Many patients who receive analysis on estradiol (E2), wondering what it features. Under this name is commonly understood as a hormone (a type of estrogen), which is based on a steroidal nucleus. Analysis of estradiol in women indicates the presence or absence of abnormalities in the reproductive system.
Why rent analysis
This hormone is produced mainly by the ovaries, but there are several other bodies are also responsible for its production. This placenta tissue, adrenal glands, male testes (testicles).
The content of the hormone in the blood depends on the work of many organs:
- Under its influence is formed follicle in the ovary during each menstrual cycle.
- Proven impact on female libido.
- Under the influence of this and other hormones is regulated by the nervous system.
- It is going the correct preparation of the uterus to the fetus nurturing, and during pregnancy, provided adequate circulation.
- On the amount of the element depends on the state of the bone tissue.
The lack or excess of hormone leads to pathological changes in the organism. There are a number of indications in which to donate blood estradiol, among them:
- infertility;
- breast;
- menstrual disorders (including before the onset of menopause);
- early menopause;
- early (or conversely later) puberty;
- uterine bleeding;
- risk of miscarriage;
- osteoporosis.
Checking is also shown prior to IVF.
Preparation and carrying out procedures
Technique of taking simple analysis. The doctor, appointing laboratory study should inform the patient about the need for proper preparation. On compliance with the following recommendations will depend on the result of the analysis:
- 2 days prior to donate blood, it is recommended to reduce physical exertion.
- Within 1-2 days prior to assay doctors are advised to minimize the amount of fatty foods in the diet. It should also refrain from any alcohol.
- Before the study within 2 days should not be sexual intercourse.
- If a woman diagnosed with any viral or infectious diseases, the biomaterial delivery should be postponed.
- You can not donate blood after the X-ray.
- In the morning before should not be going to the clinic to eat and drink, in other words, the analysis is done on an empty stomach.
The procedure for giving blood from a vein is completely standard. A nurse treats alcohol work area on the elbow, and then makes the puncture needle from the syringe and take the right amount of blood. Immediately after that, the place of puncture impose a cotton swab dipped in alcohol.
Norm and deviation
The level of hormones in the body of women depends on several factors: age, day of the menstrual cycle. It is extremely important to consider the presence or absence of pregnancy.
In reproductive age in women there is a high percentage of content in the amount of hormones during menopause is reduced.
For this reason doctors always indicate the age of the patient.
As for the cycle, the opinions of doctors disagree. Some people recommend to do the analysis only for 4-6 day from the beginning of the cycle, while others believe that the best time - 20-21 days.
Among women
As noted above, the amount of hormones in the female body depends on the age of the patient:
| How old woman | Allowable contents hormone (pg / ml) |
| Children aged 0 to 2 years | In this period of life in the blood of girls this hormone is completely absent. His record - 0 |
| The girls, aged 2 to 3 years | At this stage, a small amount is detected. The maximum content is 22 |
| Children over 4-6 years | At this age, the standard figure reaches 22. Slight deviation |
| Adolescent girls from 7 to 14 years | Puberty coincides with an increase in hormone levels. The amount of estradiol is 30 |
| Girls 14-16 years | For minimum accepted figure of 30, the maximum may be 60 |
| Girls and women in reproductive age (16 to 50 years) | A large range from 58 to 480 |
| Women in menopause (over 55 years) | The maximum rate can reach 85. Some patients over the years, the level can drop to 0 |
In pregnant women as the norm consider other indicators:
- in the first 1-3 months the level rises to 210-6300;
- for 4-6 months prior to further growth 8000-19000;
- starting from 7 months to the time of delivery content growth hormone is from 11800 to 37000.
Excess hormones causes:
- disruptions of the menstrual cycle;
- excess weight;
- appearance of acne, skin desquamation;
- sleep disorders;
- weakness.
With a lack of E2 may appear:
- violation of the cycle;
- depression;
- loss of hair on the head;
- increased growth of hair on the body (arms, upper lip, chin);
- reduction of breasts.
men
In men, blood test results to estradiol following:
- boys from 0 to 11 years - the maximum rate of up to 20;
- in men of reproductive age - from 7.6 to 42.6.
Increased content is observed at:
- obesity;
- long-term smoking;
- cirrhosis;
- diabetes;
- oncology;
- failures in the endocrine system.
Hormone deficiency is often accompanied by inflammatory processes, rapid weight loss, abandonment of animal food.
