Components and shape medication
Pancreatin is sold in tablet form. The polymer bottle released 60 pieces in blister pack - ten. Per tablet accounts for 30 action units - units - protease.
Also can be purchased in pharmacies Pancreatin Forte. It contains amylase - 4620 IU lipase - 3850 units, the protease - 275-500 IU. The polymer is sold bank 20, 30 or 60 tablets in blister - 10. As part of the formative components have starch.
medicinal properties
Pancreatin - a drug that is able to replace the pancreatic secretion. As part of the preparation contains digestive enzymes. They are necessary for the digestion of peptides, lipids, and carbohydrates coming from the food.
In tablets, Pancreatin contains:
- amylase - degrading enzyme glycogen and starch;
- Lipase - an enzyme that performs the function of the catalyst during dissolution and digestion of lipids;
- protease - a proteolytic enzyme involved in the breakdown of protein molecules.
These enzymes may be sold separately, and if the patient has only one disadvantage of digestive substances. But for complex problems with the digestive tract needs a full set of the most important enzymes.
These active ingredients facilitate the assimilation of peptides, fats and carbohydrates. Recent best absorbed in the small intestine after digestion.
Medicine compensates for the lack of enzymes in many pathologies. Especially very good for secretory pancreatic diseases. Typically, the selection of enzymes for the digestion of food - it is the work of the pancreas, but for pancreatitis and other gastrointestinal pathologies exocrine function is reduced.
When the drug is administered
The gastroenterologist may appoint drink Pancreatin in such cases:
- cystic fibrosis, chronic form of pancreatitis and other diseases with impaired secretion of body;
- remission of gastrointestinal pathologies;
- chronic diseases of the hepatobiliary system;
- resection of the intestine or irradiation, followed by diarrhea disorders;
- Preparation for instrumental examination.
The drug is equally effective and inflammatory, and atrophic diseases of the stomach, if they are associated with poor digestion.
Taking the drug can be episodic and digestive disorders. For example, in the use of unusual food, flatulence, disorder of the stomach.
Contraindications
you can not take medicine when acute pancreatitis. After elimination of recurrence and transition into a stable remission, the reception can be continued on the advice of a doctor. Do not take if there are episodes of allergy to the drug in the history of the disease.
Safety during pregnancy and for children
Pregnant Pancreatin can be displayed due to prolonged gastrointestinal diseases, which appeared before pregnancy. Also, the drug is advised for women with disorders that occur during pregnancy itself. In this case, receiving episodic, as needed.
Manufacturer of the drug did not carry out formal safety studies in pregnancy. Expectant mother is allowed to take during pregnancy Pancreatin, if use will prevail over possible harm.
Later we held clinical experimental studies. Under steady-state conditions for women during pregnancy administered Pancreatin to eliminate the symptoms of dyspeptic disorders. As a result of receiving the child was not injured, and the drug had no effect on pregnancy.
In children, the drug is prescribed with individual dosage calculation. Sometimes the drug causes constipation in children because of the lipase content in the rest of Pancreatin - a drug with a high safety profile.
Pregnancy and digestive problems
During pregnancy there are major hormonal changes, such as increased levels of progesterone. The greater the gestational age, the higher the concentration of this hormone. It is designed to prepare the body for childbirth and prevent premature uterine contractions.
But the hormone does not act selectively. Gastrointestinal organs also are lined with smooth muscles - it is responsible for peristalsis and motility, movement of food through the intestines. Reduced muscle activity provokes stagnation. Food does not move, begins the process of fermentation, a woman suffering from constipation.
Condition is dangerous because of the intestine into the bloodstream absorbed toxins formed by the stagnation of feces. General intoxication of the organism is not conducive to the healthy development of the child.
Another problem - it heartburn and acid regurgitation. They provoked the weakening of the lower esophageal sphincter. Stomach contents into the esophagus lying, damaging the mucous membranes. With these problems in pregnant women face already in the early stages.
From the second trimester of pregnancy added another gastrointestinal disorder work factor. The uterus and the fetus increases in size. They may compress the intestine and stomach, causing gastric casting mass into the esophagus.
Efficacy in pregnancy
In pregnancy, the main factors are digestive disorders:
- pressure on the stomach and intestines;
- weakening of smooth muscle;
- slowdown in motor and motility;
- exacerbation of chronic pathologies.
Another factor might be changes in the taste preferences, unusual combination products. But these disorders are immediately after the normalization of the diet.
In some cases, Pancreatin for pregnant it would be appropriate:
- digestion disrupted as a result of unusual food;
- in the treatment of constipation and decreased motility;
- with abdominal discomfort, belching, heartburn.
Pancreatin solve the problem of reduced motility of the digestive tract and will work harder in pregnancy. This is to prevent constipation in the future, eliminate stagnation, and with them, heartburn and sour burps, possible pregnancy. But it is necessary to understand that Pancreatin not help to gently cleanse the bowel of already formed and stagnant masses. To do this, the doctor will prescribe laxatives permitted during pregnancy.
If the problem only in high acidity, Pancreatin it will not eliminate. To do this, antacids, officially tested for safety during pregnancy. But in chronic pancreatitis, which has been exacerbated during pregnancy, Pancreatin is irreplaceable. He will improve bowel function and prevent constipation, epigastric pain and nausea.
Rules of application and dosage
When early pregnancy Pancreatin taken only under medical supervision. If there are already complaints of constipation, you must first take steps to cleanse the intestines measures, and only then take Pancreatin.
Dosage during pregnancy depends on the severity of the lack of enzymes. The average daily dosage for an adult - 150 000 units. If the pancreas does not produce the enzyme, a day is prescribed 400 000 units of lipase - is the daily level of need for adults.
The maximum dose - 15 000 units per kilogram of body weight. The duration of treatment in pregnancy depends on the nature of the violation. If a digestive disorder caused by improper diet, treatment of pancreatin lasts from one to three days. If it is required replacement therapy, reception may last for years.
Take with food or immediately after meals. Crush the tablet is not needed. Wash down with water only, at least one cup.
Features of the application
During pregnancy in 1 trimester drinking Pancreatin should be started only under medical supervision. If the organism is a normal response, and the drug will show therapeutic efficacy, reception continues in the outpatient setting with periodic consultation of the gastroenterologist and obstetrician.
It is important to remember that prolonged constipation and intestinal obstruction during pregnancy may appear intestinal strictures - stretching. It is necessary to control the symptoms and to seek help if the condition worsens.
Recommended levels of acid in the urine of control to prevent the formation of stones during pregnancy. Pancreatin contains enzymes high activity. Therefore, the tablet must be swallowed whole, not chewed in the mouth, that it is not damaged mucous membranes.
If Pancreatin during pregnancy need to take all the time necessary to take care of the replenishment of iron stores in the body. Assign vitamins and minerals.
To wash down the medication is best alkaline liquids. For example, alkaline mineral water or 1% solution of baking soda in the absence of contraindications.
Adverse reactions
If pregnant women taking Pancreatin for therapeutic dosages, side effects develop less than 1% of patients.
There may be such undesirable reactions:
- constipation;
- abdominal discomfort;
- diarrhea;
- nausea, feeling of heaviness.
One can not say that these reactions provoked by intake of pancreatin as similar symptoms and is accompanied by diseases of the gastrointestinal tract.
Allergic skin rash appears. Intolerance to the drug, discontinue use and immediately go to the doctor - allergy during pregnancy can be dangerous.
Prolonged use of large amounts may increase the level of uric acid in the blood. The children found the irritation of the anal area.
Overdose
Symptoms of an overdose of pancreatin:
- abdominal discomfort;
- constipation;
- detection of high concentrations of uric acid in the blood;
- high acidity of urine.
In children and rarely in adults overdose accompanied by perianal irritation - itching and burning in the anal area.
To eliminate symptoms of an overdose need to stop taking the drug. It is recommended to drink plenty of water, the treatment is symptomatic.
drug interactions
During pregnancy, the list of drugs that are safe for mother and child, is extremely limited. Only a specialist should decide what you can drink Pancreatin pregnant, to treat and prevent constipation and frustration in the future.
Efficacy pancreatin decreases in parallel with the reception of antacids containing alkaline earth metals. Supplementation is necessary to differentiate with respect to time. If your doctor has prescribed during pregnancy to drink iron supplements, they also need to be taken two hours before or after taking pancreatin.
You should not start taking pancreatin alone, expecting a baby. Even if before the Pancreatin was well tolerated during pregnancy, it can trigger unpredictable reactions.
sources:
Vidal: https://www.vidal.ru/drugs/pancreatin__25404
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 43524e11-4cf0-40a9-8931-ed1ef8c746b3 & t =
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