of tissues.
disodium edetate	Excipient Korneregel, which acts as a stabilizer of chemical composition of the medicament. It is based on the disodium salt. It is a safe chemical that does not react with other compounds.
Purified water	It provides a liquid-based preparation. Moistens the mucous membrane of the eyes, as well as the epithelial tissue of the body.

All active and auxiliary components of a single dosage form Korneregel formula, which allows to successfully fight various eye diseases.

In what form is available

Korneregel eye, instruction manual which contains detailed information on the procedure of receiving the drug, comes in the form of a gel. The drug is completely transparent with no clearly defined shades. It has no specific odor.

A high degree of density and viscosity. Upon contact with epithelial skin surface texture becomes less thick gel that improves the absorption of the active ingredients of the medicament in the eyeball tissues.

Korneregel packed in aluminum tubes with capacity of 5 and '10 Additional packing box is made of cardboard. The average cost of a drug's retail pharmacy chains ranging from 345 to 360 rubles., But may vary depending on the price leadership policy.

Farmodinamika

Korneregel eye, instructions for use which displays the therapeutic properties of the drug, is a potent ophthalmic agent.

Dexpanthenol, which is an active substance of the drug, getting on the mucous membrane of the eyeball, penetrates quickly into its tissue, enters the bloodstream and lymphatic fluid. It is a biologically active component, which is a positive effect on metabolic processes in the organ of vision.

Under the influence of Korneregel increases fibroblast proliferation, are beneficial conditions for the regeneration of damaged tissues. Viscous gel base allows the effect of enveloping the entire surface of the eye mucosa.

This property of the drug prolongs the action of its main and auxiliary substances which accelerate the recovery process of damaged tissues, removal of inflammation and swelling.

Maximum concentration Korneregel components is achieved after 1 hour after application of the drug to the surface of the eyeball. After completion of the half-main and auxiliary substances medicament, they excreted in the urine of the patient.

Chemical constituents of the drug does not accumulate in the liver tissues do not reduce the filtration of healthy kidney function.

Pharmacokinetics

Active substance formulation Korneregel - dexpanthenol has the ability to be absorbed into the ocular tissues Apple not only through the mucous membranes of the body, but also penetrates into the patient's body through the skin veils.

This distinctive feature of the pharmacokinetic properties of the drug is especially useful when placed on the epithelial tissues of the century. The duration of the therapeutic effect of dexpanthenol solution corneal surface of the eye, is provided excipient - carbomer.

The latter component has a high molecular weight, which does not allow it to penetrate the body tissue of view, and also to saturate the bloodstream and lymphatic fluid. Despite this carbomer acts locally, soothing inflamed mucous membrane of the eyeball, improve the therapeutic properties of dexpanthenol.

application

Korneregel eye, instruction manual which contains detailed information about the order of use of medication is an effective and safe drug. The ophthalmic preparation is indicated for systemic therapy for patients of all age groups. Restrictions on the use of the drug can only be a particular organ of the disease.

For children up to 18 years

Patients pediatric age group undergo therapy with Korneregel after reaching 3 years. The medicament is applied topically. To achieve a positive therapeutic effect is sufficient to make Korneregel 1 drop 3-4 times a day. The average duration of treatment is 10 days, but it depends on the type of ophthalmic diseases.

Final dosage should be adjusted children's eye doctor, who observed the child. In the case of therapeutic necessity, a slight excess of the indicated dose.

Each drop formulation applied directly to the surface of the conjunctival sac of the eyeball, which has symptoms of the disease and requires an anti-inflammatory, antibacterial and wound healing treatment.

adult

Korneregel eye, instruction manual which explains the rules of the use of the drug, is indicated for the treatment of adult patients age group. The medicament is applied to the conjunctiva of the eye 4 times a day at the same time that the body tissue of the patient is maintained a sufficient concentration of the active substance formulation. For 10 min. before bedtime Korneregel paid 5 times.

A single dose ophthalmic agents should not be more than 1 drop. In the process of introducing the drug into the eyeball is necessary to ensure that the tube does not touch the edge of the body mucosa of view. Special opening of the tube makes it possible to make drug drops, without exceeding the recommended dosage instructions.

Duration of treatment is determined individually ophthalmologist, but on average lasts for at least 7-10 days. Severe trauma and inflammatory processes of cornea may require a longer course of treatment.

For pregnant

The manufacturer of the drug has no information on what effect Korneregel has on the developing fetal tissue or the body is already formed child. Clinical drug trials have not been conducted in this area.

Ophthalmologists and gynecologists do not recommend the use of medication for women who are pregnant or carry a newborn baby with breast milk lactation.

This limitation is due to the fact that the active drug substance - dexpanthenol solution capable of overcoming the placental barrier and penetrate into the tissue of the child.

Also, a chemical saturates the mother's milk. Korneregel can be used for the treatment of pregnant or nursing women only if the potential benefit to the health of its higher than expected risk to the child.

for elderly

Patients older age group taking the drug Korneregel in compliance with the same rules and dosage, as well as all other adult patients. The medication is applied to the surface of the conjunctival sac 4 times throughout the day, and the last dose of the drug is introduced just before bedtime.

The regeneration of the corneal tissues in elderly patients is slower due to age-related changes in the tissues of the organ of vision. Therefore, you may need longer therapy Korneregel which takes 7 to 15 days.

During the use of the drug is important to consider the possible presence of other eye diseases which require the use of additional funds for the restoration of visual functions.

Contraindications

Korneregel drug does not contain in its composition hazardous and highly toxic substances that could disrupt internal organs, body cause adverse reactions and contribute to the development of related diseases.

In spite of this drug is contraindicated for use in the following cases:

• idiosyncrasy active medicament or auxiliaries, which manifests itself in the form of a local or extensive allergic reactions;

  

• severe liver and kidney disease, lead to reduction of their filtration function and system failure;
• acute inflammatory eye diseases which require the use of other potent drugs with antiviral, antibacterial or antifungal effect.

All contraindications to the use of a medicament for use in displays Korneregel instructions, but attending ophthalmologist can also detect the pathology of the vision and conditions precluding therapy data drug.

Overdose

In the case of non-compliance with the rules of the dosage of the drug, which is displayed in the manufacturer's instructions, may cause adverse reactions of the body, exhibits the following symptoms:

• decline in the quality of a complete or partial loss of sharpness, focus on subjects as close as 30 meters farther;
• itching and burning sensation of the mucous membrane of the eyeball;
• occurrence of rashes on the epithelial surface of the eyelids and in the conjunctival sac;
• aching or sharp pain in the eye, which is not possible to suppress by accepting tablets analgesics;
• the continued tearing.

All of the above symptoms of drug overdose Korneregel is a local reaction to the use of excessive amounts of the drug. Also available in more serious consequences in the form of nausea, the emergence of feelings of dry mouth, loss of appetite, headache, frustration of a chair.

This body's response indicates that the blood has got a large amount of aqueous solution of dexpanthenol and patient needs in the removal of intoxication.

That, as soon as possible to neutralize the symptoms of overdose and restore Body of normal operation, perform the following steps:

• Rinse patient eye into the cavity which contributes drops medicament using boiled water warm.
• after removal of excess amount Korneregel should gently wipe the circumference of the eyelid and the eyeball with clean, dry towel.
• taken to choose one of the drugs of sorbents in the form of tablets 8 Activated carbon 1 or sachet Atoxil 1 tbsp. l. Enterosgelya.
• take a horizontal position and call an ambulance.

Patients with signs of overdose require Korneregel diagnostic examination and consultation ophthalmologist. In case of pathological changes in the tissues of the eyeball assigned inpatient or outpatient treatment.

Side effects

Ophthalmic formulation Korneregel well tolerated by most patients. Therefore, the probability of side effects is minimal.

Clinical trials of the drug have shown that some patients experience the following atypical reaction of the body:

• conjunctival edema appearance eye bag;
• blurring occurs periodically;
• inadvertent tearing, which is amplified immediately after the introduction of medicament;
• the feeling of having a foreign body in the eye, that provokes a burning sensation and pain, but by visual inspection foreign objects do not exist;
• a red rash on the surface of the century, as well as the epithelial tissue in the circumference of the eyeball;
• sense of incessant itching, covering the mucous membranes of the eyes and the adjacent skin surface.

When side effects should immediately discontinue use of the product, rinse eyes, take sorbent dosage formulation according to that described in the section above, then consult a ophthalmologist.

The doctor will examine the inflamed organ of sight and pick up another drug active ingredients that will not have side effects and local allergic reaction.

Combination with other drugs

There are no research data that could indicate Korneregel incompatibility with other ophthalmic preparations, or other drugs as spectrum.

Manufacturer of gel for eyes in the instructions for use focuses on the fact that during the complex therapy of body ointments and drops with similar properties, Korneregel need to make latest.

This is due to the fact that its adjuvant - carbomer enhances the action of biochemical compounds and solvents. First must be made other eye ointments or drops, but not earlier than after 15 minutes. the surface is applied Korneregel conjunctival sac.

Conditions and terms

To preserve the therapeutic properties of the drug should be stored in a dry and cool place. Do not allow direct sunlight to the surface of the tube and carton packaging medication. ambient air temperature must not be higher than 25 degrees Celsius. Korneregel must be put out of reach of children.

Subject to the above conditions the drug can be stored for 2 years and did not lose its medicinal properties. After the opening of the tube and the beginning of the therapeutic process of medication storage period shall be reduced to 6 weeks.

During this period, the drug must be used or discard it. Do not use the drug, the duration of which storage is greater than the date stated on the packaging.

Conditions of supply of pharmacies

To purchase the product does not require a special prescription from an ophthalmologist or other authorization profile specialist. Implementation of the drug carried out in the retail pharmacy chains.

Reviews

Most patients who undergo the treatment of ophthalmic diseases using Korneregel drug, speak positively about its therapeutic properties. This is due to the fact that the drug in the form of a gel which is in daily use.

Unlike eye drops, has a thick consistency, it does not spread at the time of application to the surface of the body, which facilitates self-therapy in a home. The main component of the gel - dexpanthenol is hypoallergenic, virtually no side effects and other adverse reactions.

Patients who have been treated Korneregel, noted excellent wound-healing properties of the drug. Medication accelerates recovery of corneal tissue process of the eye after her severe injuries, burns, consequences of surgery.

Ophthalmologists also positive about Korneregel using the drug in daily medical practice. The only drawback of the drug is that it is not recommended, as the only remedy for the basis and severe bacterial and fungal infections of the eye. In this case, it will only be effective complex therapy.

analogs

In the pharmaceutical industry there is no other ophthalmic drugs that have a similar chemical composition and the drug formula.

The combination of an aqueous solution of dexpanthenol and carbomer is unique and not repeated in the other Pharmaceuticals external application, which are intended for the treatment of diseases of the cornea and conjunctiva organ of vision.

Korneregel eye - is an effective drug agent that is indicated for systemic treatment of inflammation of the mucosa and tissue of the eyeball. The medicament manufactured by the pharmaceutical company VALEANT in convenient aluminum tubes with capacity of 5 and 10 g, are equipped detailed instructions for use.

Thick and dense consistency of the gel can be used for an independent outpatient therapy. The drug is harmless, does not reduce the efficiency of the kidneys and the liver, systemic therapy is indicated for patients and children older age groups.

Registration of the article: Vladimir the Great

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