Glycerin liquid. Instructions for use in neurology, cosmetology, adults, children

Instructions for use of the liquid form of glycerol - a document of a medical nature, in which the chemical is displayed composition of matter, it belongs to a specific pharmacological group, indications for use in medicine, cosmetology.

The properties of glycerol, side effects, and contraindications for use against people having comorbidities individual intolerance or polyhydric alcohol.

Composition of liquid glycerol

Instructions for use of inorganic substances - liquid glycerol states that it is one of the simplest trihydric alcohols, which is denoted by the formula C3H5 (OH) 3.

Due to its glycerol polyhydric alcohol different from the conventional compounds. He's a sweet taste and its texture is very thick. Excellent dissolves in water, acids, hydrogen-based substances.

As liquid obtained glycerol

First chemical compound of glycerin was derived and indicated by the German scientist formula - Karl Scheele (1779), as a byproduct of saponification of fats lead oxides.

Modern methods of glycerol synthesis based on thermal decomposition of propylene. This material was subjected to chlorination in a copious temperature +500 ° C. The resulting chemical reaction produces an intermediate - allyl chloride.

Thereafter, hypochlorous acid was added thereto to give chlorohydrin. The final step is the synthesis of glycerol chlorohydrin compounds of alkali saponification. This method is considered to be the least costly from a material point of view, but also allows you to get high quality polyol with minimal impurities other chemicals.

Also, glycerin may be produced from wood meal, corn or potato starch, monosaccharide. For this purpose, the procedure glycol fermentation, during which sugar undergo chemical hydrogenation.

Furthermore, a method is known by which glycerol is produced by the oxidation of propylene to give substance acrolein (has high toxicity, carcinogenic, causes oncology).

The finished acrolein and isopropyl pair passed through the catalyst containing the oxides of magnesium and zinc. Intermediate product of the chemical reaction is allyl alcohol. In the conditions of temperature of 190 to 270 degrees Celsius by reaction with hydrogen peroxide, a chemical liquid is converted into glycerol.

Description of the release form

Glycerin liquid, instructions for use which stipulates that it is syrupy substance which does not express the color and smell, completely transparent. It is considered a hygroscopic chemical.

Pharmacological form glycerol registration - it epicutaneous solution for external use. The pharmacy networks can be found in glass vials or 50 ml plastic tubes of the same volume.

pharmachologic effect

Glycerin - a chemical main pharmacological effect of which is to provide a softening effect on epithelial tissue. Also, the polyhydric alcohol is widely used as a cheap solvent for such organic compounds as Protargolum, boric acid, tannin.

In the reaction of glycerol with the skin surface shows no active chemical reaction saturating only its surface layer. At the same time the drug is able to penetrate the mucous membranes of the human body.

Pharmacodynamics and Pharmacokinetics

Glycerin liquid, instructions for use which stipulates that the pharmacodynamics of chemical is in its neutral operation with respect to the skin surface, is a good solvent.

It is able to moisten the epithelium, preventing the formation of cracks, as well as excessive dryness of the skin. It is used as the adjuvant in the composition of some gels and creams. Pharmacokinetics of glycerol is not currently understood, but the clinical trials data in this direction - no.

Indications and application

Liquid glycerin has found wide application in medical, industrial, cosmetic industries.

Glycerine in cosmetics

The modern cosmetic industry glycerin is used as a component of nutritional basics to ensure adequate skin hydration. Polyol recommended for use as part of nourishing creams for the face, hands and feet, if necessary to achieve the following cosmetic effect:

• clean the pores of the skin of blackheads;
• provide moisturizing too dry epithelium;
• smooth wrinkles;
• derive from the surface layer of the skin toxic substances, as well as the biochemical compounds formed during the metabolism.

Liquid glycerol contained in the cosmetic composition means which is applied in a room with a dry and hot air, having a lifting effect. If the task is to achieve wetting of the epithelial surface, the indoor climate should be warm, as well as the air humidity of at least 70%.

Glycerin in neurology

Glycerin liquid, instruction manual which says that it has no direct evidence for use in neurology, is used as a means of symptomatic or permanent therapy. Some neurologists prescribe to their patients the polyol as an adjuvant in combination with other drugs.

Glycerin used in neurology in the presence of the following diseases:

• brain stroke - used as a means to reduce brain swelling and reduce the rehabilitation period;
• intracranial pressure - it is considered that the substance improves blood circulation, prevents stagnation of venous blood;
• traumatic brain injury - proved that small doses of glycerol accelerate during repair damaged tissue, while minimizing the negative effects of the disease.

Unauthorized treatment of neurological diseases preparations based on glycerol - unacceptable. Medication should be administered only specialized professionals. Especially when it comes to pathologies such as stroke or traumatic brain injury.

Glycerin in general medicine

Glycerin liquid, instructions for use which stipulates that in general medicine substance is used as an auxiliary solvent, or a basis for ointments, creams, medicinal gels, shown under the following conditions:

• allergic dermatitis;
• infectious diseases of the skin surface (glycerin has bactericidal properties);
• eczema;
• alopecia;
• seborrheic dermatitis;
• Pink zoster (used to reduce itching and eliminate dryness and flaking of the skin at the point of defeat viral microorganisms);
• hives;
• the formation of cracks and other wounds caused by excessive dryness of epithelial tissues, the influence on them of toxic substances;
• fungal diseases (used in the composition of antimycotic creams);
• treatment of acne on the face.

Despite the fact that glycerin is widely used in general medicine, the active components other drugs are chemical compounds having more potent pharmacological claims.

Contraindications

The polyhydric alcohol is not particularly harmful chemical substance, but all the same as any other drug has a number of contraindications.

They consist in the following limitations to the use of glycerol as in medicine and in cosmetic purposes:

• idiosyncrasy chemical substance, expressed in the form of allergic reactions (redness of the skin in the application of glycerine, rash, pruritus);
• presence of extensive wound formations, trophic ulcers (should not be applied directly on the glycerol damaged areas of the epithelium, as this would cause severe pain and swelling);
• too oily skin;
• Use of glycerol in conditions of the room, where the predominant dry and hot air (in this case moisturizing effect is not achieved, and a polyhydric alcohol draws water from the epithelial cells, causing injury person).

Depending on the type of disease as well as conditions of the skin, a physician prescribing medication can detect other factors preclude the use of glycerin in the therapeutic purposes.

Side effects

The manufacturer does not allocate a separate list of the specific reactions of the body, which could be attributed to the category of side properties. The drug is well tolerated even by patients who have a tendency to individual allergic dermatitis.

Instructions for use of glycerol, the dosage

Procedure for the use of liquid glycerol as main or auxiliary drug depends on the age group of the patient, as well as the intended use of the polyhydric alcohol.

Glycerin for adults

There are several methods cutaneous surface treatment using glycerol. If the drug is used in pure form, rather than in creams, ointments or gels, that during application the following dosage rules must be observed.

Type of therapy	Procedure and dose
Processing epithelial surface	Dilute drug in warm water at a ratio of 1 to 3 and then uniformly distributed over the treated area of ​​skin. If dermatitis or excessive dryness of the epithelium, this therapeutic procedure is done 2 times a day for 10 days.
mucosa	Performed moisturizing and bactericidal applications. For this purpose, a 30% glycerin solution, which is lubricated damaged mucosal site. Most often used as an aid in the treatment of inflammatory processes.

Glycerin for children

According to the rules on the use of glycerol instructions, safety, and efficacy of the drug for children has not been established clinically. Despite this, some pediatricians recommend that parents use a polyol as preventive and antibacterial agent, lubricating nostrils of the child before going out in the cold season.

Glycerine Baby

Chemical is not used as a therapeutic agent for the treatment of newborns. Clinical studies have not been conducted, therefore, the drug manufacturer does not have the information.

For security purposes, not recommended for treatment of newborns with glycerol. It comes as a liquid form of the drug, and the use of the substance as part of other medicines.

Glycerin Pregnancy and hepatitis B

While carrying a baby or breast feeding his connection polyol used only in those Where the use of the drug is greater than the probability of potential harm to the developing to kid.

In most cases, glycerine not used by pregnant women. It is believed that the molecules of polyol can get into the mother's bloodstream, and thus penetrate into the tissue of the fetus.

Overdose

Throughout the history of use of glycerol as the main or auxiliary drug was not detected not a single case of overdose.

This is due to the fact that the drug is practically not absorbed into the deeper layers of the skin. In the treatment of mucosal overdose also excluded since the medicament is applied to a limited portion of tissue.

Interaction

The result of interaction with other drugs - is unknown, because clinical trials have not been conducted. The fact that glycerin is included in most moisturizing creams, ointments and gels indicates the low chemical reactivity of the substance.

Terms of sale

To purchase a bottle of glycerin, do not require a prescription, or the attainment of a certain age limit. The drug is freely available, does not belong to the category of narcotic substances and precursors. The drug can be found in retail pharmacy chains even a small village.

Storage conditions

The drug should be stored in a dark and cool place to be inaccessible to children.

Compulsory compliance with the conditions of temperature, which should be no higher than 25 degrees Celsius.

Higher rates may reduce the shelf life of the drug, as well as lead to the loss of its pharmacological properties. If the storage of the glycerol is carried out in the home, for these purposes are best suited refrigerator, inside of which will be allocated a separate regiment.

Shelf life

The recommended duration of storage of the vial with glycerol, for which he does not lose their therapeutic properties, is 5 years. The manufacturer gives a guarantee that if all the rules of storage of the drug, then over a specified period of time, its components are not exposed to chemical degradation was observed.

special instructions

There is no direct medical contraindications, but still the drug should be used with caution in people who have the following diseases:

• diabetes, where blood glucose level is able to rise to a level above 8 mM, and the patient received injections of insulin replacement therapy;
• cirrhosis induced intoxication chemicals, prolonged use of alcoholic beverages, hepatitis, neoplastic processes;
• chronic renal failure (no matter what the reason provoked organ pathological condition).

Despite the fact that glycerol is a polyhydric alcohol type, its use as a drug does not entail a reduction reaction or concentration. Therefore, a drug approved for treatment of drivers of vehicles, as well as operators of machines and equipment.

Price, where to buy glycerol in liquid form

Liquid glycerin, complete with who is the detailed instruction for use, sold in pharmacies. Up to 40-ies of the last century, this tool can be found in beauty salons and perfume stores.

At the moment - is a drug which has to cosmetics indirect relation. Also, the liquid form of glycerol is used as the basis for electronic cigarettes.

Registration of the article: Mila Friedan

Video of glycerol

How to use glycerin for beauty: