The composition and the form of medicines
Both drugs produce expectorant effect, however, they contain different active ingredients. Bromhexine included in the main component of the same name. At the core lies Lasolvan ambroxol.
Preparations are available in different forms, so they are used for therapy, both small and adult patients. Bromhexine can be purchased in the form of tablets, syrup, drops and oral drops (for smaller patients). Mucosolvan can also be bought in the form of a syrup, oral solution, tablets, and lozenges for sucking. This medication can be purchased in capsule form providing a sustained action, which distinguishes it from other mucolytics.
Importantly, Bromhexinum produced by domestic and foreign firms, and Lasolvan released only in Germany. The maximum amount of active substance in the first drug is 30 mg. The highest content of ambroxol Lazolvanom - 75 mg.
Indications and contraindications
The difference between the drugs is small, but it is. With regard to the indication for use Lasolvan and bromhexine, the instruction is in both cases suggests these:
- chronic, acute obstructive bronchitis and which is accompanied by excretion of large amounts of sputum;
- tracheobronchitis or other combination of infectious processes different parts of the respiratory system;
- cystic fibrosis;
- tuberculosis.
Bromhexine often used for preparation for surgery on the lungs or postoperatively to prevent pneumonia. Presented by the drug is well relieve bronchial secretions from, increases the effectiveness of the intervention, diagnostic measures.
Bromhexine and Lasolvan have the same contraindications for use. They can not be used in case of individual intolerance of the main active ingredient, or additional components, a stomach ulcer in the acute stage. They must be used with caution in severe liver and kidney pathologies.
If Bromhexine banned for treating pregnant women and nursing mothers, the Lasolvan can not be taken only in the first trimester. it is not dangerous for infants. The main thing - to observe the correct dosage. Also, do not apply Bromhexine and Lasolvan together with cough medicines. Otherwise, the patient's condition will worsen, because the secret will not be displayed.
For children Bromhexine used only after reaching 6 years. Lasolvan be used to treat infants.
Side effects and overdose
Like any other analog, Bromhexine capable of giving side effects. The list of adverse reactions can include allergies, digestive disorders, exacerbation of chronic pathologies. These symptoms disappear after drug withdrawal. Overall health of the patient worsen if Bromhexine consumed in large doses.
Mucosolvan can cause the same reaction, but the percentage is much less. Some patients can be pain in the abdomen and digestive disorders, an attack of tachycardia, dizziness. Cases of overdose have not been described in the medical literature. If the patient's state of health after receiving Mucosolvan deteriorated, it is necessary to clean the stomach and seek medical advice to replace drug (if necessary).
Features of action of drugs
Differences Lasolvan of bromhexine are present and in particular the drug. Generally, cough mukotsitarny provides clearance. The bronchi are lined with ciliated epithelium that produces mucus. It absorbs harmful substances as well as pathological microorganisms inhaled together with the air. Cilia contribute to the removal of the mucus. So there is the cleansing of the respiratory system.
If the body is present infection, the process is complicated. Mucus accumulates in the respiratory tract. Independently epithelium can not cope with the situation, so the required preparations, and helps to eliminate phlegm, which is produced at an increased rate.
When wet cough better suited Lasolvan, Because it acts faster. His "work" begins immediately after entering the body. Inside gets a ready-made active ingredient. As for bromhexine, after its receipt by the body it should still be metabolized in the liver. In addition, there must be special enzymes, without which the effectiveness of the drug is greatly reduced. That is the effect of its application is seen in a few days. Lasolvan has been working for a couple of hours.
In addition, there are some differences between the drugs:
Bromhexinum |
Lasolvan |
|
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Mucosolvan additional advantage is that it is able to increase the efficacy of antibiotics in the lesion 2 times.
The differences in the efficacy and safety of medicines
Any drug should be chosen, and drink only after the doctors' recommendations. This is especially important if the child performed the treatment. Combining Lasolvan with bromhexine can, if it is needed. However, this issue is resolved specialist, as it is necessary to adjust the dosage of both drugs.
The general conclusion can be made as follows:
- On the effectiveness of Lasolvan it has higher rates, since it is a new generation of drug action begins immediately after contact with the respiratory system. Bromhexine is slower, as it still needs to be metabolized. The nature of its action less pronounced;
- Safety Lasolvan again ranked first. It gives fewer side effects than Bromhexine. Therapeutic efficacy Lasolvan higher than the risk of adverse reactions. This fact is proved by the European Medicines Agency Committee. Lasolvan - a reference preparation in developing new mucolytics;
- At a cost of Bromhexine considered cheaper. It can be bought for 20-100 rubles. Lasolvan worth 6 times more expensive.
To achieve the effect of missing a total of 36 mg of bromhexine. Lasolvan need a little more.
Features of the application and dosage
Child cough better taking Bromhexine if not observed too difficult expectoration. The dosage used depends on its structure and pharmacological properties. Bromhexine can be used before and after meals, the chewable tablets do not need to. They washed down with a slight amount of clean water. Adult patients and adolescents over 14 years of age need to drink 1-2 tablets three times a day. If there are problems with the kidneys, the liver, the intervals between doses of the drug are increased. The course of treatment is up to a month.
Bromhexinum syrup allowed to drink for children from 6 years. The dosage is 5-10 ml formulation 4 times a day. During pregnancy, women are prescribed the drug represented only if the mother's life threat is higher than the risk to the fetus.
As for Lasolvan, then there are standard rules:
- Children from 1 to 2 years old - need to drink to 2 ml of the drug three times a day;
- Infants 2 years - it is necessary to use 2.5 ml, 2 times a day;
- Adult patients being prescribed 10 ml syrup which was taken in three steps;
- Tablets are assigned adult patients and adolescents from 12 years of age. Must take three times a day 1 tablet (30 mg). The course of treatment lasts for about a week.
Inhalations with bromhexine and Lazolvanom made only by means of a nebuliser. Both drugs are bred in equal proportions with saline. Dosage and Lasolvan Bromhexinum determined strictly individually. The first drug for the procedure used more frequently.
Bromhexine and Lasolvan can simultaneously receive, however, the dosage should be adjusted. In the morning and evening time, a drug can be drunk, and in the afternoon - the other. It all depends on the severity of the patient's condition, drug release forms.
Both drugs belong to one group. Which one is better - should be decided by the patient. However, do not just pay attention to the cost of funds. In this expensive drug is not always necessary.
sources:
Vidal: https://www.vidal.ru/drugs/lasolvan__433
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 059eef4d-4dac-49a0-b5c3-a5c9a15182a8 & t =
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