Pantsef. Instructions for use for children (suspension, tablets, injections). Price, reviews, analogues

Pantsef - a semi-synthetic agent, referring to the antibiotic third generation, with a broad spectrum of action. The antibacterial agent has a bactericidal action to destroy the pathogen in the body. Before use, the drug should be familiar with instructions for use.

release Form

Antibacterial drug pharmaceutical industry produces several varieties:

1. solid dosage form:

• tablets in an oval;
• means enteric-coated;
• the drug has a light cream color;
• the drug is packaged in a plate made of aluminum foil by 5/6 tablet;
• blisters are packaged in a box of pressed paper by 1 or 2 pcs .;

2. granules for suspension:

• spherical grains of yellow;
• drug substance scattered in the dark glass vial, a screw cap made of aluminum, which has a gasket made of polyethylene and the control of the first opening;
• bottle with loose medication packaged in a box made of cardboard;
• inside the enclosed measuring spoon and instructions for use;
• drug off the shelf smells of citrus fruits.

the drug

The composition of the different forms Pantsef preparation includes chemical substances which have a certain influence on the organism:

1. pills:

• trihydrate tsifiksima:

1. exhibits bactericidal effect;

• microcrystalline cellulose:

1. It cleanses the gastro-intestinal tract of toxic substances;
2. normalizes digestion;
3. improves the immune system;
4. reduces the risk of cancer pathologies;

• starch derivative:

1. improves absorption process;

• monobasic calcium phosphate:

1. holds water;
2. exhibits laxative properties;

• sodium dodecylsulfate;
• chemical compound and magnesium salts of stearic acid;
• methylhydroxypropylcellulose;
• glycol polymer;
• amphoteric oxide of tetravalent titanium;

2. slurry:

• 7-aminocephalosporanic acid:

1. damages the cell wall of the smallest organisms;
2. release autolytic enzymes;

• cane carbohydrate:

1. improves the taste of the drug;

• natural polysaccharide:

1. increases the viscosity of the medicament;

• benzoic acid sodium salt:

1. a preservative;

• citrus flavor.

pharmacological properties

Pantsef (instruction manual describes the effect of the drug on the human body) - a semi-synthetic antibacterial agent of the third generation.

Getting inside, the drug exhibits the following properties:

• It inhibits the synthesis of cell membranes of pathogenic microorganisms;
• gives peptidoglycan cell wall formation;
• It exhibits a stability with respect to bacterial enzymes to combat antibiotic;
• detrimental effect on Gram-positive bacteria:

1. Staphylococcus aureus;
2. enterococcus;
3. Pneumococcus;
4. spherical Gram-positive bacteria of the genus Streptococcus;
5. Bacillus subtilis;
6. Enterobacter kloatse;
7. E. coli;
8. atsinetobakter;

   

9. fixed bacteria Pfeiffer;
10. meningococcus;
11. diplococcus gram;
12. Yersinia;
13. asporogenous aerobic gram-negative coccobacilli of the genus Bordetella;
14. bacteroides;
15. Pseudomonas aeruginosa;
16. spiral gram-negative bacterium.

Pharmacokinetics

When ingested, the antibacterial drug undergoes certain changes:

• after ingestion is absorbed to 50% drug, regardless of food consumption;
• means the maximum amount of plasma reached within 6 hours;
• bound to serum proteins by 65%;
• The mean pharmacokinetic parameter in elderly patients is 40% higher than that of other patients;
• half of the drug appears unchanged in urine during the day;
• 10% of the drug excreted in the bile.

Indications

Pharmacological agent with broad spectrum of action prescribed medical specialists of different spheres of medicine:

1. therapy:

• inflammatory lesion of the bronchi;
• infectious pathology of lung tissues;
• accumulation in the pleural exudate of various genesis;
• the defeat of the tonsils;
• painful condition pharyngeal mucosa;

2. urology:

• inflammation of the bladder;
• urethra infections;
• Pathology pyelocaliceal kidney apparatus;
• purulent inflammation of the urinary system;

3. infectology:

• tick-borne Lyme disease;

4. otolaryngology:

• inflammation of the organ of hearing;
• pathology of the paranasal sinuses;

5. surgery:

• necrotic process that develops in the bone and the surrounding soft tissues;
• peritonitis;
• septicemia;
• postoperative prevention of complications;

6. venereology:

• uncomplicated infection provoked by gonococcus;
• chlamydia;

7. neurology:

• inflammation of the membranes of the brain and spinal cord bacterial nature;

8. cardiology:

• Infectious diseases of the endocardium.

Instructions for use

Pantsef (instruction manual provides guidance on the use of medication) - is an antibiotic that is prescribed medical professionals in many pathological processes in the body.

Name of disease	Features of the application and dose
Infections of the lower respiratory tract	1. Tablet form: means must be taken orally; dose should be administered at the rate of 8 mg / kg of patient weight; Tablets need to drink every day; duration of treatment depends on the severity of the pathological process, and is 5-10 days. 2. Suspension: a vial of granules necessary to add 40 ml of warm water; means mix thoroughly; for use of the drug is necessary to use a measuring spoon; use the drug should be 2 times a day - morning and evening, 0.2 g; edinokratnoe may use a daily dose means; treatment determined by a physician specialist.
Inflammation of the urinary system	1. The solid dosage form: medication should be consumed between meals; Tablets need to drink 1 time per day; in severe disease process drug dose should be divided into 2 doses - in the morning and evening; daily quantity of the drug for patients over 12 years of age is 400 mg; duration of treatment - no more than 10 days. 2. The slurry: before applying the medicament must be shaken well; dosing of the drug necessary with measuring cup; means daily amount determined by the attending physician, but not more than 0.4 g of the slurry; week course of treatment.
Chlamydial and gonococcal infection	1. Pills: therapy for uncomplicated genital infections need to apply 400 mg of the antibacterial agent; use the drug should be independent of food intake 1 times a day; on the recommendation of a specialist doctor can use ½ the daily dose in the morning and evening; the duration of treatment is 10 days. 2. Suspension: with simple forms of inflammation should consume 0.4 g of liquid formulation; means you need to drink time / 24 hours; therapy defines a medical specialist.
Pathology of upper parts of the respiratory system	1. The solid dosage form: Patients weighing 50 kg should take 400 mg of medicament; you must use a tablet once a day; if necessary, the daily amount of funds should be divided into 2 reception - morning and evening; the drug should be used regardless of the meal; duration of treatment up to 14 days. 2. Granules for suspension: before use Shake well fluid; means to measure the right amount to be using the measuring spoon; for patients older than 12 years of daily dose is 0.4 g; medication should be consumed once a day; on the recommendation of the attending physician medicine can be drunk in the morning and evening, dividing the daily quantity in half; duration of therapy for 2 weeks.

Pregnancy and lactation

Use an antibacterial agent from the group of penicillins during child bearing is necessary only on the strict medical specialist. Application medicament semisynthetic means during lactation is associated with compulsory termination of breastfeeding.

children

Cephalosporin antibiotic 3rd generation with a broad spectrum of activity should be administered to children. You must know that the tablet form of the drug should be used with 12, and the suspension was allowed to use a six-month-old.

1. The solid dosage form:

• The drug should be used inside, regardless of food consumption;
• means dose for children weighing more than 50 kg is 400 mg 1 time per day;
• duration of treatment depends on the severity of the pathological process and the recommendations of the attending physician.

2. Suspension:

• measure the right amount of drug necessary with measuring cup or spoon;
• the daily amount of medication corresponding to 0.4 g / once a day;
• If necessary dose can be divided into 2 intakes - morning and evening;
• duration of therapy is not more than 14 days.

For newborns

Pantsef can not be used to treat patients who are under 6 months. For children weighing up to 50 kg of the drug should be used only in the form of a slurry.

child's weight	The daily amount of the drug / measuring spoon	The daily dose in g
up to 5.5 kg	2,5	0.05 g
from 5.5 to 12 kg	5	0.1 g
12-24,5 kg	10	0.2 g
from 24.5 kg to 37 kg	15	0.3 g
37-50 kg	15-20	0.3-0.4 g

The drug should be applied at the rate of 0,008 g of a liquid medicament per 1 kg baby weight once a day. The duration of treatment is 10 days, or at the recommendation of the attending physician and depends on the occurrence of the disease process.

When renal impairment

With partial or complete loss of the ability of the kidneys excrete urine must to establish the dose according to creatinine in serum:

• the amount of the final product of the reaction of creatine phosphate from 20 to 60 ml / min - daily requirement of the drug must be reduced by 25%;
• kidney cleansing ability less than 20 ml / min - amount of drug necessary to reduce in half.

In human liver

Instructions for use Pantsef antibacterial agent does not describe the effect of the drug on the hepatobiliary system. Postmarketing study medication for patients with hepatic impairment have not been conducted.

Use in the elderly

Over the life of all human body systems undergo age-related changes, so the use of cephalosporin medication for the elderly must be with extreme caution, constantly monitoring the performance of the kidneys and the system circulation.

Contraindications

Pantsef drug has a number of limitations, which include:

• a history of allergic reactions;
• intolerance of antibiotics penicillin;
• hypersensitivity to the drug;
• outflow of blood from blood vessels;
• inflammation of the small and large intestine in history;
• gestation period of gestation;
• breast-feeding;
• patients up to 6 months.

Side effects

Use of the drug, has an antibacterial effect on the body, may be associated with adverse symptoms:

1. Digestive System:

• a complete lack of appetite;
• dry mouth;
• speeded defecation;
• vomiting reflex;
• pain in the abdomen;
• bloating due to excess accumulation of gases in the intestine;
• elevated liver enzymes;
• increase in bilirubin s blood plasma;
• candidiasis of the gastrointestinal tract;
• microbial imbalance;

2. blood:

• reduction in the number of leucocytes per unit of blood;
• lack of platelets;
• enhanced destruction of erythrocytes;

3. central nervous system:

• unsteadiness;
• migraine;

4. immunity:

• painful irritation of the epidermis;
• urticaria;
• swelling of the skin;
• an increase of eosinophils;
• fever with chills.

Overdose

Pantsef (instruction manual draws attention to the prevention of an excess of the drug in the body) - a drug with bactericidal action. Misuse of the drug can cause an overdose, which manifests increased side effects.

When the first symptoms of excess drug in the body is necessary:

• wash out the stomach;
• drink antihistamine;
• call an ambulance.

There is no antidote. Hemodialysis did not significantly affect the reduction in the amount of antibacterial agent in the body.

special instructions

Before applying cephalosporin agent should be familiar with the special instructions that detailed in the annotations to the drugs:

• do not start using the antibacterial agent without making a test for an allergic reaction;
• when a hypersensitivity discontinue treatment means;
• use of the drug is necessary with lacto bacteria, to reduce the likelihood of dysbiosis;
• during treatment with antibacterial medication should be prescribed vitamins group B.

Compatible with alcohol

The drug has a devastating effect on the bacteria, you should not be used in conjunction with any alcoholic beverages.

Joint use of ethyl alcohol and antibiotic can provoke toxicity in the body, which is characterized by:

• vomiting reflex;
• severe pain in the head;
• facial flushing;
• tachycardia;
• saccadic breathing;
• painful spasms in the limbs.

drug interactions

Pantsef reacts with certain pharmacological agents:

• increased toxic effect on the body while using a loop diuretic agents;
• increased chance of bleeding when combined with antithrombotic medications and NSAIDs;
• antiepileptic drugs increase the concentration of the antibiotic in the blood plasma.

Where can I buy

Germicide can be purchased in the pharmacy network. For the acquisition of the pharmaceutical preparation is necessary to take your doctor written prescription.

Cost of medicament depends upon the shape and varies in the range:

• Tablet kind of drug - 1665-2270 rubles .;
• dry granular material for the preparation of suspension from 1300 rubles. to 1740 rubles.

Storage conditions

Pantsef (instructions for use of the drug makes recommendations on means of saving) - a medication for which you should become familiar with conditions of storage:

1. tablet form:

• save in a dark place;
• preservation temperature must not exceed 25 degrees Celsius;
• store 36 months from the date of manufacture;

2. granules for suspension:

• cooked the drug should be stored out of the reach of children;
• preservation period shall not exceed 2 weeks;
• temperature regime must meet the 14-24 degrees above zero;
• dry agent should be stored 12 months from the date of issue.

analogs

Pharmaceutical industry produces antibacterial agents, which have an effect on the body similar to the drug Pantsef.

The name of the drug	Structure	Features of the application	pharmachologic effect	cost of
Gepatsef combi	tsefaperazon; beta-lactamase inhibitors.	corresponds to an average dose of 2-4 g per day; means should be used every 12 hours; the maximum daily amount of medicament to 8 g; duration of therapy is determined by the attending physician in accordance with the course of the pathological process.	It acts on the sensitive microorganisms; It inhibits the biosynthesis of peptidoglycan; It inhibits bacterial enzymes essential.	from 275 rubles. to 345 rubles.
Auropodoks	adsorbed cefpodoxime ester 3 generations; carboxymethylcellulose; dairy carbohydrate; sodium dodecylsulfate; low molecular weight polyvinyl pyrrolidone; stearic acid, magnesium salt; Medical liquid; amphoteric oxide of tetravalent titanium.	daily quantity of 0.4 g of the drug, which should be divided into 2 doses; use the means necessary during the meal; course of treatment determined by the doctor-specialist individually for each patient.	It inhibits the synthesis of bacterial walls of microorganisms.	from 435 rubles. to 505 rubles.
Evrozidim	vital tsefazidim antibacterial agent; soda ash.	a medicine intended for parenteral administration; drug to use up to 3 times a day, at regular intervals; the average amount of medicament corresponding to 1-6 g / day; duration of treatment recommended by a specialist doctor.	It has a devastating effect on the following microorganisms: Pseudomonas aeruginosa; Klebsiella pneumoniae; Proteus vulgaris; Pseudomonas; Enterobacter; asporogenous bacteria in the form of rods; meningococcus; Haemophilus influenzae; peptostreptokokki; Staphylococcus aureus.	from 3400 rubles. up to 4500 rubles.
Alvobak	cephalosporin antibiotic with broad-spectrum ceftriaxone.	dose depends on the severity of the disease process; the average number of drug - 1-4 g per day; medicament should be used 1 time / 24 h; appoints the course of treatment the physician on the basis of the general state of the organism.	violates the synthesis of murein; characterized by resistance to the action of many beta-lactamases.	from 220 rubles. to 310 rubles.
Ikzyme	cephalosporin cefixime; corn sugar gum; sodium benzoate; silica; sucrose; flavor.	pharmaceutical substance taken orally, regardless of food consumption; Standard treatment for 7 to 14 days; recommended daily amount is 0.4 g; medication should be consumed once / day.	It has a devastating effect on most gram-positive and gram-negative bacteria.	from 195 rubles. to 230 rubles.

Pantsef medicament effective against many prokaryotic microorganisms domain has a devastating effect on the bacteria resistant to penicillin, it is written in the instructions for use medication.

Registration of the article: Vladimir the Great

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