Description medications
Metformin belongs to the pharmacotherapeutic category "Gipokglikemicheskie means" oral use of the biguanide group.
There are various trade names of medicines:
- metformin;
- Metformin: Zentiva, Long, CF, MS, Richter, Teva.
The main active component - metformin.
release forms - tablets and sustained-release tablets or sustained release.
properties
The therapeutic effect of the drug depends on the action of the active substance - metformin.
The basic qualities:
- gluconeogenesis inhibition process;
- fat oxidation;
- The generation of free fatty acids.
Metformin increases susceptibility to insulin receptors and improves glucose processing. The medication does not affect the change of the number of insulin in the blood and reduces the ratio of insulin in the free and bound forms, which modifies its pharmacodynamics.
According to the official statement, metformin stabilize or gradually reduces the weight of the patient.
Contraindications
On the question of whether the pregnancy metformin, the answer can be seen in the list of contraindications to each of the types of drugs allowed.
According to official instructions to the drugs during pregnancy, the drug is contraindicated with the following trade names:
- Metformin Zentiva;
- Richter;
- Teva.
metformin Zentiva
Or planning a pregnancy involves the abolition of the use of the drug and the appointment of insulin.
To reduce the risk of perinatal mortality and congenital malformations in the fetus when pregnant women are advised to maintain the level of blood glucose level close to normal.
metformin Richter
In accordance with the instructions to the drug during pregnancy to take Metformin is contraindicated Richter.
Type 2 diabetes and pre-diabetes condition in pregnant women are the basis for cancellation of Metformin. Pregnant patients with type 2 diabetes disease doctor prescribes the use of insulin.
Teva metformin
The medicine is contraindicated drinking by a pregnant woman. If you plan to or have already become pregnant, the patient takes the drug, is obliged to notify the attending physician.
Instead Metformin drug during pregnancy, insulin therapy is appointed and installed surveillance, both for the mother and child.
other species
Regarding the use of metformin during pregnancy drugs Metformin Long, Long Metformin Canon, CF Metformin, Metformin-Teva CF, MS Metformin, the instructions for medicines, there is evidence that strict Studies concerning the safety of use of these funds has not been pregnant patient.
Therefore, these brands drink Metformin pregnant permitted only when absolutely necessary, the alleged effect of the therapy for the mother exceeds the risk to the fetus.
analogs
Among the full analogue of Metformin, according to the instructions to the drug, absolute contraindications to the use during pregnancy apply to products:
- Bagomet;
- Glucophage;
- Metfogamma;
- Siofor;
- Formetin.
Other Metformin analogues can be used to pregnant patients only when absolutely needs, prescribed by a doctor.
Application breastfeeding
In accordance with official instructions to the drugs, there is information about how to use Metformin nursing mothers.
Medications Metformin Zentiva, Richter passes into breast milk. Despite the fact that the side effects of the child as a result of the use of drugs during the breastfeeding period is not fixed, nursing mothers should not take this money.
There are no data on the allocation of Metformin Teva passes into breast milk. Therefore, if there is a need for the use of medication during lactation, for the period of breastfeeding should be separate.
Metformin other brands in small amounts into breast milk, therefore the use of drugs during breastfeeding is not recommended.
sources:
Vidal: https://www.vidal.ru/drugs/metformin-5
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ac45cb5c-4394-42ca-8479-a60a7a67e0b0 & t =
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