Duspatalin and No-Spa includes a group myotropic antispasmodic drugs. These medications are used to relieve the pain of various etiologies. Many patients would like to know what is best No-Spa or Duspatalin. Let's try to understand how these substances.
The active substance is shpy drotaverin, which blocks the enzyme phosphodiesterase, thereby increasing the concentration of cyclic AMP, which causes relaxation of smooth muscles.
Mebeverin - Duspatalin active substance acts at the smooth muscles of the digestive tract (mainly in the large intestine), removing a spasm. The drug has no effect on the motility and inhibits acetylcholine receptors.
Both products have a relaxing effect on smooth muscle. Therefore, to determine which of the drugs is better on this parameter is not possible.
When prescribers
No-Spa Duspatalin different indications for use. It covers a wider range of pathologies.
Nospanum prescribed in the following situations:
- spasms of smooth muscle, caused by diseases of bile duct;
- spasms of smooth muscle of the urinary tract;
- spasms, which cause disorders gastrointestinal functions;
- headache;
- pain during menstruation.
Duspatalin apply:
- spasm in the digestive track;
- intestinal colic and biliary type;
- in spastic colitis (irritable bowel syndrome);
- with painful sensations, due to impaired gastrointestinal function.
It should be noted that in pancreatitis Duspatalin and No-Spa are assigned to eliminate pain in combination with other drugs. The dosage and duration of the course in this case, the appointed doctor individually, depending on how the disease occurs.
When should limit the use of drugs
Duspatalin not indicated for therapy with a history of hypersensitivity to the composition of the patient's medication.
No-Spa is forbidden to use:
- at povyshenenoy sensitivity to komponenitam means;
- in violation of the functional activity of the liver and kidneys in severe;
- with severe cardiac disorders, particularly for low cardiac output syndrome.
The drug should be used with extreme care in the propensity to hypotension.
As we can see, the difference between Ho-Shpoy and Duspatalin in significant limitations to the use. Another difference is the minimum age at which permitted these medications. Nospanum can take children from 6 years of age, but Duspatalin allowed to eat only 12 years old. In pediatrics for the replacement of these muscle relaxants are most often used their counterparts - papaverine or trimedat.
Features
No-Spa is made in the form of tablets and solution for parenteral administration, it is yet another difference between the drugs as Duspatalin can only be purchased in capsules and tablets.
Both medicinal agents may cause side effects, lead to allergic reactions and vertigo. However, No-Spa may further provoke cardiac arrhythmias. And an overdose of this drug can cause fatal consequences. That is why taking together Duspatalin and Nospanum not recommended, as the funds are part of a group of medicines and their co-administration may cause negative effects of an overdose.
conclusion
Duspatalin and No-Spa antispasmodics exhibit properties against smooth muscle. Preparations well help eliminate cramps and pain. And to understand which of the two resources better, it is difficult, because the body of each person is different. When you select should bear in mind that the No-Spa has more limitations and adverse events. However, it should be noted that the No-Spa is a cheaper medication, compared with Duspatalin.
Duspatalin eat at the same time and no-silos - is dangerous. Sharing of medical devices can cause development of negative effects of overdose and lead to serious consequences.
sources:
Vidal: https://www.vidal.ru/drugs/duspatalin__33504
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 55cd07f4-f26a-48af-a082-3bcea9f6d970 & t =
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