Diffuse Liver changes and pancreas. What is it that is, the types, causes and treatment, diet

Diffuse changes in the liver and pancreas tissues include the group of diseases that are expressed in violation of metabolism within the digestive organ cells (hepatocytes), as well as developing its dystrophy. These are processes which are irreversible and lead to the appearance of liver failure.

What changes diffuse liver and pancreas

Diffuse changes in the cellular structure of the liver and pancreas - it chronic or acute form of hepatosis, which is characterized by the gradual destruction of the cells of the organ.

First, there are such violations are associated with the absence of a full assimilation of nutrients entering the body cells. Then, in developing their structure changes, which lead to an increase in liver tissues.

With the spread of diffuse liver changes, the substitution of healthy hepatocytes in adipose tissue, which is unable to perform the previous function.

The table below displays the severity of this disease, as well as their brief description:

Degree of diffuse liver changes	The current state of body tissues
1 degree	The liver is enlarged, and the survey found that there are signs of healthy replacement hepatocyte adipose tissue.
2 degree	The patient's condition worsens, symptoms start to disturb more often. Besides adipose tissue fibrotic detected compound.
Grade 3	Is the destruction of most of the cells of the liver, cirrhosis, which leads to a failure in the body, and without proper treatment causes death.

Allocate chronic and acute form of the disease. The first type is characterized by changes in diffuse liver inflammation, and absence of recurring symptoms of disease. The acute form of the disease characterized by a dynamic clinical saturated symptoms.

Causes of diffuse changes in the liver and pancreas

Diffuse Liver changes - it is a disease that develops under the influence of negative factors, and related diseases of internal organs.

Identify the following causes of this disease:

• having 3-4 obesity step;
• diabetes, when the patient is already on substitution therapy insulin injections;
• chronic shortage of vitamins and minerals caused by an unbalanced diet or accompanying diseases of the gastrointestinal tract, which violate the digestion;
• Cushing's syndrome;
• insufficient consumption of products containing in its composition of proteins of animal origin (This cause of diffuse changes in the liver is quite common among vegetarians);
• a genetic predisposition to the destruction of hepatocytes;
• alcohol abuse, intake of drugs;
• constant intoxication caused by contact with toxic substances;
• metabolic disorders of biliary acids and bilirubin;
• continuously taking drugs have a toxic effect for hepatocytes;
• predominance food diet high in carbohydrates (bakery, confectionery, products, pastries, cereals porridge);
• low physical activity;
• thyroid diseases that cause hormonal imbalance (nodular goiter, hyperthyroidism, hypothyroidism, myxedema).

In 5% of cases, the fundamental factor of diffuse liver changes favor the regular consumption of too much fatty food. There is a failure in the synthesis of phospholipids, resulting in the deposition of an excessive amount of fat in liver tissues directly.

Effect of the disease on the body

Diffuse changes in the liver - it is a disorder that destabilises the work of the entire digestive system. As soon as there is a replacement of healthy hepatocytes on adipose tissue, or else did occur cell death, gradually manifested clinical picture of the disease.

The liver loses its functionality to provide cleaning the body of toxins, resulting from a metabolic process. As a result, developing appropriate signs of the disease, indicating a change in the tissue structure.

Symptoms changes diffuse liver and pancreas

Regardless of which factor has provoked the development of diffuse liver changes, clinical manifestations of the pathological process is always the same. With the reduction in the number of healthy hepatocytes occurs deterioration of health of the patient, the first signs of liver failure.

The following symptoms may indicate the presence of a person of diffuse changes in the liver:

• fatigue and a feeling of constant fatigue, which is present even after a good rest;
• heaviness in the right hypochondrium;
• bitter taste in the mouth, which occurs despite the fact that people do not eat pungent foods or other foods that have required taste;
• partial or complete loss of appetite;
• disgust for fatty and fried foods;
• nausea and vomitus selection;
• difficulty concentrating, symptoms of confusion;
• rapid weight loss, which is especially pronounced against the backdrop of the refusal to take food;
• appearance of jaundice of the skin and whites of the eyes;
• disorder chair which 90% is expressed as the liquid diarrhea;
• myopia, lowering blood pressure;
• discoloration of feces (during defecation allocated white, gray or completely same biomass which may contain in its structure particles of undigested food);
• the urine becomes cloudy and becomes rich dark brown.

Diffuse changes in the liver - it is a disorder that can be stopped, but this man, find yourself above symptoms should immediately consult a doctor or therapist gastroenterologist. Otherwise, the destruction of the digestive organs will continue until it reaches the stage of cirrhosis.

Diagnosis changes diffuse liver and pancreas

To determine the current changes in the structure of cells, the physician must have complete information about the state of health of the liver.

To do this, the patient is prescribed the passage of the following diagnostic procedures:

• ultrasound - carried out a survey of the entire organ, set its dimensions are determined by liver sections, which are signs of structural changes;
• CT scan - detects the presence of symptoms of liver parenchyma grain, can set the density of adipose tissue and body segments, the functionality of which is now reduced;
• analysis of venous blood - is carried out in order to determine the possible presence of viral microorganisms that infect the liver (hepatitis A, B, C, E) parasitic life forms, as well as set the concentration of enzymes produced by the organ indigestion;
• biopsy - the most accurate type of survey, which allows us to study the liver tissue in the laboratory conditions, make an informed medical opinion about the presence or absence diffuse liver changes, to determine the severity of this disease (introduced through the abdominal wall Selection needle with which the doctor takes fragment hepatic tissue);
• urinalysis and blood capillary, which is taken to an unnamed river finger.

After receiving the diagnostic results of the survey of physician therapeutic regimen aimed at cupping process further diffuse liver changes, and preventing the occurrence of negative consequences.

Throughout the course of treatment the patient will have some more time to take the above types of tests.

Furthermore, the diagnosis of liver tissue is a prerequisite, if the person present the following diseases:

• microalbuminuria;
• violation of metabolism in the body;
• insulin resistance;
• severe abdominal obesity.

This pathology, the presence of which gives normal functioning of liver tissue, which ultimately leads to destruction of hepatocytes, the formation of fat droplets and reduced functional ability of digestive organ.

Prevention changes diffuse liver and pancreas

To prevent the occurrence of diffuse changes in the tissues of the liver, it is necessary to perform simple daily rules aimed at maintaining the health of the body.

Preventive measures include the following actions:

• complete rejection of alcoholic beverages, tobacco products, receiving drugs;
• a balanced diet, eating protein, carbohydrate foods with a minimum fat content (the ratio of these components in each dish should look as follows: - carbohydrate - 60% protein - 25% fat - 15%, which is sufficient for normal liver and all systems organism);
• secure a moderate physical activity to avoid a sedentary and inactive lifestyle (Recommended to do light jogging, hiking after the completion of the working day, bike riding, swimming);
• avoid stressful and conflict situations, to avoid overstimulation of nerve (if this can not be achieved, it is necessary to take a mild sedative in the form of extracts of valerian, tinctures peony, Glycine);
• not to eat fried, smoked, too fatty foods (in food should be a menu that represents the biological value);
• limit contact with household chemical substances, other liquids and vapors that are toxic nature of origin;
• undergo an annual medical examination of the planning, which will allow time to identify potential signs of diffuse liver changes.

Another rule is to conduct preventive gepatoza ordered sexual life. You must have one sexual partner, to prevent occurrence of casual sex, or else use the barrier method. Diffuse changes in the liver may be influenced pathogenic activity of hepatitis C virus, which is sexually transmitted.

Therapies changes diffuse liver and pancreas

Diffuse changes in the liver - it is a violation that requires combined therapy with the use of medication, dietary compliance rules and, in some cases, non-traditional methods medicine.

Medications

Treatment with gepatoza pharmacy medication is the most effective therapy. To quickly achieve a positive result with a minimum of complications, it is recommended to use the following medications:

• Progepar - shown to the reception by adults and children after the age of 12 years, the recommended dose - 2-3 capsules 3 times a day with liquid, drinking plenty of fluids (minimum duration of administration is 4 weeks, and the optimal course of therapy directed the restoration of tissues of liver -. 3 to 4 months, can cause allergic reactions in the lungs as urticaria, itching of skin, and rash);
• Syrepar - injection for intramuscular and intravenous administration, which are shown in cirrhosis, structural changes its tissues, alcohol, chemical and drug intoxication (Administered 1-2 times a day to 3 ml in a breech or vein and common therapy involves saturation of the body medicament 150-200 ml, which is about 3 on the average months. treatment);
• cyanocobalamin - is introduced into the patient with diffuse features changes in the liver by intramuscular injection 1-2 times per day for 10-15 days (the main purpose of the drug - this improved fat metabolism, preventing their deposition in tissues liver);
• choline - 1 patient once a day by intravenous drip give a total volume of 200-300 ml, with 5 ml - this injection of the medicament (Mean duration of treatment is from 7 to 15 days but can be adjusted by the attending physician depending on the severity disease);
• folic acid - taken in powder form of 5 mg daily for 1 month, after 30 days it is recommended to pass the next course of therapy (not being used. for the treatment of diffuse liver changes in children and is not recommended to accept patients who are suffering from inflammatory processes intestine);
• lipoic acid - enters the patient's body by intramuscular injection, which is composed of 4 ml drug (1 per day), the duration of the therapeutic course of 20 to 30 days, and after 1 month. break the regimen was repeated again.

Depending on the clinical picture of this disease, the severity of diffuse changes, the physician may use other drugs. The course of treatment is developed for each patient. In addition, a prerequisite of successful drug therapy is to eliminate the reasons, provoked changes in liver tissues.

Traditional methods

There are alternative methods of treatment of diffuse liver changes, which are based on the use of folk remedies. Here are some of the most effective recipes, that can be used alone to treat the liver, being at home:

• 1 take the small round gourd shape, whose weight is not more than 1.5 kg, cut with its apical portion as in the purification of water-melon, with a spoon and select seeds inside part pulp and then fill to 1 liter of honey from grasses (put in the refrigerator for 24 h infusion, then pour honey pumpkin extract in a glass jar and receive 1 tbsp. l. 3 times a day after meals for 20 days);
• It needs to take 1 tsp. l. Dried medicinal herbs - succession, sage, chamomile, raspberry, lime, birch, yarrow, pour into a thermos, add 1.5 liters of boiling water, close the container with a lid and leave overnight to medicinal plants to give all their nutrients (take 1 cup of broth 3 times a day for 20 minutes. before a meal therapeutic course of 30 days);
• purchased at the pharmacy dried leaves St. John's wort and dandelion, pour them in a metal container, pour 1 liter of tap water, put on a slow fire and boil for 15 min., and the resulting broth to drink 200 ml 3 times a day for 15 min. before meals for 2 months .;
• take 50 g of rosehip berries, 1 tbsp. l. of dried marigold flowers, leaves, valerian, nettle, immortelle, then pour 1.5 liters of boiling water, container tightly wrap a towel and leave overnight for infusion (to drink 250 ml of broth 2 times a day 30 minutes. before eating, and a course of treatment is from 1 to 6 months. depending on the severity of the disease).

The effectiveness of the use of folk remedies treatment is not scientifically confirmed. Therefore, it is recommended to pass a comprehensive examination of the body, the liver tissues themselves directly before applying the above recipe, and to consult with a physician.

diets

Proper nutrition, consumption of foods which contribute to the restoration of damaged liver tissue, allows for enhanced therapeutic effects of drugs.

In the human diet, suffering from diffuse liver changes, you must present the following products:

• vegetable soups;
• sauerkraut;
• Fresh vegetables, herbs and fruits;
• chicken breast, turkey meat, rabbit, steamed;
• boiled potatoes in their skins;
• lean porridge oats, corn, barley, pearl barley;
• grated carrots;
• braised onions with vegetables;
• low-fat dairy products.

Under the categorical prohibition are the following types of beverages and foods:

• all kinds of sausages, canned meat and fish, as well as other products, prepared by the primary processing of meat;
• dishes, containing in the structure of animal fats;
• excess amount of vegetable fat (allowed to use no more than 1 hour per day. l. refined sunflower oil);
• canned vegetables and other dishes prepared with marinade;
• meats of all kinds;
• carbonated drinks;
• confectionery, candy, chocolate;
• beer and spirits.

Compliance with the rules of diet is a prerequisite for the successful treatment of diffuse liver changes. Further use of fatty, marinated, smoked foods, as well as drinking alcohol, will exacerbate the patient's state of health and treatment will not bring positive results.

Other methods

In the event that changes the diffuse liver reached irreversible processes, drug treatment, diet and traditional remedies do not bring the expected results, possible surgery intervention.

Surgical treatment is indicated in cases where a patient diagnosed with cirrhosis or as much of organ replaced by fibrous tissue, is not fulfilling its functions and developed chronic liver failure.

Surgeon performs organ transplant patient. From a compatible donor is taken of the normal liver tissue, and then the transplant. During the 12 months.

Transplanted organ fragment gets normal size at the expense of self-dividing hepatocytes. The operation is performed under general anesthesia in sterile conditions inpatient. rehabilitation periods are from 3 to 6 months.

complications

In the absence of adequate medical treatment, the condition of the liver tissue will slowly deteriorate, which will necessarily impact on the patient's health.

May develop the following complications:

• chronic pancreatitis as well as a healthy pancreas can be only in the presence of normally functioning liver;
• cirrhosis with subsequent onset of death;
• inflammation of the gall bladder, the formation of stones in its ducts due to the reduction of the liver;
• the development of chronic hepatitis, which will periodically move in the acute stage;
• loss of appetite, occasional meals, which in the future will cause concomitant gastrointestinal disease (ulcer, gastritis, dyspepsia, flatulence);
• increase in body dimensions, which will have the static pressure on the abdominal tissue located in circumference.

Women who are pregnant, diffuse changes in the liver and pancreas gland, can cause compression of the fetus, its hypoxia, as well as contribute to preterm generations. Therefore it is so important to promptly begin treatment of a disease, and to keep the state of health of the digestive organ under constant control.

Registration of the article: Mila Friedan

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