Antimicrobial Drugs For Systemic Use

Amoxicillin. Adults with bronchitis, tonsillitis, sinusitis, tonsillitis, flux. Instructions for use

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Amoxicillin - an effective remedy for combating bacterial pathologies. The manual contains the antibiotic dosage for adults and children, duration of therapy, composition and other characteristics of the drug.

The content of the article:

  • 1 Release form and composition of the drug
  • 2 pharmacological properties
  • 3 Pharmacodynamics and Pharmacokinetics
  • 4 Indications
  • 5 Contraindications
  • 6 Instructions for use, the dosage of the drug
    • 6.1 When sinusitis, rhinitis
    • 6.2 bronchitis
    • 6.3 If sore throat
    • 6.4 when the flux
    • 6.5 Skin infections
    • 6.6 In diseases of the gastrointestinal tract
  • 7 Side effects
  • 8 Overdose
  • 9 special instructions
  • 10 drug interactions
  • 11 analogs
  • 12 Terms, conditions of sale and storage
  • 13 Price in drugstores of Moscow, St. Petersburg, regions
  • 14 Videos about the drug Amoxicillin

Release form and composition of the drug

The basis of a medicament active ingredient acts - amoxicillin trihydrate. Its quantity in the drug depends on the release form.

Examples of auxiliary substances include:

  • lactose monohydrate;
  • potato starch;
  • calcium stearate;
  • talc;
  • magnesium stearate;
  • polysorbate.
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Auxiliaries give medicines will need quality, prolong the storage period.

Amoxicillin. Instructions for use, dosage for adults and children. Price analogues

Means sold in the following forms:

  • powdery mass for insertion into a vein at a dosage of 500, 1000 mg;
  • film-coated tablets - 0.5 and 1 g;
  • dry blend to dilute syrup for children at a dose of 125, 250, 400 mg;
  • tablets which need to be dissolved - in 6 volumes of active compound of 0.125 to 1 g;
  • capsules - 250 mg, and 500;
  • cooked syrup - 150, 250 mg 5 mg liquid;
  • dry blend for intramuscular injections - 500 mg capacity.

pharmacological properties

Medication belongs to a number of antibiotics of a wide action.

The preparation of penicillanic group has bactericidal properties, when receiving die:

  • streptococci;
  • some species of staphylococci;
  • salmonella;
  • E. coli;
  • enterococci.

The medicament in tablet form, and suspensions absorbed from the intestine and after 1-2 hours it is found in body fluids - saliva, tears, mucus of the respiratory organs.

Eating food in no way affect the process of assimilation of the drug, so the patient can take it before eating and after.

Conclusion medication through the kidneys in the urine, so if a person suffers from kidney disease, drug metabolism is significantly delayed.

Pharmacodynamics and Pharmacokinetics

The mechanism of the antibiotic based on the destruction of the bacterial membrane structures when the dangerous malicious agents are in the propagation phase.

Amoxicillin, adult dosage is calculated depending on the type of disease-specific enzymes suppresses cell membrane bacteria called peptidoglycans. As a result, harmful strain die.

The antibiotic has bactericidal properties and kills harmful strains:

  • Aerobic gram-positive organisms - staphylococci, other than those that produce penicillinase, streptococci;
    Amoxicillin. Instructions for use, dosage for adults and children. Price analogues
  • negative aerobic agents - E. coli, gonococci, meningococci, salmonella, shigella.

Medicines, which are based on Amoxicillin, do not kill microorganisms synthesizing penicillinase.

Drug resistance agents:

  • Gram-positive Proteus agents;
  • Enterobacter;
  • viral carriers;
  • rickettsia;
  • Morganella Morgagni;
  • Serratia;
  • mycoplasma;
  • Pseudomonas.

FIELD antimicrobial effects expands when antibiotic combination with clavulanic acid, which is a beta-blocker lactase.

In this reaction increases the activity of the medicament applied to harmful microbes:

  • nokardii;
  • causative agents of melioidosis;
  • lenionella;
  • Bacteroides.

But the bulk of Gram-negative strains showing resistance to the antibiotic.

Indications

The drug is recommended to take at sinusitis, pharyngitis, tonsillitis, upper respiratory pathologies that emerged under the influence of opportunistic environment. For their therapy prescribed tablets for adults or children suspension.

If you can see the ear inflammation with pain - otitis media, do not stop for more than 2 days, the doctor may prescribe Amoxicillin. This antibiotic is often prescribed an audiologist, both children and adults. The drug is prescribed for the appearance of bronchitis and pneumonia. The antibiotic helps to relieve cough, relieve pain and improve overall health.

Amoxicillin copes well with bacterial lesions of the digestive tract:

  • cholecystitis - at indisposition discharged in duet with clavulanic acid;
  • gastritisWhich was formed due helibakter pylori - drink together with metronidazole 4 times a day, 500 mg;
  • enterocolitis;
  • typhoid fever - prescribed a large dose of the drug.
Amoxicillin. Instructions for use, dosage for adults and children. Price analogues
Amoxicillin is used in large quantities in typhoid fever.

Means shown as antimicrobial therapy of the urogenital system. In combination with clavulanic acid takes place in the successful treatment of cystitis and urethritis women men.

When endometritis as complex therapy administered antibiotic. It helps to remove inflammation of the lining of the uterus provoked by the infection. Gonorrhea also can be successfully treated with a large dose of 1 reception or holding a course of therapy. Antibiotic therapeutic course include bacterial lesions of the skin.

Amoxicillin, penicillin contained in, appoint, if an adult is sick pyelonephritis pielitah. Tool will help in the treatment of erysipelas - acute infectious disease, which is triggered by the bacteria group A. The dosage is calculated individually.

With the defeat of impetigo adults and children discharged Amoxiclav. A patient suffering from salmonellosis, appoint treatment with antibiotics. But it will happen in case of aggravation of the disease and a weak immune system. In meningitis, brain affecting mucous membranes, drink medicament in a volume of 6 grams per day.

Contraindications

Means can not be used in the following situations:

  • intolerance main component;
  • Children under - dosing of 500 mg and 1000 mg up to 2 years, up to 1000 mg of 5 years at Hemofarm company Sandoz;
  • high sensitivity to penicillin antibiotics in history;
  • Acute infection is viral.

Some manufacturers list of contraindications is expanding.

Pharmaceutical companies Abba and Sandoz is not recommended to use antibiotics when:

  • Allergies to pollen;
  • bronchial asthma;
    Amoxicillin. Instructions for use, dosage for adults and children. Price analogues
  • allergies in children;
  • malignancies of the lymphatic tissue.

During pregnancy and lactation Amoxicillin should be used with caution and only for doctors discharged. Antibiotics for infectious and inflammatory pathologies provoked by bacteria. If the disease is caused by a viral organisms, medication does not help, so he secretly contraindicated to receive in viral infections.

Instructions for use, the dosage of the drug

It advised to read the dosage for different illnesses and the duration of treatment.

When sinusitis, rhinitis

For adolescents 10 years and older and adults, daily intake should be no more than 1500 ml. This volume is divided into 3 applications - morning, afternoon and evening. If the age of the sick child from 5 to 10 years, that portion is 250 ml 3 times a day.

If the child is under five years old, the use of capsules is prohibited. The medicine helps to effectively cope with the symptoms that accompany a cold. After taking the pill components are absorbed in the small intestine and accumulated in all tissues and body fluids.

bronchitis

Amoxycillin, which is the dosage for adults with prolonged cough is 500 mg 2 times a day, prescribed in the same amount for a teenager 10 years and older with a body weight of 40 kg. If the cough is moved to the advanced forms, the duration of therapy will set the attending physician. But the recommended maximum amount per day is 750-1000 mg in three divided doses.

Child from 5 to 10 years are allowed to drink tablets in a dosage of 250 mg three times a day. If the suspension is administered, then take 5 ml of a similar number of times.

Amoxicillin. Instructions for use, dosage for adults and children. Price analogues

Kid from 2 to 5 years allowed to give 125 mg or 2.5 ml three times per day. Tablets can be enjoyed regardless of food consumption at any time of the day. They are washed down with water or is dissolved in a glass of liquid.

If sore throat

If purulent tonsillitis acquired for, then prescribe the drug frequently, because it is an effective medication with a small list of side effects. Efficacy in pathologies of the throat due to the fact that the disease is triggered by staphylococcus - microbe which is sensitive to amoxicillin components.

Despite the fact that the antibiotic can be enjoyed before or after the meal, when he was appointed pathologies throat after eating. This will help to extend the time of its impact on the inflamed tonsils.

when the flux

Medication for a short time will help to stop the infection, to prevent its further spread throughout the body.

The drug is prescribed in a dose of:

  • teens from 10 years and adults is assigned to 500 mg 3p / day;
  • aged 5 to 10 years take 250 mg of 3 times;
  • infants up to 2 years prescribed individual dose, focusing on body weight, per 1 kg for 20 mg of the antibiotic.
Amoxicillin. Instructions for use, dosage for adults and children. Price analogues

Drinking, tablets and syrups recommended after meal. reception and turning to the doctor if at the time of medication therapy in humans appeared rash, runny nose and eye problems, then immediately stopped.

Skin infections

Antibacterial drug helps to cope with different skin diseases. The duration of treatment is 5-10 days. The dosage is established doctor depending on the nature of the infection and neglected diseases.

In diseases of the gastrointestinal tract

Gastritis tablet taking in pure form, with plenty of water. The dosage is 1.5 g per day. But the patient will be discharged in addition cure "Metronidazole". If the doctor deems it necessary to increase the dose, you can bring up to 2.25 g The volume is divided into 3 doses.

Side effects

If you use drugs can occur the following violations:

  • GIT - diarrhea, goiter, nausea, vomiting reflex;
  • malfunctions in the nervous system, manifested by apathy, confusion thinking, anxiety, irritability, insomnia, dizziness, convulsions;
  • allergy, manifested as a rash, rhinitis, conjunctivitis, angioedema, tooth, carding, redness of the skin;
  • rarely appears pain in the joints, fever, dermatitis;
  • there is an anaphylactic shock in rare cases.

The following undesirable effects were found during the laboratory tests:

  • anemia;
  • heart palpitations;
  • a sharp decrease in neutrophils;
  • reduction of leukocytes;
  • difficulty breathing;
    Amoxicillin. Instructions for use, dosage for adults and children. Price analogues
  • thrush;
  • superinfection.

Overdose

The main manifestation in the use of the excess portion is retching and nausea. diarrhea may also occur, which leads to a violation of water-salt balance in the body. First aid is in cleansing the stomach poisons and toxins used laxatives, acceptance of activated carbon and the water balance in the reduction rate.

special instructions

During childbearing can prescribe medication, provided that the benefits for women is justified, and the risk to your baby is minimal. At the time of breast-feeding is permitted to use Amoxicillin, but then you must stop feeding the child milk.

Before starting therapy course, you must make sure that the patient is not allergic to components of the medication.

Antibiotics and alcohol are incompatible. In the treatment of pills in any case can not drink alcohol. Otherwise, it may severely damaged liver, until a malignant neoplasm. By drinking alcoholic beverages is reduced effectiveness of the antibiotic, disturbed concentration of active ingredient in the blood.

drug interactions

Amoxicillin dosage for adults which is not more than 1000 mg per day, reduces the effect of contraceptives, is taken orally. If the means to combine with bactericidal antibiotics, then a synergy. In combination with bacteriostatic drugs - sulfonamides, tetracyclines, macrolides appears antagonism.

The medicine increases the effect of anticoagulants, holding back the emergence of microbes in the intestine, reduces the synthesis of vitamin K.

Means reducing the work of medicines, in which the clearance is formed PABA. Laxative compositions, glucosamine, antacids retard and reduce the absorption of the antibiotic.

analogs

Amoxicillin dosage for adults which was discussed above, is substitutes. Russian pharmaceutical industry has developed several inexpensive drugs that can compete with the antibiotic.

Domestic drug analogues:

  • Amoxil - a medicine discharge of penicillins are sold in tablet form 250 and 500 mg. The active ingredient is amoxicillin. The drug is contraindicated for a baby younger than 6 years. The price is about 120 rubles for 20 tablets.
    Amoxicillin. Instructions for use, dosage for adults and children. Price analogues
  • Amosin belongs to penicillin, based also is amoxicillin. The cost of the drug is 70 rubles. 10 tablets.
  • Amoksikar made of "biochemist" in capsule form, as a powder for injections, granules, syrup for children. In medicine a similar effect. It often appoints ENT pathologies mild to moderate. The cost ranges from 170 to 330 rubles.

There are import substitutes. They include not only the antibiotic, but the combined substances. Most often they include clavulanic acid. It is this component helps to enhance the action of amoxicillin.

are the best substitutes:

  • flemoksin Soljutab It consists of antibiotic and acid. It is a modern product with a wide impact. Distinctive features - is well tolerated, has few adverse effects. It prescribed to children, pregnant women. Produced in the Netherlands. It can not be called cheap - the price of 400 rubles.
  • amoxiclav It developed in three countries - Switzerland, Slovenia, Austria. It belongs to the group of semi-synthetic means combined. It consists of amoxicillin and acid. It is available in several forms. The drug is expensive flemoksin. It costs more than 500 rubles.

Terms, conditions of sale and storage

Medication kept in a cool place, away from sunlight. Ensure that the child does not have access to it. The optimal temperature ranges from 15 to 25 ° C. The period during which it is possible to use a medicine, is 3 years. After opening suspensions contain it in the refrigerator for 14 days. Released by Dr. discharge.

Price in drugstores of Moscow, St. Petersburg, regions

The cost of the drug depends on the manufacturer and the form of:

Amoxicillin. Instructions for use, dosage for adults and children. Price analogues
City Release form and price
20 tablets of 500 mg 16 250 mg capsules Powder for suspension 250 mg / 5ml
Moscow 85 56 98
St. Petersburg 69 102 101
Smolensk 69 103 102
Orenburg 92 57 102

Amoxicillin great help in various diseases - pathology of throat, rhinitis, acute respiratory viral infection, sore throat, skin dermatitis. It is discharged to adults and children. The dosage is calculated based on the release form of the disease and the patient's age. In preparation, there are analogues in Russia and abroad.

Registration of the article: Lozinski Oleg

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