Movalis (meloxicam) and Ketorol (ketorolac) belong to the group of nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs are hormonal agents that have a powerful anti-inflammatory effects. Let's try to figure out what is best Movalis or Ketorol, and in what situations they should be used.
pharmacological properties
Once in the body, Movalis prevents the synthesis of prostaglandins (mediators of the inflammatory process) that reduces inflammation. Also, the drug is an analgesic and antipyretic.
The main difference from other NSAIDs Movalis - selective inhibitory effects against inducible cyclooxygenase (COX -2) and minimal effect on COX-1.Imenno this quality drug significantly reduces the possibility of adverse events by ZhKTi urinary system.
Movalis (in therapeutic dosage) has no effect on platelet aggregation and bleeding time does not increase.
Ketorol also relates to non-selective NSAID and possesses impact against cyclooxygenase. The preparation exhibits anti-inflammatory, antipyretic and analgesic properties.
If we compare Ketorol Movalis and it turns out that Movalis will be selective, most in the area of inflammation, rather than on the mucous membranes of the stomach and urinary organs. Whereas Ketorol affects the synthesis of COX-2 and COX-1 alike, which may provoke adverse effects from the gastrointestinal tract and kidneys.
When administered funds
Movalis apply in the following situations:
- degenerative joint diseases, including those for the treatment of pain;
- rheumatoid arthritis;
- ankylosing spondylitis with type;
- in inflammatory processes with localization in the musculoskeletal system, accompanied by painful symptoms.
Ketorol used for symptomatic therapy:
- trauma, sprains and strains;
- toothache;
- muscle and joint pain;
- neuralgia and sciatica;
- rheumatic diseases such as.
Features of the application
Use Ketorol simultaneously movalis not recommended. Combined therapy of two NSAIDs may cause an overdose and cause serious side effects.
When severe pain doctor may prescribe injections or ketorol Movalis. The analgesic effects of the drug is achieved within 30 - 60 minutes.
The duration of NSAID therapy, is appointed the doctor individually, depending on the disease. However, it should be understood that these funds are well relieve symptoms of the disease but can not cure the cause.
If necessary, both drugs can replace analogues, such as diclofenac and meloxicam.
conclusion
Despite the fact that Movalis Ketorol and belong to the same group of medicines (NSAIDs), they are based on different active ingredients which are the main cause of differences between drugs.
The difference between ketorol and movalis due primarily to the influence of meloxicam selective for cyclooxygenase. He actively blocks the synthesis of COX-2. That is why it affects the area of inflammation, whereas ketorolac same effect on COX-1 and COX-2. Ketorol most often used to relieve severe pain and Movalis has a strong anti-inflammatory effect.
Using Movalis significantly less likely to cause adverse reactions from the gastrointestinal tract and urinary tract than the ketorol. However, be aware that the effects of the drugs are directly dependent on the dosage. With increasing doses of the drug increases the risk of developing symptoms of side effects.
sources:
Vidal: https://www.vidal.ru/drugs/movalis__30263
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 70ebe74b-824b-4ee1-a07e-c59492fc925e & t =
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