Mydocalm is pharmacological agents used as a muscle relaxant. It relieves spasm of striated skeletal muscle. In appointing the drug patients are interested in: increases or decreases the pressure Mydocalm. A drug widely used to treat multiple sclerosis, post-stroke condition, with muscle spasms in patients in the postoperative period, as well as joint diseases, cerebral palsy spastic type, osteochondrosis.
The composition, shape, indications, limitations to the purpose, pharmacological properties, the use of
Mydocalm produced by pharmaceutical companies in the form of tablets and ampoules. Active drug component is tolperisone hydrochloride. Tablet dosage forms are of 50 and 150 mg. The vials (1 ml) contains 100 mg tolperisone hydrochloride, 2.5 mg of lidocaine hydrochloride (for injections).
Tolperisone hydrochloride - central muscle relaxant. The drug helps stabilize the membranes of nerve cells, reduces conduction of nerve fibers, blocks the flow of potassium ions through the membrane. Preparation improves blood flow of the peripheral blood vessels impedes the work adrenoceptor reducing muscle spasm of vessels in the periphery.
The drug is metabolized in the kidneys, liver, appears in the form of metabolites through the urinary system, as well as bile. Maximum blood concentration is reached after 30-40 minutes when parenterally administered substance. tolperisone hydrochloride readily crosses the placenta into the brain. The half-life time was 1.5 hours.
Indications and limitations to the purpose Mydocalm
testimony |
restrictions |
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heightened tone of skeletal muscle spasm or with a central nervous system diseases (CNS) (multiple sclerosis, myelopathy, postinsult, damage to pyramidal structures of the brain); disease of the articular system, accompanied by strong muscle spasms, contractures (spondylarthritis, arthrosis); postoperative period after surgery; obliterative vascular disease (diabetes angiopathy, Raynaud's disease, scleroderma); poor innervation of the vascular bed; cerebral palsy spastic origin, as well as other CNS diseases involving violation of muscle tone. |
drug intolerance, as well as Lidocaine (for parenteral administration); Children up to age 3 years (tablet) to 18 years (vials); myasthenia gravis; pregnancy; lactation. |
Adults should take the drug at 150-450 mg, the daily dose is divided into 3 doses. Children 6 to 14 years administer daily 2.4 mg / kg body weight, daily dosage is divided into three portions. In pediatric tablet form appropriate to use 50 mg Mydocalm. Serving medicine better postprandial washed down with 20 ml of water. Injections are shown only adult patients 1 ml twice per day when administered intramuscularly 1 ml dose (i.v.).
Undesirable effects:
- muscle weakness;
- pain in the head;
- pressure reduction below normal levels;
- dyspeptic symptoms (nausea, vomiting, abdominal discomfort).
Receiving adequate dosages practically does not cause unwanted effects.
The impact of drugs on the pressure
Do Mydocalm increases the pressure? According to the official statement, drug helps lower blood pressure (BP). Most often it is due to receive larger doses of the drug. Raise pressure Mydocalm not work, since the mechanism of drug is vasodilatation, resulting in reduced pressure. The drug is not included in the comprehensive treatment of hypertension.
Mydocalm lower pressure can be at a bolus (fast) introduction of medicament vein. This can lead to loss of consciousness. To normalize blood pressure and improve blood supply to the head of administration of the drug is necessary to stop the influx, lift the patient's legs on a pillow. If the measures do not help, then enter a drug that increases blood pressure or to hold saline infusion therapy (Ringer's solution) to reduce the concentration of the drug in the blood.
conclusion
Mydocalm use only prescribed by a doctor prior to use to read the instruction. When drinking Mydocalm pressure (hypertension) can be. Do not appoint Mydocalm patients with hypotension (low pressure). Children under 3 years of drug use if the benefits outweigh the harm (on doctor's orders).
sources:
Vidal: https://www.vidal.ru/drugs/mydocalm__31619
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7d7d4f70-ea02-447f-b964-2ef987a6e9ac & t =
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