When chronic inflammatory diseases of the skin preparation is the choice of a large range of products. Doctor will choose what is best: Levomekol or Chloramphenicol, on the basis of clinical pathology.
Compositions and forms
Levomekol released in the form of a white uniform ointment containing 7.5 gram per mg of chloramphenicol and 40 mg methyluracil. The shaping composition contains the polyethylene glycols of different molar mass.
As part of Chloramphenicol ointment - 1 gram of the same active ingredient per one hundred grams. Massing ingredients: Macrogol, purified water, mineral oil, propylene glycol.
medicinal properties
Compare Chloramphenicol with levomekol possible by their effect on the body. Levomekol comprises chloramphenicol with pronounced antimicrobial action. The mechanism of effect on pathogenic microflora is to tackle the peptide synthesis in bacteria, in particular coccal infections and E. coli.
Methyluracil has a marked healing and granulation effect, accelerates tissue scarring process and reduces inflammation.
Polyethylene glycols composed of the formative components capable of adsorbing necrotic mass and potentiate the therapeutic effect of the active substances.
Chloramphenicol also has a similar antibacterial effect, as the active ingredient is identical, only supplemented in levomekol methyluracil. The difference between levomitsetina levomekol and lies in the concentration of chloramphenicol - chloramphenicol - 10 and 7.5 mg, respectively.
Indications for
Levomekol prescribed for such diseases:
- purulent lesions of the skin to infection;
- non-healing trophic ulcers type;
- burns with infection;
- internal acne.
In addition to the indications given in the annotations to the drug, Levomekol actively used for hemorrhoids, otitis and other inflammatory diseases.
Chloramphenicol is an antibiotic used to treat wounds and burns in the granulation step and removing necrotic masses. In dermatology, the drug is effective against acne, eczema, purulent inflammations.
Features of the application
Levomekol not apply for more than five days. On the fifth day it is recommended assignment of funds to repair damaged skin. Chloramphenicol combine with miramistinom, chlorhexidine or the like, if necessary washing solutions purulent exudate.
Application levomekol for a long time or over large areas of the skin can cause skin sensitization hereinafter with antibiotics. As a part of the same antibiotic chloramphenicol, its application is also limited in duration.
Side effects
Levomekol can provoke skin sensilibilizatsiyu long-term treatment.
Possible side effects:
- swelling;
- hives;
- rash;
- itching.
These symptoms are an indication to remove the drug.
Chloramphenicol as one of levomekol components separately when applied topically did not induce apparent side reactions other than allergy.
joint application
Levomekol applied simultaneously with chloramphenicol inappropriate. In the case of inflammatory disorders and integrity of the skin, Levomekol will be more effective, since it contains more methyluracil and glycols.
Chloramphenicol well as analogue, will only antibacterial effect. Since it is already a part of levomekol together to apply the ointment is not necessary - increased efficiency is not observed.
sources:
Vidal: https://www.vidal.ru/drugs/levomecol__1655
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = cf36eacd-b2d6-4389-92b4-4fb0e257825f & t =
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