Ibuprofen - a popular drug that is often recommended dentists, trauma specialists and other areas of medicine. In this regard, many patients are interested in how best to take Ibuprofen - before or after a meal. And think about it very well, since compliance with the conditions of use affects the therapeutic effect and reduces the risk of side reactions.
pharmacological properties
Ibuprofen - a representative of the non-steroidal anti-inflammatory drugs (NSAIDs). He anesthetic, relieves fever and inflammation. Its pharmacological properties are explained by the ability to inhibit the activity of an enzyme that is a precursor of prostaglandins. Namely, they are at the biochemical level the immediate cause of the pain, vasodilatation and appearance of heat sensation.
Ibuprofen after oral administration almost completely absorbed from the digestive tract. And if you combine the use of funds from the meal, the rate of absorption is slow, so it is important to know how to take the drug correctly. Intermediate metabolites chemical synthesis disintegrate and detoxified by the liver by 90%. The half-life is 2-3 hours. Ibuprofen is excreted mainly by the kidneys (80%), as well as through the rectum (20%).
testimony
Not all instruction is written as taking Ibuprofen - before eating or after, but it is always a list of indications for use:
- inflammatory processes of the musculoskeletal system (the defeat of small joints, ankylosing spondylitis, cartilage damage, gout);
- pain moderate (migraine, pain during menstruation, toothache, inflammation of the trigeminal nerve, myositis);
- fevers on a background of the common cold or infectious pathologies.
The preparation is intended for the temporary relief of symptoms (pain, inflammation at the time of use), but it does not address the root problem.
application
Ibuprofen is recommended for use inside the 12-year-olds. One tablet usually contains 200 mg of active substance. But to quickly feel relief allowed a single dose of 400 mg (2 tablets), which can be taken 3 times per day. Although in most cases the drug dosage per day should not exceed 600-800 mg.
See also: Instructions and price Ibuprofen
Ibuprofen is better to drink before a meal only once in the morning. This will contribute to a more rapid absorption of the drug, but it is necessary to drink it with plenty of clean water. Tea, coffee and juice in this case is not relevant. During the day, the rest of Ibuprofen taken after meals, to avoid the development of acute adverse reactions on the part of the digestive system and the hepatobiliary zone.
Contraindications
Ibuprofen should not be taken before a meal in patients with such diagnoses:
- healed peptic ulcer;
- the presence of H. pylori infection;
- chronic inflammatory degenerative changes in the stomach;
- chronic inflammatory disease of the small or large intestine.
Absolute contraindications for receiving Ibuprofen are:
- allergies to components of the drug or any other NSAIDs;
- worsening ulcers;
- acute inflammatory processes in the gut;
- diseases of the hematopoietic system;
- after recent coronary artery bypass surgery;
- internal bleeding;
- severe hepatic or renal failure;
- period of gestation of the child;
- Pediatric up to 6 years.
The tablets can be easily obtained at a pharmacy without a prescription, but you should not forget that it is better to carry out the reception of the drug in the lowest effective doses. The lower the duration of the therapeutic course - the lower the chances of developing any side effects.
sources:
Vidal: https://www.vidal.ru/drugs/ibuprofen__11526
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 8f0e5ee3-ab17-46f0-b0b2-3e6d90e259a4 & t =
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