Even with the most careful preparation for pregnancy can not exclude infection with herpes or exacerbation of existing infection. Since there is no 100% guarantee, sometimes it is necessary to solve the problem, take acyclovir during pregnancy in the 2nd trimester, with the purpose of treatment or not. Well, when a woman before conception had already been confronted with herpes - in this case it already has antibodies that can in some way to protect her and limited to low doses of medication.
Mechanism of action
The principle of action of the drug based on its ability to interrupt the viral DNA synthesis. This leads to the fact that the virus is no longer multiply and into remission. Unfortunately, the active compound preparation is capable of penetrating through the barrier between the placental barrier and into breast milk. This fact limits the use of the drug in pregnant women.
The manual does not say exactly whether the drug acyclovir during pregnancy to take - only in general terms about what to weigh the risk to the child and the potential benefit to the mother.
Indications for use
Assign this tool can be in the following cases:
- with cold sores on the face (lips and under the nose);
- at defeat mucous genitals;
- during the treatment of herpes zoster;
- for the prevention of herpes infection.
In each case requires individual approach for the treatment of manifestations of herpes expressed during pregnancy should be preferred to the outer form of the preparation. Despite the fact that in the second trimester of the basic processes of organogenesis (formation of internal organs) completed and drugs can not cause serious harm, taking Acyclovir in the 2nd trimester of tablets still not recommended.
How to use acyclovir during pregnancy
This drug is available in several forms: tablets, capsules and as an ointment. The first two forms are not suitable for use by pregnant women because of the high risk of side effects and possible negative effects on the growing fetus.
Acyclovir ointment is available in several concentrations: 2.5%, 3% and 5%. 2.5% ointment is better suited for pregnant womenSince it contains a minimal amount of active agent. When using it in a trace amount of blood absorbed active compound that have virtually eliminates the possible systemic effects.
Acyclovir ointment for use in the 2nd trimester small amount of ointment applied to the eruption area, and gently rubbed. If necessary, apply a large amount of ointment with extensive lesions of a glove.
Side effects
It is extremely rare in the ointment Acyclovir an allergic reaction manifested by itching skin and skin redness. Usually all passes immediately after cancellation ointments and additional treatment is required.
Acyclovir tablets from other possible side effects:
- nausea and vomiting;
- flatulence;
- hypersomnia;
- dizziness.
It also makes the undesirable use of the tablet form during pregnancy.
Acyclovir and pregnancy
Recently, there is increasing evidence of the relative safety of Acyclovir during pregnancy. But we should not unconditionally trust these data: until this information to use acyclovir during pregnancy is best limited in the official statement.
In any case, the decision to use Acyclovir pregnant woman should consult a doctor. Only a specialist with medical education is able to fully weigh the risk to the child of the drug and to determine whether it exceeds the benefit for the mother.
sources:
Vidal: https://www.vidal.ru/drugs/aciclovir__4107
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 1c2f1271-35fa-497d-b17d-07060cf7e6d7 & t =
Found a bug? Select it and press Ctrl + Enter
