Indications injections Diclofenac

General description and composition

Diclofenac is a nonsteroidal anti-inflammatory drug of wide spectrum of action. The injectable form allows the active substance is rapidly absorbed into the systemic circulation, reach the hearth inflammation and pain instantly kupiruya all unpleasant signs and symptoms. The speed feedback is important to patients in exacerbation of various chronic diseases, however, clinicians prefer Diclofenac injections. 1 vial contains 3 ml of concentrate.

The preparation includes sodium diclofenac (main component), mannitol, sodium hydroxide, distilled water, sodium pyrosulfate, benzyl alcohol, propylene glycol. Auxiliary components enhance the effect of the active substance.

pharmachologic effect

Active composition of Diclofenac solution intended for intramuscular or intraarticular injection. Pharmacological action is rapid suppression of prostaglandin enzyme - COX-1 or COX-2, which leads to the relief of pain, inflammation and swelling in the area of ​​pathological hearth.

Removal of inflammation due to lower levels of prostaglandins and other enzymatic components responsible for the disease. Diclofenac injections provide the following biochemical effects:

• pain reduction, which is based on the compression or irritation of the nerve root inflammation
• skin redness reduction in pathogenic hearth (removal of excess blood supply vessels)
• decrease swelling
• decreased platelet adhesion activity and blood thinners

Injections of much lower levels of prostaglandins in the esophagus, stomach, mainly in Structures and mucous tissues. But there is a flip side effects on the gastrointestinal tract organs - reduced resistance to pathogens, external or internal attack by several factors.

After intramuscular injection drug Diclofenac instantly absorbed into the general circulation. The peak concentration is reached in 10-15 minutes. The drug is distributed deep into the subcutaneous structures, so the maximum concentration is slightly higher in the articular apparatus. This is due to widespread use of the drug solution with rheumatic diseases.

The drug is metabolized mainly in hepatocytes (liver cells). There also is their decay. breakdown products are excreted in the urine by the kidneys or in feces. Excretion half of the dose comes after only 2-3 hours.

Indications for use

From what help Diclofenac injections? The drug Diclofenac injections are used in various fields of medicine. The main indications for the use of injections of the drug considered the following:

• Inflammation. Foci of inflammation can be localized in the pelvic organs, musculoskeletal system, with the defeat of the articular joints. Treatment of low back pain require injections of diclofenac, bursitis, Scoliotic curvature of the spine, intervertebral hernia, arthritis and arthritis, spondylitis, gouty arthritis. Additionally apply injections of other pharmaceutical groups. Acceptable treatment of other diseases for which is accompanied by inflammation.
• Pain syndrome. Diclofenac administered to treat recurrent pain in women, cancer, joint radiculopathy, dental pain, or headaches - all this range of applications Diclofenac solution. Already single dose can facilitate the patient's condition after 10 minutes.
• infection. During acute infectious diseases, particularly bacterial origin with a characteristic inflammatory lesions (catarrhal otitis, lobular pneumonia, pharyngitis, Sinusitis, tonsillitis).
• traumatic injuries. For bruises, subluxations, sprains medication will ease the pain and help the patient with first aid on the background of fractures. It helps prevent inflammation in the bone, ligament, tendon structures of the joints.
• ophthalmic diseases. eye treatment during infectious nature of the disease or in the recovery period after surgery helps prevent the development of inflammatory complications, pain.

For injections indications for use may be a variety of systemic diseases with periods of exacerbation. Not allowed to introduce the drug into a vein or into the subcutaneous fat due to possible serious complications of health. Diclofenac when used as serious diseases of bones and joints, but also in local pain transient nature. Injecting is advantageous and most effective method of arresting disease outbreak.

Contraindications include pregnancy and lactation (Unless otherwise indicated doctor) clinical history weighed which does not allow application of Diclofenac injection or in any other forms. All contraindications are taken into account on the basis of the doctor the patient's history and the nature of this symptom.

See also: Instructions and price Diclofenac

Features of the application

The use of Diclofenac injections is possible only after a full examination. procedures are often performed in a hospital environment due to the specific means of administration. With significant experience in patient self-administration of intramuscular preparations, let's treatment as an outpatient. Course duration and dose determined by the physician.

Diclofenac single dose per day is usually not more than 100 mg of base material. In the event of adverse events (adverse local and systemic reactions) prescribe alternative medications analogues to continue anti-inflammatory therapy.

Diclofenac injections made into the outer surface of the thigh or in the buttock region. adult for injections should be taken in 5 mL syringe. This optimum length of the needle syringe for safe administration. In formulating injections in the buttocks outline upper right quadrant. The hip enough to outline the area with a strained muscle.

In the application of Diclofenac in injections should be familiar with the instructions, be sure to consult with your doctor. If you are new injection sites should visit a medical office throughout the course. This is to avoid local and general serious complications.

sources:

Vidal: https://www.vidal.ru/drugs/diclofenak__11520
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 5d8a978b-56fd-4465-bfa0-907ab6103f33 & t =

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