Patients who have identified violations of carbohydrate metabolism, prescribe metformin for the prevention of diabetes. But on their own to start taking pills is impossible, it is important to pass the pre-tests, consult with an endocrinologist. Many use it as a means to combat obesity and the prevention of cardiovascular disease.
pharmacological features
Metformin is used for patients suffering from hyperglycemia. Under its influence stimulates the utilization of glucose by cells associated with insulin. This is achieved by reducing insulin resistance of the tissues. As a result of the drug level in the blood sugar dropping.
Use a pill can not only for the treatment of diabetes. Endocrinologists are often recommended for the prevention of metformin. Assign it to patients who showed abnormal carbohydrate metabolism, increased insulin resistance of tissues.
Reducing the concentration of glucose in patients with prediabetes leads not only to the fact that endocrine disease risk is greatly reduced. By reducing the sugar content of vascular condition ceases to deteriorate. Indeed, under the influence of elevated glucose concentrations, their walls become thinner and become more brittle. The regular use of metformin is considered to be the prevention of cardiovascular pathologies.
People who do not suffer from diabetes, but can not get rid of excess weight, start to metformin treatment for weight loss. Regular intake of the drug helps stop weight gain in some people starts to decrease body weight. But taking pills for obesity prevention is not necessary.
Metformin also affects the lipid metabolism. Under its effect begins to decrease the concentration of total cholesterol, triglyceride and low density lipoprotenov. Some argue that the prevention of aging of metformin can be carried out.
This effect is achieved due to the fact that under the influence of tablets:
- improving vascular condition, cardiac muscle;
- normalizes blood circulation, including the brain;
- reduced risk of cancer;
- 30-40% decreased likelihood of death from diabetes, stroke, heart attack.
Of course, Metformin is not a tool that prevents the senility. But by reducing the likelihood of dying from the most common causes, possible increase in life expectancy. Means not only prolongs life but also improves its quality.
Mode of application
For the prevention of diabetes, metformin is recommended to take a certain scheme endocrinologist. If specific recommendations were not, patients who have pre-diabetes have revealed, for the prevention appoint 1000-1700 mg per day. Said daily dose should be divided into 2 doses. This is necessary to reduce the risk of side effects from the digestive system.
With the development of non-insulin dependent type of diabetes the dosage is gradually increased until, until it begins to decrease the concentration of glucose in the bloodstream.
But it is necessary to begin treatment with metformin, provided that other methods of prevention of endocrine disorders do not give a positive result. Before an appointment Metformin for diabetes prevention, an endocrinologist must warn that the use of tablets without correction lifestyle may not give the desired result. The first patients have to reconsider the diet and increase physical activity.
sources:
Vidal: https://www.vidal.ru/drugs/metformin-5
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ac45cb5c-4394-42ca-8479-a60a7a67e0b0 & t =
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