Flemoksin Soljutab - is an effective modern antibiotics, which is used to treat a variety of bacterial lesions. In its application it is important to present a complete picture of its action, the peaks in blood levels, and how many removed from the body Flemoksin Soljutab.
Efficiency flemoksin
The preparation of extensive influence on the basis of amoxicillin is used to treat diseases caused by pathogenic microorganisms:
- streptococci;
- stafillakokkami et al.
Taking it possible for children and adults. Specially developed the active form of the drug allows the active substance is well absorbed through the digestive organs. It is not necessary to separate the reception of funds from the time of food, as its presence does not affect the absorption.
Resistance to acid makes the drug particularly effective - absorbed through the gastrointestinal tract at least 93%. Peak blood concentration of amoxicillin reached after 60 - 120 minutes after ingestion. This is significantly higher than the treatment means on the basis of the same active ingredient, which do not dissolve in water. For ease of administration, tablets can be diluted and drinking drug as a suspension. Flemoksin excreted through the kidneys.
Use of the drug is indicated for lesions of infectious bacterial nature:
- leather;
- gastrointestinal;
- Urinary tract;
- the soft tissues;
- the reproductive system;
- respiratory system.
Used to treat Flemoksin only on prescription, in accordance with the instructions supplied with the tablets. If the recommended dose is not exceeded, then the drug is well tolerated and has a therapeutic effectiveness, as evidenced by the responses of patients.
Accumulation and excretion of the drug
When injected into the GIT Flemoksin does not unduly influence the mucosal aggressive. Good ability to accumulation allows you to find the drug in therapeutic amounts of mucous, sputum, intraocular fluid, bone. One-fifth of amoxicillin associated with blood plasma. The bile concentration significantly higher than in the blood - from 2 to 4 times.
Part of the active ingredient metabolized. Flemoksin exits the body through the kidney: 1/5 - glomerular filtration, the rest - kanltsevoy excretion.
After 8 hours after administration, about 90% of the drug is excreted predominantly in the urine. How quickly Flemoksin completely eliminated from the body, it depends on the work of the kidneys. In this case, the liver pathology at the rate of elimination is not affected. Half-life of the active substance in the absence of disturbances and a half hours, the child of the first six months of life - from 3 to 4. When malfunction renal elimination half-life may be substantially greater - up to 8.5 hours at anuria.
Some medicines used together with Flemoksin can significantly slow elimination of the drug from the body. Some of these medications include:
- sulfnpirazol;
- aspirin;
- oxyphenbutazone;
- phenylbutazone;
- probenecid.
Thus there is an increase in the concentration of active substance in the blood. In addition, the drug may not be mixed with alcohol. When co-administered antibiotic effectiveness is reduced and pathogenic microflora receives resistance to penicillin drugs group.
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