Solkoseril ampoules. Instructions for use, price, reviews, analogues

Solcoseryl is a liquid solution in ampoules. Instructions for use refers to the group of medicines to activate cellular processes of regeneration of body tissues. Also, the drug increases the energy balance and corrects some of the phenomena, accompanied by violation of the supply cells with nutrients and oxygen.

Shape and composition of the drug release

The drug appears as therapeutic composition of the solution in dark glass vials with 2 or 5 ml. In 1 ml of 42.5 mg include dialysate from the blood of young bulls-free protein components in the mixture with sterile deionized water. The vials are placed in cartons for 5 or 25 pieces in the contour blister with cells from a polymeric material.

Composition Solcoseryl in ampoules:

Substance	The content in 1 ml, mg
Dialysate blood of healthy calves	42,5
Water for intravenous injection	To 1 ml

Deproteinized dialysate obtained by separating the extract containing blood serum and substances with low molecular weight: amino acids, glycoproteins, nucleotides, and so on. The resulting mixture accelerates metabolism through activation of oxygen transport to all vital organs. A speed increase glucose utilization results in an increase of the internal energy reserves.

The main power unit - a molecule of ATP, adenosine triphosphate. It is a source of energy for all living organisms. ATP is necessary for synthesis of complex biological substances for transport of molecules through the membrane cells of all contractions of the muscle fibers and creating transmembrane energy potential.

Thus, Solkoseril indirectly stimulates many reactions in the body in the initial stages. The drug is manufactured by Meda Pharmaceuticals Switzerland GmbH.

FarmGruppa:

• Metaboliki;
• antihypoxants and antioxidants;
• Organotropona means;
• cardiovascular agents;
• regenerates and reparants.

pharmacological properties

Solkoseril (ampoules) instruction manual recommends that you use to stimulate the growth of new cells and normalization of metabolic reactions. The entire scope of application is very wide. Solkoseril has a positive effect on all bodily functions. The preparation contains a set of compounds with a molecular weight up to 5000 Daltons, the properties of which are only partially investigated to date.

List of key actions Solcoseryl:

• It reduces the oxygen deficiency in the cells;
• increases the phosphorylation activity of enzymes;
• enhances phosphate metabolism - energy sources;
• It accelerates the decomposition of beta-hydroxybutyrate and lactate;
• It increases blood circulation in the tissue and the intensity of the energy-recovery processes.

The medical efficacy of the drug has not been proved because of the lack of traditional research aimed at studying the properties.

The main sales market Solcoseryl - Russia and the CIS countries, which realized about 70% of total production.

Pharmacodynamics and Pharmacokinetics

The pharmacological action after administration of the solution develops after 0.5 hours and reaches maximum activity after 180 minutes on average. Aktovegin increases ATP content, ADP, phosphocreatine, glutamate, aspartate and gammaaminomaslyanoy acid.

The pharmacokinetics has not been studied for the reason that the molecules in the composition of funds can not be separated from the other elements that are normally present in the body tissues.

Indications

Solkoseril (ampoules) instruction manual recommends to compensate states for a number of specific conditions:

• metabolic defects in the brain, including the ischemic disease and traumatic brain injury;
• healing of wound surfaces and ulcers, pressure sores and burns;
• regeneration of body tissues after radiotherapy;
• diseases of the veins and arteries in varicose veins, angiopathy, trophic ulcers.

Solcoseryl solution may also be used for infusion into a vein in a mixture with an isotonic NaCl solution for correction of diabetic polyneuropathy. This is a result of diabetes mellitus type I and II, in which under the influence of the oscillations of glucose in the body is damaged nervous system of the patient. progression rate is 40-60%.

Solcoseril increases the cell sensitivity to glucose without affecting the content of insulin in the serum and thus exhibiting antidiabetic activity. It was also carried out work to study in this area with the participation of 127 diabetic women and men. The results confirmed a high therapeutic activity Solokoserila.

Contraindications

Solcoseril in ampoules, as most of all other medicines, can cause specific reactions because of the possibility of individual hypersensitivity.

Contraindications of the instructions for use:

• age group up to 18 years;
• Pregnancy and breast-feeding;
  
• fixed intolerance blood lysates, the compounds of parahydroxybenzoic acid, benzoic acid and simple;
• severe heart failure function;
• water retention in the tissues of the body;
• oliguria or anuria;
• pulmonary edema.

In diabetes Solkoseril should be used with caution. 1 vial contains 7.75 g of dextrose.

At what age is it possible to apply the ampoule Solcoseryl?

Solkoseril (ampoules) instructions for use is not recommended for the treatment of young persons under 18 years of age. In other cases where use of the drug is shown must be coordinated with the attending physician.

Instructions for use, the dosage of the drug

If there is even the slightest risk of an anaphylactic response it is necessary to perform testing before the start of the administration.

Indications, dosage and mode of administration

Ischemic, metabolic and vascular disorders in the brain. The liquid from the ampoule 1 in admixture with 250 mL normotensive NaCl solution or 5% dextrose solution infused into the vein dropwise. For the embodiment bolus Solcoseril mixed 1: 1 with a solvent.

Occlusive vascular pathology periphery stages III-IV. 20 ml of intravenously every day. Duration of therapy lasts months to 1 and depends on the severity of the symptoms in combination with the speed of recovery of functions.

Chronic venous insufficiency with trophic disorders. The drug is administered three times a day for 7 volume of 10 ml. The total course of treatment - no more than 1 month. It determined the severity of symptoms of the main disease and the stage of its progression.

In the presence of defects in skin wound accompanied desirable treatment complexes for external application: Solcoseryl gel or ointment. The gel looks like a dense, homogeneous structure, almost no color and a distinctive aroma of beef broth. Contains 4.15 mg deproteinized dialysate from the blood of calves immature based on the dry active substance.

When topically stimulates the restoration and renewal of tissue structures.

Solkoseril ointment is suitable for use after the formation of granulation tissue on the wound surface. Fats that are part of the means forming the film and promote healing. After application may be a feeling of slight burning. The phenomenon is of short duration and does not require discontinuation of treatment.

Side effects

Of the rare side effects including allergic manifestations, urticaria, and temperature increase. Local manifestations - redness and swelling in the area of ​​administration.

To eliminate the side effects should take antihistamines and track the status during solkoserilom further treatment in time to take action in the case of allergic manifestations of the more powerful response.

Overdose

Currently, cases of overdose of All Forms of Solcoseryl not registered once. However exceed the recommended dosage and frequency of administration is unacceptable.

special instructions

For intravenous treatment method undiluted preparation it should be administered slowly over 3-5 minutes. You should also take special care in cases of excess potassium in the body, impaired renal function and rhythm abnormalities of myocardial contractions from the norm.

Solkoseril not affect the performance of potentially hazardous activities that require maximum speed of reaction and attention, Department of Road Transport and moving machinery.

drug interactions

Solkoseril not be mixed with any other treatment solutions and, especially, with plant extracts in the same syringe. It should also be cautious when combined with potassium drugs kalisberegatmi diuretics and inhibitors of ATP (angiotensin converting enzyme) - by means of high blood pressure.

analogs

When financial difficulties or in the absence of Solcoseryl it can be replaced in pharmacies other equally active agents. It is also allowed to combine therapy with medications based on other effective substances, but provide similar effect on the human body.

aktovegin

The most famous of the analogs are sold in virtually every pharmacy. The composition comprises 0.04 g gemoderivat deproteinized bovine blood. 1 vial contains 10 ml solution with 400 mg of active substance. Produced in sets of 1, 2 or 5 the contour of cellular blisters, each of which is 5 ampoules.

The composition includes NaCl Actovegin in the ionized form, which is a natural blood component. An additional sodium chloride is added and removed from the solution.

Aktovegin improves trophic and metabolic processes in all soft tissue and preserves the nerve fibers from damage, stimulates microcirculation. The preparation also includes inositol phospho-oligosaccharides positively influence the transport and glucose uptake by the cells. This leads to a more efficient exchange of energy and to reduce the accumulation of lactate in the conditions of oxygen deficiency.

meksidol

Analogue Solcoseryl in pharmacological effects on the human body. The active substance used emoxypine 50 mg per 1 vial. Packed in cardboard boxes of 5, 10 or 50 pieces. The drug has anti-hypoxic, nootropic, anksiolicheskoe and anticonvulsant actions. It protects the cell membranes.

Meksidol stimulates the body's resistance to stress and to the impact of many negative factors: shock, hypoxia, ischemia, alcohol poisoning and overdose of antipsychotics. Medications in the compounds succinates biologically related to the organism that causes their high absorption and active influence in many diseases.

Terms, conditions of sale and storage

Solkoseril included in the B list of drugs and shall not require strict prescription from a specialist. However, the uncontrolled use of unacceptably long period. It is necessary to follow the recommendations of the attending physician, and periodically evaluate the state of instrumental methods of body systems.

The drug must be in the closed area for small children at an ambient temperature of 25 ° C.

Means allowed to keep in the refrigerator, it will not affect the therapeutic properties.

Before introducing the contents of the vial should be warmed to room temperature.

Shelf life - 5 years from date of manufacture. After completion of this period should not be used Solcoseryl.

Overdue vials must be disposed of with household waste in designated areas.

Price in pharmacies

Solkoseril does not apply to the budget. Its average market price - 1500 rubles. 5 vials of 5 ml.

Therefore, prior to use of the drug should be taken to objectively assessing the body condition and the general state of health. But, if necessary, its use will be justified the high cost of treatment with the result.

Solkoseril, like many other drugs in capsules, has a multilateral action. But it is known that the components in the composition of agents are natural and are characterized by high activity. And the instruction manual contains all necessary information for quick and good result.

Registration of the article: Lozinski Oleg

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