Nurofen - is a preparation from the group of nonsteroidal anti-inflammatory drugs (NSAIDs). According to the instructions, it is often used as an analgesic, hypothermic agent. Nurofen during pregnancy in 1 trimester should be used very carefully, and it is better to do without him. The medicine can cause pathology of the fetus in early pregnancy, and also cause miscarriage and premature birth in the later stages of gestation.
Shape and properties of the drug, indications, limitations
Nurofen produced in several forms: cream, gel, tablet, suspension (syrup). Tablets produced 200 mg Ibuprofen. In 5 ml of the suspension has a 100 mg drug substance. The gel contains 5 g Ibuprofen 100 g of finished material.
Properties Nurofen:
- relieves inflammation;
- reduces the intensity of pain;
- providing hypothermic effect through inhibition of prostaglandin synthesis.
Limitations to the use of |
side effects |
|
· 3 trimester of pregnancy; · Ulcerative disease of the digestive tract; · Liver and kidney disease; · High blood pressure; · Pathology of blood coagulation. |
· Worsening of ulcerative colitis, stomach ulcers; · Bronchial asthma (Aspirin); · Allergy; · Dyspeptic symptoms; · Kidney liver dysfunction. |
Use in pregnancy
Pregnancy requires that women and doctors a lot of attention. At different stages of gestation in a woman's hormonal changes, which determines the normal fetal growth and development.
During pregnancy (before 12 weeks), there is the main tab organs and systems of the fetus. 3-4 weeks formed the neural tube, the heart. At later stages of developing sexual organs of the fetus, lungs, liver, kidneys. By 12 weeks the placenta begins to form. It protects the baby from toxic substances that enter the mother's blood.
Take Nurofen during the first trimester of pregnancy is not necessary even in the presence of placenta formed as Nurofen crosses the placental barrier. There is evidence that ibuprofen can cause genital malformations and cardiovascular system.
In inflammatory diseases of the musculoskeletal system (as an anesthetic) and physicians may assign fever drink drug at 200 mg up to 4 times per day. Drink preparation in 1 trimester of pregnancy should be only if the benefits exceed the risk of life for the child.
In one trimester Nurofen administered in the form of an ointment, gel or syrup. Child syrup has a concentration of the substance smaller than tablets, therefore avoiding overdosing and reduce the likelihood of side effects.
Ibuprofen is allowed to use in the second trimester of pregnancy. During the third trimester, the drug is contraindicated, as capable of provoking tone of the uterus (fetal hypoxia), birth prematurely, postmaturity fetal pathology of the interventricular septum.
conclusion
Nurofen in the first trimester of pregnancy is best not to use, as the drug penetrates well into the placenta and the fetus is broken. When an allergic response, bronchoconstriction, uterine or gastric bleeding is necessary to urgently stop the woman taking the drug and to contact the attending physician. Independently take ibuprofen during the entire period of gestation is not necessary.
sources:
Vidal: https://www.vidal.ru/drugs/nurofen
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ea36b816-80ee-4545-91a0-e65253aa27a3 & t =
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