Rimantadine and Arbidol - agents used during the seasonal incidence of respiratory viral infections. Many patients ask what drugs are effective and that better Remantadin or Arbidol. Suffice it difficult to isolate some of the substances, the more effective because it depends on the individual human body. Let's do a comparison and try to figure out what's the difference Arbidol and rimantadine.
As the influence of drugs
Rimantadine is an antiviral agent that blocks viral replication at the early stage, exhibits activity against the pathogen influenza type A and arboviruses causing tick-borne encephalitis.
Arbidol (umifenovir active agent) blocked mergers and the plasmatic lipid envelope virus that promotes its destruction. The drug stimulates immune activity of the unit, causing the production of interferon and improves phagocytes.
In some situations, you can use drugs
If we compare Arbidol and Rimantadine, it becomes clear that they have not only a different mechanism of action, but they differ and indications for use. Common in the two medications is that they are used for the treatment of influenza virus type A.
Admission Arbidola justified under the following circumstances:
- for prophylactic therapy, and treatment of respiratory infections and influenza (type A and B);
- In the treatment of rotavirus infection of the intestine;
- chronic infectious-inflammatory processes of the lower respiratory tract;
- for the treatment of herpes;
- during the prevention of complications after surgery.
Rimantadine is appointed:
- prevention and treatment of influenza;
- prevention of encephalitis (viral) caused by tick bite.
Restrictions on the use of
Rimantadine is contraindicated in:
- for violations of liver and kidney functions acute nature;
- with hyperthyroidism;
- during pregnancy;
- hypersensitivity agent components.
Arbidol is not allowed to use:
- in case of hypersensitivity to the drug composition.
The difference between rimantadine and Arbidol not only in that the latter means is a much smaller list of contraindications. It should be noted that Arbidol approved for use in children from two years old and in pregnancy, whereas Remantadin can only accept children over 7 years and is contraindicated in patients hatched fetus.
dosage form
Arbidol made Russian pharmaceutical company Pharmstandard-Leksredstva. For the convenience of the consumer product produced in various forms: in the form of capsules umifenovir concentration of 100 and 200 mg Tablets - 50 mg powder for slurry - 25 mg.
Release of rimantadine is made by several companies: Russian - Rozfarm and CNN. Si.farm and Lithuanian - OlainFarm in tablet form, at a concentration of 50 mg of active substance.
It is worth noting that the cost of rimantadine in pharmacy slightly cheaper Arbidol.
How to use tools
Reception and rimantadine Arbidol for treatment of viral infections in children and adults is recommended to start in the first days of the disease, it will allow to maximize the effectiveness of resources.
Arbidol
For Arbidola single dose for adults is 200 mg, for children 6 to 12 years - 100 mg, for children from 2 to 6 years - 50 mg.
The treatment regimen is as follows:
- for the prevention of influenza and respiratory infections - 1 dose twice a week with a duration of 14 days;
- after exposure - 1 1 dose once a day for 10 -14 hours;
- SARS and influenza therapy - 1 dose four times a day for 5 days;
- rotavirus intestinal infection - 1 dose four times a day for 5 days;
- treatment of viral infections of the respiratory tract and herpes - 1 dose four times a day for 5 - 7 days after 1 dose required receiving twice a week for 30 days;
- prevention of complications after surgery - 1 dose two days before the operation and 1 dose of 5 and 7 days after the intervention.
In young patients can be taken instead of Arbidol rimantadine for the prevention and treatment of influenza and acute respiratory viral infections. Since this tool is authorized for use in pediatric patients at an earlier age.
rimantadine
Application should be carried rimantadine postprandial follows:
- 1 day 100 mg three times a day or 300 mg odnorazovo;
- 2 - 3 day 100 mg twice a day;
- Day 4 100 mg once a day.
Children 7 - 10 years of age should take 50 mg twice daily, 11 - 14 years 50 mg three times per day, duration of treatment - 5 days.
For the prevention of use of 50 mg of rimantadine one-time a day for 10 - 15 days.
When the tick bite - 100 mg twice a day during 3 days after the bite.
therapy Features
Rimantadine is used under medical supervision in patients with hypertension, because during the course of therapy may increase the disease.
Also with special caution should be treated in patients with a history of epileptic manifestations. In this case, the drug may increase the risk of seizure.
If the reception of Arbidol and rimantadine has been passed, it is recommended to take the medication as soon as possible and continue to carry out treatment, according to the regimen prescribed by your doctor.
Instructions to the described means contains no restrictions to the complex therapy more antiviral agents. This means that you can take Arbidol with rimantadine, because drugs have a different mechanism of action. However, such use should take place only after consultation with a specialist.
Side effects
In the following negative symptoms may occur during therapy rimantadine:
- allergic reactions;
- pain in the epigastric region;
- flatulence;
- mucous dryness sensation in the oral cavity;
- nausea;
- retching;
- increasing the concentration of bilirubin;
- headache;
- sleep disturbance;
- irritability and nervousness;
- feelings of anxiety and fatigue.
Receiving Arbidol may cause allergic reactions, in particular redness, rash and itching.
In the event of negative manifestations of side effects, as well as any other uncomfortable conditions during Arbidol and rimantadine therapy is recommended to interrupt the reception means and seek the advice of the attending doctor. In this case, you change the treatment regimen, or the replacement of analogue rimantadine or Arbidol example Kagocel or Citovir.
conclusion
The seasonal increase in the incidence of respiratory viral infections and influenza among the most essential drugs are antiviral agents. It is to this list include Rimantadine and Arbidol. Medications given the opportunity to prevent illness and cure it in short order. A very important point is that both drugs can reduce the possibility of developing complications from the disease.
The question many patients it is possible to simultaneously drink Arbidol and Rimantadine, the answer is yes. However, before such a comprehensive therapy you should consult with your doctor. Since this combination can increase the load on the body and cause a variety of negative developments, especially in patients with chronic diseases.
sources:
Vidal: https://www.vidal.ru/drugs/arbidol__3331
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 4acb4889-e69e-4a5c-8637-ce1bc03caabd & t =
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