Stomatitis - a disease of the oral mucosa that can be caused by different pathogens. Accompanied by the appearance of ulcers, fever, weakness. It happens as a separate disease, and a consequence of other pathologies, such as tonsillitis. Acyclovir with stomatitis is prescribed in case of herpetic nature of the disease.
Action Acyclovir with herpetic stomatitis
Acyclovir is an effective antiviral agent. It is active against herpes simplex virus, and Epstein-Barr virus and cytomegalovirus. On pathogenic cells it acts selectively, disrupting the synthesis of DNA, and thus suppressing the reproduction of the pathogen. The advantage of the drug is that it does not affect the genetic material of human cells, so low toxicity.
Acyclovir is particularly effective in acute herpetic stomatitis. The tablets have a systemic effect, penetrating in the lesion of the intestine to the bloodstream. Local application of ointment accelerates healing bubbles or drying out them, reduces itching, pain and burning sensation.
Bonafton, Helepinovaya ointment - and other drugs may be used for the treatment of stomatitis. Acyclovir is considered somewhat outdated, but during the primary episode of the disease shows high efficiency. Approximately half of patients are resistant to this drug, - for them to get rid of stomatitis should choose other means.
Instructions for use
Acyclovir for the treatment of stomatitis can be used in various forms - ointment, tablet, intravenous infusion. In the mild form of the disease is enough local treatment and receiving immunostimulatory and bracing means. In severe requires a combination of external and internal treatment. When stomatitis in adults taking Acyclovir should be a little different than in children, but the difference lies in the dosage.
Ointment (cream)
Guide prohibits drug applied to the mucous membranes of the mouth. Ointment contains components that must not get inside, it is especially dangerous for children. In addition, it can lead to severe inflammation.
Acyclovir ointment for the treatment of thrush is used for application to the lips, so as not to allow the virus to go beyond the mouth and spread on the skin.
How to use the tool correctly:
- Treat antiseptic mouth (3% hydrogen peroxide, Metrogil dental gel, or a solution of chlorhexidine Frc);
- Gently with a sterile bandage or cloth to remove ulcer crusts;
- Dot thin layer of a cotton swab or special spatula applied ointment, capturing and ulcers, and border around them;
- The frequency of application - 5 times a day, a course of treatment - no more than 10 days.
It is important to start treatment can be used to in stomatitis virus did not manage to go on extensive areas of the skin. When joining a bacterial infection further prescribe antibiotics and antimicrobials and anti-inflammatory external means (Vinylinum balm, ointment or Levomekol al.).
Pills
Adults take Acyclovir from stomatitis in tablet form need to 5 times a day 200 mg. Duration of reception - 5-10 days. In severe cases, the doctor may increase the dose to 400 mg. Tablets can drink, and for the prevention of recurrence of herpetic stomatitis (dosage 200 mg 4 times a day).
Attention! Excess prophylactic daily dose of 800 mg in some patients may provoke a sharp aggravation of herpes.
If the patient is obese, the amount of funds calculated in accordance with normal body weight, not actual. Rigorous approach to the choice of the treatment of stomatitis acyclovir schemes require people with kidney failure. For them, the dosage necessary is reduced depending on the degree of impairment of renal function.
When stomatitis in children Acyclovir is assigned as follows:
- after the age of two years, similar to adults;
- child from 3 months. up to 2 years single dose reduced to 100 mg;
- Neonatal shown intravenous agent twice a day with an eight-hour interval between treatments.
The exact dosage and frequency of administration determined by the physician. Read more about the treatment of stomatitis in children using Acyclovir, read this article.
Prolonged or frequent use of Acyclovir reduces the sensitivity of the herpes virus to the drug, so patients with recurrent stomatitis effectiveness of treatment from time to time may be reduced.
A solution for intravenous infusion
This form of medicine is indicated in severe lesions of herpes virus, stomatitis when spread from the mouth to extensive areas of skin and body. Acyclovir is administered in such cases through a dropper for an hour 2-3 times a day. Course duration - 5-7 days.
Contraindications
Acyclovir should not be used when:
- pregnancy (unless the benefits does not exceed the potential risks);
- lactation;
- severe hepatic or renal dysfunction;
- individual intolerance;
- diseases of the blood system;
- in old age.
It requires particular caution Acyclovir use in renal disease. Due to poor elimination from the body, they may be formed of crystals precipitate acyclovir, and this leads to acute renal failure. These patients should be regularly pass urine and blood samples, monitor renal function and dosage for them is chosen smaller. Mandatory control creatinine and urea nitrogen.
Side effects
Most patients means well tolerated. The most common side effects of Acyclovir presented:
- headache;
- nausea;
- vomiting;
- allergic symptoms (rash, swelling of the skin and mucous membranes);
- weakness;
- diarrhea;
- increased production of liver enzymes.
Much less side effects occur such as jitters, dry skin, anemia, drowsiness, convulsions, local inflammatory reactions, kidney failure, confusion. In elderly people the excess concentration Acyclovir with high probability may cause severe adverse reactions in the nervous system.
Important Notes and Recommendations
Acyclovir treat stomatitis must be in compliance with several rules:
- not exceed ten therapy;
- before applying the creams (ointments), skin treating antiseptic;
- during treatment stomatitis drink more water (at least 2 liters per day);
- abandon the sharp, fatty and acidic foods;
- stomatitis start treatment as early as possible - this drug's effectiveness depends largely;
- Acyclovir ointment is not applied to the mucous membranes, and for lubrication of the skin to cover all herpes affected areas.
All people who have ever been in my life herpetic stomatitis, it is recommended to have in your home medicine cabinet Acyclovir. This is due to the fact that the disease often recurs, which is enough to hypothermia, stress, weakened immunity. Reduce the likelihood of acute stomatitis helps a healthy lifestyle, avoiding harmful habits, a balanced diet and careful oral hygiene.
sources:
Vidal: https://www.vidal.ru/drugs/aciclovir__4107
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 1c2f1271-35fa-497d-b17d-07060cf7e6d7 & t =
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