General characteristics of the composition of Panthenol
The active substance is dexpanthenol means. One gram of the ointment it contains approximately 50 mg. Among the additional components glycerol recovered. Its concentration reaches 85%. Also medicine contains white paraffin, light mineral oil, a little alcohol and distilled water. In pregnancy, the components are safe.
If the agent as a spray, the ratio of different components, as the composition as a whole. 100g of therapeutic foam contained 4.63 mg of active ingredient. There are also additional ingredients. Among them emulsification cetostearyl alcohol. In addition, it contains oil, wax and liquid propellant. During pregnancy, use Panthenol recommend in any form.
Pharmacodynamic properties Panthenol
The drug belongs to the group of medicines which promote healing of ulcers, wounds and minor damage. Dexpanthenol is a provitamin B5. It has the same potency and efficacy as such substance as pantothenic acid.
When applied to the skin surface panthenol, means active substance is transformed to form pantothenate. This compound, like its salts are water-soluble vitamins. They are in the form of coenzyme A is actively involved in metabolic processes. Due to these effects used by pregnant Panthenol often advised.
The pharmacokinetic characteristics of
The pharmacokinetics of the drug describes how Panthenol behaves in the human body. When applying the drug active ingredient is rapidly absorbed by the skin. After that, there is a transformation in pantothenate, which is added to the depot of this vitamin.
With the penetration of active ingredients into the blood Panthenol, it is their binding to proteins. Advantageously albumin and β-globulin. In healthy patients, the concentration of the substance is equal to 500-1000 mg / l in the blood. If you apply Panthenol during pregnancy, there may be other factors. But it is not considered a violation.
Pantothenic acid undergoes metabolism in the body. Its elimination is carried out in an unmodified form.
Indications for use Panthenol
Application means a woman during pregnancy must be justified. You can not use it on their own and without an appointment by his doctor. The use of drugs is only permitted after consultation, and if the benefits from the use of more than the risk of the consequences if Panthenol use during pregnancy.
Among the most common indications for use of the means in an ointment such isolated:
- preventing skin dryness;
- treatment of cracks and peeling of the skin;
- Warning manifestations of irritation;
- burns;
- minor injuries;
- ulcerative defects with a chronic course;
- anal fissure;
- erosive damage to the endometrium;
- recovery period after skin grafting.
During pregnancy ointment Panthenol often used to treat cracks and irritation on the nipple. Also, it is necessary for lactating mothers during lactation.
During pregnancy increases the need for Panthenol. This is due to the fact that the carrying of the baby changing hormones. This, in turn, provides a change of metabolic processes. This increases the manifestations of dry skin, deteriorates for diseases associated with ulcers and erosions.
Panthenol Spray is increasingly used for the treatment of dermatitis and dryness events. But the main indication are small wounds, burns and abrasions.
Features of the application of panthenol and dosage
During pregnancy, should be careful to use panthenol. First of all, we should observe an adequate dosage. To accelerate the healing of wounds and fractures small enough to apply about 1-2 grams (depending on the lesion area) once a day.
For the treatment of defects in the mucosa of the uterus of the same amount sufficient therapeutic ointment. For the healing of cracks on the breasts in women during lactation it is recommended to apply the minimum dose means after each nursing.
If you use a spray, especially during pregnancy, it is important to remember that before applying the spray should be well shaken. Do not apply it directly on your face. If necessary, better to spray on your face and rub into the wound site.
How to use during pregnancy
The use of drugs is permitted during pregnancy. But women should be as cautious. It is important that pantothenic acid has the ability to penetrate through the placental barrier.
This is done using special active transport mechanism. For lactating women it is important to remember that milk is allocated the amount of active substance, which is proportional to its absorption. It is therefore important in the appointment of Panthenol during pregnancy into account, as the potential benefits and dangers.
Contraindications, side effects and overdosage
Contraindications to the use of drugs, virtually none. But Pantelol in the form of ointment, and spray can not be used in case of individual intolerance of any of the funds components. This is especially dangerous during pregnancy.
Side adverse events are rare, even during pregnancy. Usually they appear as minor changes in the immune system and the skin. The immune system reacts to the development of allergies Panthenol. Most often it is characterized by dermatitis, erythema, eczema, urticaria, rash sometimes in the form of small bubbles.
The advantage of tools for use in pregnancy is no toxic effect. Another important feature is that the overdose is not developed.
analogs
List substitutes a small drug. As the active agent is isolated so popular analogue as Bepanten. Its effect is the same, the composition is also similar. But the release form - an ointment, cream and lotion. It is also common means Pantekrem ointment, Panteksol, Dekspanten.
If the patient is more convenient to use medications for spraying, you can buy Depantol in aerosol spray Panteksol. In addition, good medicine believe Heppiderm in an aerosol form and cream. Analogs not effective and all are allowed during pregnancy, but have significant differences in price.
conclusion
Treatment not only common ailments, but also skin lesions, requires a responsible attitude. Especially it should be considered if necessary to apply Panthenol in early pregnancy. During this period, the doctor should monitor the patient's health condition. In the event of even the slightest infringement, should abolish the use of panthenol, so as not to complicate pregnancy.
sources:
Vidal: https://www.vidal.ru/drugs/panthenol
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 00a29f41-eba7-41b0-90b7-14d320dca665 & t =
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