Ibuprofen - nonsteroidal anti-inflammatory drug, which copes with pain relief at:
- inflammation of the joints;
- head pain;
- toothache;
- heat and chill;
- neuralgia and others.
Despite the fact that ibuprofen is similar to paracetamol, to him still have some questions. So how dangerous Ibuprofen?
Is Ibuprofen increases the likelihood of a heart attack?
Even in 2013, one European magazine issued a shocking story that some painkillers, which are wildly popular (Ibuprofen entered in the list), increase the likelihood of developing cardiovascular ailments. After such a statement, British scientists have done a great job and found that indeed, the harm of Ibuprofen in large quantities is possible. They have proven that taking Ibuprofen can be dangerous in overdose drug over 2400 mg per day. It is the use of the drug in such quantities increases the likelihood of heart attack by 30%. Therefore, patients with "weak" heart is not necessary to self-medicate with this substance.
A little later, scientists from America have also shown that ibuprofen keeps the human body salt and water, which in turn It neutralizes all the work of diuretic medications to normalize blood pressure and cause heart failure.
Ibuprofen and impotence: What is the relationship?
In 2011, one of the organizations article was written in the states that men who took ibuprofen for 3 months, three times a day, to increase the "chances" to become impotent.
After a series of studies side effects were confirmed. But, it is not necessary to refer to this fact too scrupulous, because symptomatically in small doses Ibuprofen is not harmful, and less dangerous means you can pick up for chronic illnesses.
See also: Instructions to the drug Ibuprofen
Is it possible to use ibuprofen during pregnancy?
Despite these risks, Ibuprofen can also be dangerous during pregnancy. Guide to the preparation states that the use of ibuprofen is dangerous for the child, because the can provoke the development of cryptorchidism (risk increases 16 times in boys).
This Danish scientists proven fact reported in 2010. After monitoring the course of pregnancy in more than 1,500 expectant mothers, who often abused analgesics was it is clear that after a couple of months after a combination of the two drugs significantly the risk of such diseases increased.
Most unforeseen consequences may be if you take the medication during the first trimester of pregnancy. It was on this term Ibuprofen (as well as other analgesics) reduces the production of testosterone, which leads to incorrect and defective development of male reproductive organs. If this disease is not treated in a timely manner, in adulthood, it can result in infertility.
Is it possible to combine ibuprofen with other medicines?
Sometimes the benefit or harm of the treatment depends on the correct combination of different drugs, especially if the patient appoint them in large quantities. This ibuprofen is not very lucky, because it is not combined with a great list of the most popular drugs.
Ibuprofen is not dangerous in case of failure of the use of the following medications:
- Drugs that lower blood pressure;
Ibuprofen may be provocateur upper pressure increase in patients who take ACE inhibitors and other antihypertensive agents.
- Analgesic and antiinflammatory substances;
To avoid the development or aggravation of gastrointestinal diseases and the likelihood of bleeding, while taking Ibuprofen should not take diclofenac, naproxen and similar drugs.
- aspirin;
Simultaneous use of ibuprofen with aspirin increases the likelihood of bleeding opening, because both have a diluting effect of the drug. It is absolutely contraindicated to take Ibuprofen for people who have poor blood clotting.
- digoxin;
Typically, this preparation is prescribed as a therapy for arrhythmia. But if his use add Ibuprofen, the probability of overdose, which in turn can cause vomiting, indigestion, intestinal necrosis, tachycardia, and even mental disorders.
- lithium;
Such a preparation is mainly discharged patients who are suffering from mental disorders. Ibuprofen, unlike Li, is not dangerous for man, but the combination of these two drugs impairs removal of metal the human body, the accumulation of which in excessive amounts threatening intoxication, irreversible destruction of the central the nervous system. In more complicated cases may be fatal.
- methotrexate;
This substance is used to treat cancer patients and patients with autoimmune diseases. The combination of ibuprofen with it has the same effect as the combination of ibuprofen with lithium, after there is an accumulation of matter, which leads to the irreversible destruction of liver and undesired hematopoietic system.
- Antidepressants.
The combination of various antidepressants Ibuprofen can cause bleeding opening.
sources:
Vidal: https://www.vidal.ru/drugs/ibuprofen__11526
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 8f0e5ee3-ab17-46f0-b0b2-3e6d90e259a4 & t =
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