Elevated levels of human chorionic gonadotropin often indicates a pregnancy at a very early period - up to 6 days from the moment of conception. But in some cases, its increase is not always indicative of conception, perhaps, in the body develop any pathological processes. HCG standards in non-pregnant and pregnant women differ.
In some cases it is necessary to hand over the analysis
The main indication for the delivery of the analysis on the gonadotropin in the blood - the absence of menstruation, which can indicate both the conception and on gynecological diseases. The amount of the hormone in the latter case is also increased. HCG in nonpregnant increases with:
- Cancer tumors develop in the ovaries, uterus, lungs or digestive organs;
- horionkartsinoma occurs:
- Suspected ectopic location of membranes eggs.
Assay for determination of the hormone is performed in the following cases:
- Diagnosis of early pregnancy;
- assessment of the state of health after abortion;
- determining the risk of miscarriage;
- diagnosis of the presence of fetal heart defects;
- suspicion of amenorrhea;
- exclusion of ectopic pregnancy;
- hormonal failures after miscarriage or abortion;
- observe the dynamics of treatment of trophoblastic disease.
In nonpregnant test may show hormone excess normal range due to long-term use of hormonal contraceptives.
Rules of study
To study does not give a false positive result, lease analysis is recommended for 4-5 days of menstruation. To analyze blood taken from a vein. Fence biological material is carried out only on an empty stomach. You can not eat anything to eat for 6-8 hours before analysis. Allowed to drink water, but in limited quantities.
The result to be as accurate as possible, it is necessary to prepare properly: on the eve of refuse from alcohol, smoking and reduce the intensity of exercise. Take the necessary analysis in a quiet physical and psycho-emotional state.
Violation of any of these rules can lead to false-positive results and distort the diagnostic picture.
What is the normal rate for non-pregnant
HCG is normal non-pregnant should not exceed the established limits, its increase or decrease indicates the development of abnormalities in the urogenital system. The table shows some of hCG should be women, not to bear a child:
Indicator | limit of normal |
Color | from 0.85 to 1.05 |
leukocytes | from 4 to 8.8 109 / L |
reticulocytes | from 2% to 12% |
band neutrophils | 1 to 6 |
segmented neutrophils | 47 to 72 |
basophils | 0 to 1 |
monocytes | 3 to 11 |
lymphocytes | 19 to 37 |
platelets | from 180 to 320 109 / L |
ESR | from 2 to 15 mm / hr |
Norma hCG in the blood of pregnant women should be from 0 to 5.
The causes of variances in non-pregnant
The rejection rates in most if the smaller side of the hCG standards without the pregnancies affected by different factors.
If there is no conception, and the hormone concentration is increased, it is recommended to be tested again.
If the second time level shows requiring an integrated women survey to identify the causes.
elevated levels
Normal levels of hCG in the absence of pregnancy should be at zero. If the result shows a value above 0 hormone, causes may be:
- the presence of the female body biological substances that are not responding properly test;
- development of kidney cancer tumors, liver, breast, colon, stomach;
- production of hCG by the pituitary gland;
- recently conducted an abortion;
- hormonal disbalance;
- infectious diseases of the urinary system.
Pregnant body actively produces human chorionic gonadotropin. He slowly eliminated from the body, its concentration remains high after the recent birth abortions.
If a woman takes hormone drugs from the group, there is a probability of a false positive result. Outside gonadotropin pregnancy rates can be significantly increased during menopause due to hormonal changes the body's total.
Result from 5 to 25 IU is considered a gray zone that is not a confirmation of pregnancy. In this case, you want to repeat the study in 2 days. The most dangerous cause of increased hormone content in the absence of fertilization - the development of a tumor that produces gonadotropin.
In most cases, these tumors are malignant origin.
If non-pregnant women hCG is growing, it requires an expanded inspection, identifying tumor and determination of its exact location.
reduced level
If the level of hCG is less than 0, it is considered a low result. This value indicates the absence of pregnancy. If the hormone reduced the concentration observed in pregnant women, it is an alarming sign, which is a high probability points out that the development of the embryo occurs with anomalies, there is a high threat of spontaneous rejection embryo.
If hCG depending on the gestational age less than 50% and more, there is reason to suspect an ectopic or the stood pregnancy, placental insufficiency, perenashivanie, placental abruption or fetal death late in terms.