Rosuvastatin tablets for cholesterol. Indications for use, price

Rosuvastatin - a drug with lipid-lowering properties, which is used to lower the level of bad cholesterol in the blood. Tablets are usually used in long courses, they relieve not only of the main, but also of the concomitant manifestations that arise against the background of atherosclerotic changes in the vessels. The medication is considered effective, but the appointment is made by the doctor after receiving the examination results.

Composition and form of release

The medication is available in the form of tablets for oral use. They are small in size, covered with a film shell, placed in blisters of 7 or 14 pieces. Plates are placed in cardboard boxes, which can contain 1-4 pieces.

A description is attached to the plates indicating the features of the treatment and possible contraindications and complications. The composition of the tablets includes the main component rosuvastatin, which has a therapeutic effect.

The tablet contains auxiliary ingredients:

• Magnesium stearate.
• Corn starch.
• Povidone.
• Microcrystalline cellulose.
• Hypromellose.
• Titanium dioxide.
• Macrogol.

The amount of the main component per 1 tablet can be 10, 20 or 40 mg.

Terms of sale, prices

Rosuvastatin is a cholesterol pill sold in pharmacies after presenting a prescription form certified by a doctor.

The cost of tablets ranges from 300-1000 rubles. per packing. The price depends on the region of distribution and the specific pharmacy, as well as the number of tablets in the package.

Pharmacological properties

The drug belongs to the group of lipid-lowering drugs with pronounced properties. It helps to lower bad cholesterol levels, which can lead to plaque formation and poor circulation.

It also prevents high levels of bad cholesterol from rising when eating large amounts of fat-rich foods. If patients have plaques in the vessels, an increase in their size is prevented, followed by closure of the lumen and impaired blood circulation.

The complex effect of the drug on the body reduces the likelihood of complications against the background of the progression of the pathological condition.

Pharmacodynamics and pharmacokinetics

The drug acts slowly, that is, after a single intake of the daily rate, the therapeutic effect does not immediately occur, but it can be noted 1-2 weeks after the start of the course.

The mechanism of action of the drug is based on the ability of the active substance to control the level of cholesterol in the blood of patients suffering from atherosclerosis of various forms and severity.

The tool has a complex effect on the body:

• Helps improve the distribution of fat in the body. When they enter the body, assimilation occurs faster, which ensures normal metabolism.
• Reduces the likelihood of the formation of cholesterol plaques with their subsequent attachment to the walls of blood vessels. An increased level of bad cholesterol inevitably leads to such disorders, which provokes a deterioration in blood circulation and other disorders.
• Improving metabolic processes has a positive effect on the functioning of the heart and vascular system. There is an improvement in the condition of the walls of blood vessels. If they are damaged, cholesterol plaques attach more quickly to this area, provoking further tissue damage.
• The drug prevents further progression of atherosclerosis if its symptoms are already bothering the patient.

When taken orally, the active substance is absorbed into the systemic circulation through the walls of the small intestine and is distributed throughout the body. Eating food slows down the absorption and processing of the ingredient somewhat. The maximum concentration of the component in the blood is reached 2 hours after the use of a single dose.

The processing of rosuvastatin occurs in the liver, after which its metabolites are excreted by the kidneys. Changes in pharmacokinetic characteristics depend on the organism of a particular patient. Sometimes the withdrawal period is prolonged, as well as the time of the onset of the therapeutic effect. The drug can accumulate in a minimal amount in the body, especially with prolonged use.

Long-term courses ensure the preservation of the therapeutic effect even after stopping the intake of the tablet preparation.

Indications for use

Rosuvastatin is used for patients with vascular abnormalities.

Cholesterol tablets have the following indications for prescription:

• Increased blood cholesterol levels. The medicine is prescribed as part of complex therapy, as well as in addition to dietary nutrition.
• The appearance on the walls of blood vessels of cholesterol plaques of different sizes. Usually, treatment is recommended to start before their formation. If the patient has not previously consulted a specialist, it is possible to use it at different stages of atherosclerosis.
• Violation of blood circulation against the background of the overlap of the lumen of the vessels of the cholesterol plaque. The drug is used as an auxiliary method in combination with drugs from other groups.

The drug is used even if patients have other complications from the cardiovascular system.

Contraindications

Do not use tablets if there is an intolerance to the components of the composition or a history of such reactions.

Other obstacles include the following conditions:

• Myopathy at different stages of development.
• Liver pathologists of viral origin. Viral hepatitis of various types can occur in an acute form if pills are used.
• Liver cirrhosis, fatty hepatosis.
• Liver failure, in which the liver function is significantly impaired, complications from other organs appear.
• Renal failure
• Infectious kidney disease in the acute stage. After the relief of severe symptoms, it is allowed to use the medicine according to the indications.
• Gastrointestinal bleeding resulting from perforation of the intestinal wall or stomach.
• A state of shock, in which there is a critical decrease in blood pressure indicators.
• Infection of the blood in the acute stage.
• Acute mental disorders.
• Severe endocrine disorders.
• The recovery period after surgery on the organs of the digestive tract.
• Acute cholecystitis, calculous form of pathology.
• Exacerbation of severe chronic pancreatitis. The drug can be used after elimination of acute manifestations.
• The patient's age is up to 18 years.

With extreme caution, the agent is used for patients over the age of 65. The period of pregnancy and breastfeeding is considered an absolute contraindication for therapy. Usually, treatment is postponed during these periods. If, during lactation, the use of tablets is necessary, feeding should be discontinued for the entire period of administration.

Method of administration and dosage

Rosuvastatin is a cholesterol pill that is taken only orally as prescribed by a specialist. A preliminary diagnostic examination, laboratory blood diagnostics, determination of the level of harmful cholesterol are carried out.

The dosage of the drug and the duration of its use is determined for patients, depending on the symptomatology of the pathology.

Pathology stage	The dose and duration of the drug
Initial	At the initial stage, patients take 10 mg of the drug per day. For 1-2 weeks, the doctor monitors the patient's condition, assesses the blood counts using laboratory diagnostics. After that, a decision is made to cancel or prolong treatment, adjust the dosage.
Progressive	With severe symptoms, the dosage of the drug per day is increased to 20 mg. Patients use it for 14 days in a row. Monitoring blood counts allows you to evaluate the effectiveness and adjust the dose and duration of the course.
Launched	At an advanced stage, when symptoms are accompanied by complications from other organs. The dosage of the drug is 40 mg per day, and the duration of therapy can be up to 4 weeks.

It is recommended to take the tablets at the same time of the day, regardless of the meal. A prerequisite for treatment is considered to be the use of a sufficient amount of liquid to accelerate the dissolution of the film shell of the tablet.

Treatment can last up to 8 weeks if the doctor considers it appropriate. Longer courses are also prescribed only by a doctor, especially in the case when the patient takes higher doses of the medicine and combines it with other groups of medicines.

Side effects

Rosuvastatin - cholesterol tablets, which often provoke complications from the internal organs, even if all the recommendations of a specialist are followed.

Disorders affect the work of different systems, which negatively affects the general condition:

• On the part of the gastrointestinal tract, complications are manifested in the form of diarrhea or constipation, nausea and impaired digestion. The condition is aggravated by the addition of abdominal pain, bloating. Patients often report lack of appetite and intense thirst.
• Often, patients speak of severe weakness and rapid fatigue, headache, and dizziness. Insomnia can bother patients, even in the absence of such complications in the anamnesis, which only aggravates the symptoms. In patients with chronic neurological disorders, an aggravation of manifestations is observed.
• Muscle and joint pains are not so common, but can occur when diagnosing pathologies of the musculoskeletal system of a chronic form.
• On the part of the cardiovascular system, complications often manifest themselves in the form of tachycardia, arrhythmias and pain in the region of the heart. Fluctuations in blood pressure indicators are less common, but experts cannot exclude them.
• An allergy to a medication usually manifests itself in an acute form, accompanied by the spread of a rash over large areas, severe itching and burning of tissues, and the appearance of inflammatory foci. The condition is aggravated by the addition of symptoms of allergic rhinitis or conjunctivitis.
• Sometimes manifestations affect the respiratory system, accompanied by cough, shortness of breath, aggravated by emotional and physical exertion. If the patient suffers from bronchial asthma, the symptoms are more acute and persist for a long period of time.

Side effects can manifest themselves in an acute form, but often the manifestations disappear after refusal of therapy. If they are aggravated, it is necessary to prescribe drugs to normalize the condition.

Overdose

Cases of drug overdose have not been recorded by specialists, but their development cannot be ruled out, since the body of each patient individually reacts to the components of the composition. With the abuse of the medicine or a single dose of a large number of tablets, the aggravation of adverse reactions is possible.

Overdose can be accompanied by bouts of vomiting, diarrhea and abdominal pain. The condition is aggravated in the absence of therapy. Symptoms can include severe headache, dizziness, and weakness. Fluctuations in blood pressure indicators are observed in patients with hypotension or hypertension.

Allergy in case of an overdose manifests itself in an acute form, accompanied by the spread of a rash over large areas of the skin, severe itching and skin irritation. Combing the skin leads to damage, which increases the likelihood of complications in the form of infection.

If symptoms of an overdose appear, you must stop taking the pills and visit a doctor. A specialist may prescribe a gastric lavage, after which he selects symptomatic treatment depending on the manifestations. The drug has no specific antidote, so the treatment regimen for different patients is different.

special instructions

Rosuvastatin - cholesterol tablets, which are allowed to be taken in long courses, if necessary. But patients on their own do not prolong the course and do not increase the dosage of the drug.

With prolonged use of the medication, monitoring of blood counts is necessary. In the laboratory, experts identify the level of bad cholesterol. Sometimes it is necessary to adjust the dosage and duration of the course, but the decision is made only by the doctor.

When using pills, it is recommended to simultaneously follow a diet that involves reducing the amount of foods with an increased level of harmful cholesterol in the daily diet. If the patient suffers from obesity, diet is considered an essential component of therapy, since without adherence to dietary rules, the therapeutic effect is significantly weakened.

Drug interactions

The medication is not prescribed in combination with other lipid-lowering drugs, as the risk of complications as a result of an overdose or other complications increases. If it is necessary to prescribe antacids, it is necessary to take a break between taking them for at least 2 hours.

Violation of this rule reduces the effectiveness of Rosuvastatin. Erythromycin is not prescribed simultaneously with tablets, since the effectiveness of lipid-lowering drugs is significantly reduced. The decision to combine several medications is made only by the doctor after examining the patient.

Analogs

The tool has substitutes that, if necessary, can be used by patients if the original is not prescribed for various reasons.

The most effective substitutes:

• Acorta - a tablet formulation based on rosuvastatin, which can be used for arteriosclerosis, an increase in the level of harmful cholesterol against the background of obesity and metabolic disorders. The tablets are used in an individual dosage depending on the manifestations and the presence of concomitant complications in the patient. Like the original, they are assigned after a preliminary examination.
• Pravastatin contains the active ingredient of the same name in the composition, but has hypolipidemic properties and helps to improve the condition of patients when diagnosing atherosclerosis at different stages. The tablets help control cholesterol levels, have a positive effect on metabolic processes, and stimulate the breakdown of fats. Taking medicine for long courses improves the condition of blood vessels, prevents the attachment of cholesterol plaques to their walls.
• Zokor - tablets based on simvastatin, which are often used to treat patients with different stages of atherosclerosis. Despite the presence of another active component in the composition, the drug has lipid-lowering properties, helping to prevent the progression of the disease. The remedy, like the original, can lead to the development of complications, but patients note that they occur more often with long courses.

Analogues of the drug are considered effective, but their appointment should only be made by a doctor after receiving the results of a diagnostic examination, indicators of laboratory blood tests.

Storage conditions and periods

The medication is allowed to be stored in a dark and cool place, away from children and direct sunlight.

The maximum storage period does not exceed 2 years. After the expiration of this period, the application is prohibited.

Rosuvastatin - effective tablets based on the active ingredient of the same name, which are used to get rid of the symptoms of atherosclerosis and control blood cholesterol levels. The medicine is often prescribed in long courses, since the effect is not observed for several days, but after prolonged use it persists for several weeks.

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