Preparations of a new generation of high blood pressure, the list of which is constantly growing, are highly effectiveness in the treatment of high blood pressure and minimal risk of side symptomatic picture. Drugs quickly cropped signs of the disease, prevent its re-emergence, providing prevention of serious complications.
diuretics
Current drugs for hypertension therapy possessing diuretic effect is needed in order to excrete the accumulated liquid together with the salts. The liquid accumulating in excessive amounts in the soft tissues, becoming one of the most frequent causes of increased pressure. The purpose of prescribing diuretic spectrum - to preserve and maintain the functioning of the heart muscle and organs of the circulatory system.
old generation Diuretics have many adverse events, and together with the liquid washed from the body calcium, which negatively affected the internal organs. The newest drugs diuretics do not have such a negative impact, while maintaining the level of calcium in the body, so that they can be taken on a regular basis. a new generation of diuretics:
- hydrochlorothiazide;
- spironolactone;
- triampur;
- Indapamide.
Diuretics included in a comprehensive treatment of hypertension along with other medicines. The only cure for a new generation of hypertension with a diuretic effect, which can be used as monotherapy in hypertension - indapamide.
Lack of potassium-sparing diuretics advanced that their effect is less pronounced, requiring a longer taking them with increased dosage.
adrenomimetiki
Medications are divided into 2 subgroups:
- selective action which is aimed at individual receptors;
- nonselective - have an impact on several receptors.
The task of a new drug for hypertension from the group agonists - arrest the symptoms of shock, which experiences the body after an abrupt increase in vascular tone. A list of resources for hypertension:
- clonidine;
- methyldopa;
- mezaton;
- Midodrine.
These drugs belong to the emergency. They are assigned only in case if the patient is difficult to tolerate hypertensive crisis with severe symptomatic picture.
Beta-blockers
it tablets against hypertensionReducing the frequency of contractions of the heart muscle. These include:
- carvedilol;
- nebivolol;
- betaxolol;
- Bisoprolol.
beta-blocker group:
- Nonselective: sotalol oxprenolol, carvedilol.
- Selective: nebivolol, betaxolol, atenolol.
These drugs are a new generation of hypertension decrease heart rate, which contributes to the normalization of pressure for hypertensive crisis. The drugs in this group is to stop the process of synthesis of prorenin in the kidneys, thereby blocking occurs renin-angiotensin.
Beta-blockers promote relaxation of blood vessel walls, whereby the volume of blood flowing through it decreases. This leads to rapid blood pressure decrease.
Beta-blockers are a new generation of appointed mostly burdened with current hypertension accompanied by tachycardia, cardiac ischemia, cardiac arrhythmia. Prescribed means in the case where the cause of hypertension steel deviations in the functioning of the endocrine system.
new generation of drugs for high blood pressure in the group administered to patients with resistant form of hypertensive disease. The course of treatment of hypertension these drugs takes 2 to 4 weeks. They are used in complex treatment and as monotherapy.
ACE inhibitors
ACE inhibitors are a new generation of impact on the mechanisms that influence the developing hypertension. Medication to inhibit (stop) the process, whereby there is a reduction of pressure while maintaining its performance at one level, prevents the appearance of hypertensive crisis.
Treatment of the disease is always carried out with the help of these hypertensive drugs. These are the main means of treatment, regardless of the severity of the case. Modern medicine from hypertension from the group consisting of ACE inhibitors:
- ramipril;
- captopril;
- lisinopril;
- enalapril;
- quinapril;
- trandolapril;
- Perindopril.
Form of the drug release can be an injection and a tablet. Most drugs are available in tablet form, which simplifies self-administration by the patient.
The spectrum of effects on ACE inhibitors in hypertension body - they lower the tone of blood vessel walls, whereby the amount of blood be injected is enhanced. Long-term administration of ACE inhibitors siphons salts, which helps to regulate the pressure and keeping it at the same level.
Unlike the older generation of funds, the new ACE inhibitors do not adversely affect the concentration of potassium, preventing the development of many adverse events. This is the most common and effective drugs given to patients with a diagnosis of hypertension.
Sartana
Medications with the latest generation of high blood pressure:
- losartan;
- olmesartan;
- candesartan;
- valsartan;
- irbesartan;
- Eprosartan.
These agents have a cumulative effect. The full range of positive effects on the organism hypertension disclosed in 10-14 days after the start of the course. New tools Sartana milder effect on the body, do not cause adverse symptoms such as dry cough attacks, as do the older drugs.
The principle of operation is sartans inhibitory effect on angiotensin receptors. After a course of sartans blood pressure will be maintained at one level, it is prevented decrease or increase. the new generation do not cause habituation of the body with prolonged use, and therefore do not need to increase dosage.
Sartana positively affect the central nervous system, increasing the degree of the body's resistance to stressful situations, respectively, decreases the risk of hypertensive crisis. Sartai lowering blood pressure may be given to patients who have hypertension accompanied by arrhythmia and other diseases of the heart muscle.
Calcium channel blockers
Assigned only as an adjunct to medical treatment. Drug treatment of hypertension in this group provides long-lasting results, stabilizes blood pressure and prevents its re-jumps under the influence of provoking factors.
Formulations normalize and control cardiac muscle, preventing re-narrowing of the vascular wall, leading to problems with pressure. Calcium channel blockers have a positive influence on many internal processes. New drugs can quickly reduce the pressure by increasing the bed of blood vessels. Recommended tools in this group:
- lacidipine;
- amlodipine;
- verapamil;
- diltiazem;
- Nifedipine.
Basic substances drugs enter into interaction with cell membranes, blocking the entry of calcium into them. Vasodilation occurs due to blocking contractile protein production processes.
In addition to lowering blood pressure, antiarrhythmic agents have an effect that is the cuts pulse rate. Reducing the load on heart muscle is achieved by reducing the degree of resistance arteries with respect to the bloodstream.
This group of drugs in pharmacology is relatively new. The spectrum of their actions and the mechanisms leading to blood pressure reduction, based on a cellular level. The advantage of use in hypertension is possible to reduce the pressure that a short period of time, but the process is calm, smooth character without creating internal systems of the body and stress shock.
Calcium channel blockers are essential if hypertonic disease occurred on the background of type 2 diabetes or illness was the result of atherosclerosis and flows with complicated symptomatic picture.
direct vazadilatatory
Vasodilators of the latest generation have hypertension expanding action on nerve fibers having vasomotor action, thereby expanding the lumen in the bloodstream.
Vasodilators reduce the burden imposed on the heart muscle. Antihypertensive effect is achieved by regulating the heart. Drugs have a positive effect on the heart and blood vessels in heart failure. New drugs group - minoxidil and hydralazine.
Vasodilators contribute to enhanced soft tissue regeneration processes at the cellular level and saturate the internal organs of oxygen. Hypertension impact means on the body of this group is based on the principle of proper redistribution in blood vessels. When the active components of the drug into the body, there is a forced dilation of the blood vessel walls, thereby rapidly decreases blood pressure.
In view of the direct vasodilators are the means 3 rows high risk of unwanted side symptoms. They are used when other medicines do not give a positive therapeutic effect or have only short-term effect.
