During pregnancy and subsequent breastfeeding, accompanied by enormous changes in the body of the future mother. See if you can take loratadine during pregnancy, and how it does not harm the unborn baby's health.
Changes in the immune system are manifested in the form of increased sensitivity to allergens - even those products and medications that are taken before pregnancy, may cause allergic reaction.
Allergy treatment is complicated by the fact that many drugs are contraindicated in pregnant and lactating women.
Information about loratadine
The drug belongs to the category of antihistamines 2nd generation. In pharmacies sold under the trade names Claritin, Lorageksal, Klaridol, Klarisens, loratadine.
Indications for use are:
- Food and drug reactions;
- Allergic rhinitis;
- Contact dermatitis;
- Hives;
- Allergic conjunctivitis;
- Angioedema;
- Eczema and other types of dermatoses;
- Bronchial asthma;
- Unreasonable allergy symptoms during pregnancy.
Contraindication for use are:
- Children younger than 2 years old;
- Idiosyncrasy.
After receiving tablets absorbed into the blood for 30 minutes and has therapeutic effects:
- Selectively blocking H1histamine receptors, responsible for the development of allergies;
- It inhibits the action of histamine on blood vessels and cells;
- It prevents further development of an allergic reaction;
- Reduces redness and swelling;
- Eliminates itching;
- Dilates the bronchi.
Effect of the drug is maintained for 24 hours. The advantage of loratadine, compared with the early anti-allergic agents (Tavegil, Diazolin, diphenhydramine, Suprastin) - the lack of sleepiness and the use during pregnancy and lactation.
Loratadine has other advantages:
- It does not affect the physical activity and concentration;
- Absorption of the drug is not associated with food intake, therefore, be permitted to take loratadine at any time;
- It has no effect on the central nervous system;
- Rapid onset of effect - after 1-3 hours, depending on the manufacturer and auxiliary substances used in the manufacture of tablets;
- Permission is granted to long-term treatment (up to 1 year);
- Not addictive;
- Affordable price;
- Allowed to drink together with the drugs used during pregnancy (Djufaston, Utrozhestan, iron preparations and other vitamins).
Note! Assign loratadine for prolonged therapy (over 10 tablets) can only physician.
Pregnancy
During pregnancy, you need to take Loratadine with caution, short courses aimed at the elimination of allergy symptoms:
- Pruritus and rash;
- Redness and swelling of the face;
- sneezing;
- watery eyes;
- Rhinorrhea (nasal discharge flow).
Studies that would confirm the harmlessness of loratadine during pregnancy is not carried out for humanitarian reasons and the high cost of such research - billions of dollars.
However, FDA (Management of quality control of medicines and foods) investigated the teratogenic effect exerted by the drug in animals. During safety testing has been revealed for the embryonic development of the child. Considering the possible risks, to decide the question whether pregnant loratadine, should the doctor.
Apply loratadine during pregnancy in 1 trimester is not recommended - at the time the child is formed by the body, there is a visceral tab. Use of the drug can impair development and cause birth defects.
In the 2nd trimester of pregnancy to take Loratadine is permitted in extreme cases, to eliminate the symptoms of allergy, strictly on the evidence, following dosing regimen specified in the instructions for use.
In the third trimester of antihistamines are shown in case of emergency.
Application breastfeeding
Application lactation permitted provided that during the reception of loratadine, breast-feeding is suspended.
After a course of treatment, the child again is transferred to breast feeding.
Dosing during pregnancy and lactation
In pregnancy, the tablets containing 10 mg of active substance. 1 tablet taken once a day, regardless of the meal with water. In the presence of severe liver disease, the dose reduced - drink 1 tablet every other day or 1/2 tablet daily. Duration determined by the severity and the severity of the allergic reaction. Minimum recommended course - 3 days, in mild cases, limited to a single application.
sources:
Vidal: https://www.vidal.ru/drugs/loratadine__3595
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 86d9d5c6-cd64-49e4-8081-c35aa2f78371 & t =
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