Effects of the drug on the body
Hydrochloric acid is produced in parietal (parietal) cells of the stomach. In some diseases, the excess acidity causes damage to the gastric mucosa, intestine and esophagus, causing inflammation and injury (ulcer formation). Diseases such etiology accompanied by pain, heartburn, a chair violations. Diagnosed gastric secretion is an indication for PPI - proton pump inhibitors, which include omeprazole.
Positive effect
Omeprazole entering the stomach, activated tubules outputting these cells at the molecular level and blocks the final step of acid production. Regular intake of medication can achieve sustained reduction in gastric acidity and to get rid of many unpleasant symptoms. Effect of the drug begins during the first hour after administration and continuing up to 24 hours.
Due to the property to reduce the acidity of gastric secretion, omeprazole helps:
- safely arrest the sharp pains in the stomach and other parts of the gastrointestinal tract;
- get rid of heartburn episodes;
- in the complex therapy - to accelerate the healing of lesions on mucous membranes and reduce inflammation;
- reduce digestive discomfort, to stop the feeling of nausea, stop the attacks of acid regurgitation.
Therefore, the drug is prescribed for a variety of pathologies - he used in the treatment of gastrointestinal ulcer disease, gastritis with high acidity, with reflux esophagitis and other diseases. According to the instructions, the recommended duration of treatment course is up to 8 weeks. In many patients, the question arises whether omeprazole is harmful if it is a long time to drink? The answer is known and confirmed by research.
the negative impact
In various diseases PPIs (proton pump inhibitor) is assigned to the course of 2 to 8 weeksAt the discretion of the attending physician. Exceeding the recommended duration of administration is dangerous to health.
Omeprazole - is a potent drug, its use is contraindicated and can cause side effects. The likelihood of complications increases with prolonged administration.
What is the harm of omeprazole? Consider the details:
- The acid in the stomach, along with digestive enzymes responsible for the digestion of food quality. Reduced secretion of gastric acidity leads to poor absorption of nutrients. Therefore, chronic administration of drugs blocking the secretion of hydrochloric acid develops anemia and vitamin deficiencies. High probability of various diseases caused by a lack of essential vitamins and minerals;
- Long-term suppression of gastric acid stimulates the development of various infectious diseases such as within the lumen of the gastrointestinal tract, and beyond;
- If you long to take omeprazole in the body's cells accumulate protein compounds. This impairs the functioning processes and accelerate cell aging;
- Exceeding the recommended course of treatment with a negative effect on the kidneys and liver, brain and worsens cardiac activity. Constant reception of the drug, especially in the elderly, may trigger the development of dementia and heart attacks.
Thus, all the negative effects of prolonged use of omeprazole are due to two main reasons:
- Deterioration assimilation vital substances from food (iron, calcium, magnesium, vitamins, and others);
- Accumulation of toxic compounds in the body cells and deterioration of their function.
It is important to stick to the designated physician treatment regimen - this will minimize possible complications. Decide how long you can drink without interruption omeprazole, should a doctor, based on the individual clinical picture.
Damage continuous dosing
Many patients experienced the positive effect of the formulations of omeprazole, may not refuse to use them. Medications that reduce gastric acidity, becomes for them a daily necessity. This is a very dangerous trend. Studies have shown that if the time, more than a year, to take omeprazole, are more likely to develop the disease as follows:
- gynecomastia;
- myopathy;
- Renal and hepatic failure;
- Anemia (iron deficiency);
- Osteoporosis (calcium loss from the bones);
- Oncological diseases;
- Polyposis of the stomach;
- neuropathy;
- Swelling.
Reviews of people for a long time to take the drug on the basis of omeprazole (Omez, Ortanol and others), confirm this information.
How to avoid complications
To prevent the development of these diseases, it is first necessary to adhere to assigned physician treatment (including diet, mode and take all medication as prescribed according to scheme). If at the end of the course the symptoms remain, that is no reason to continue unchecked omeprazole. It is necessary to consult a doctor and undergo additional tests. Perhaps pathology was incorrectly diagnosed and treated it is necessary with the help of other drugs.
In addition, if a doctor recommended a long time to take omeprazole, it is advisable to supplement the course multivitamins, calcium and iron, to make up the required receipt of these substances body.
Reduce the negative effects of long-term therapy with PPIs help breaks between courses, a duration of at least 2-3 weeks (the body can derive accumulated during treatment substances). If necessary, these periods can drink antacids (Almagel, Maalox) to protect the gastric mucosa from the effects of aggressive acid.
It is very dangerous for a long time without a break to take omeprazole, it is fraught with the development of serious pathologies. The most reasonable alternative to long-term use of this tool is a thorough examination of the body and comply with all recommendations of the physician. If you adhere strictly to the assigned diet in a timely manner and according to the scheme to take all prescribed drugs, observe preventive measures - it is possible to achieve stable remission or complete cure diseases GIT. In this case, the need for omeprazole will disappear by itself.
sources:
Vidal: https://www.vidal.ru/drugs/omeprazol__3120
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 83097c54-4fcd-4122-b96d-1b90b38d8823 & t =
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