TTG analysis. What is it, the rate of hormone in men, women, pregnancy age, the table. That shows means, decoding. Prepare how to donate

The analysis on hormones - this is an important medical procedure that should take place every person at least once a year. Hormones - this active substances that have strong biological effects on the body and develop organs, tissues and individual cells. One of the most important indicators - a TSH, oxytocin, adrenaline, testosterone.

A total of more than 150 species are distinguished, each of which is responsible for one or several important physiological functions. The only way to diagnose a person has insufficient or excessive concentrations of hormones - is the delivery of blood to the laboratory for analysis. One of the most important hormones in need of systematic verification, - thyroid-stimulating (TSH) produced by the pituitary gland.

TSH role in women and men

Pituitary - a gland, called brain appendage, it has a rounded shape and is located around the brain (on the bottom).

Location of the pituitary is closely connects it with the hypothalamus - an important brain department, which ensures the production of important hormones for human life:

• oxytocin;
• vasopressin;
• of growth;
• lyuteotropnogo;
• thyroid stimulating;
• melanocyte.

They are secreted into the bloodstream and affect the flow of all vital processes of the body, since the regulation of sugar levels, ending the normalization of heart rate. The hormones are synthesized in the glands without external ducts (pituitary, thyroid, thymus) related to the body's endocrine system.

TTG synthesized by the pituitary gland to affect the body through the stimulation of thyroid hormones T3 and T4.

T3 - the most active thyroid hormone, containing a 3 atoms of iodine and performs the following functions:

• Ensuring the growth and development of the organism.
• Thermoregulation.
• Rise in blood glucose.
• Catabolic and anabolic effects (depending on concentration).
• Stimulation of positive nitrogen balance.

Effect of thyroid

T4 - the most common among thyroid hormones (90%). It can also be found in the free form and as a complex with proteins. The main function - catalytic. Due to the action of the hormone, the process of energy production in the cleavage of complex substances faster.

Increase of heart rate, weight reduction and increased irritability occurs due to the action of T4 on the body. Thus, TSH, regulating the production of only 2 hormones affect a huge spectrum of processes of the human body.

By increasing or decreasing the concentration of T3 and T4 pituitary begins to productively produce TTG and vice versa - to increase with increasing TSH concentration T3 and T4. This process is called negative feedback.

menstrual regulation

Women are particularly susceptible to surges of TSH due to its influence on the course of the menstrual cycle. Triiodothyronine (T3) and thyroxine (T4) affect protein synthesis, which is required for binding of sex hormones. Lack T3 iT4 sooner or later lead to excessive synthesis tireoliberina hormone.

This can cause an irregular cycle, or lack thereof. Excess hormones also have a negative impact on a woman's body - possibly a violation of oocyte maturation, which will trigger a chain of negative consequences.

Formation of secondary sexual organs

Unrelated male sex hormones, testosterone and androsterone, lose their activity, and can not stimulate the growth and shape of secondary sexual characteristics in the right measure. The lag in the sexual development of the child, and later manifestation of secondary sexual characteristics - a consequence of a lack of thyroid-stimulating hormone.

In adolescence (teenage) age of the body is particularly sensitive to changes in the concentration of hormones including TSH. Boys and girls with impaired thyroid function because of an excess or deficiency of thyroid stimulating hormone have to puberty problems and need systematic observation in Endocrinologist.

TSH norm in men and women over the age of

Analysis TTG - it is a means for determining the general state of the endocrine system, necessary for any lifestyle. Norma is constantly changing depending on the age.

The following indicators are normal for women:

Age	TTG norm in mU / l
The first month of life	1.1-17
1-3 months.	0.6-10
3 months to 1 year	0.4-7
1-5 years	0.4-6
5-15 years	0.4-5
15-49	0.4-4
Over 50 years	0.27-4.2

With increasing age gradually decreased hormone level, however, the older people, the lower the concentration and less required rate. In menopause reduced number of follicles in the ovaries, thyroid gland becomes smaller, and the pituitary gland begins to produce a smaller amount of thyroid-stimulating hormone - a normal physiological phenomenon.

It should be noted that even during the day the concentration varies, up to a maximum value during the night hours. This variation is related to the biological rhythms of the human body - the peaks hormone (testosterone, melatonin, etc.) account for different hours. Hence the need to ensure uniform time delivery of analyzes - morning time.

The rate for men:

Age	TTG norm in mU / l
The first month of life	1-40
1-3 months.	1.7-9.2
3 months. - 5 years	0.5-10.1
5-15 years	0.3-6.1
15-18 years	0.3-5.1
18-54 of	0.3-4.1
Over 55 years	0.4-9

Men are not so often found abnormalities in the development of TSH. This is due to the rarity of the pathology of the thyroid gland in the male sex. hormone levels in males and steadily decreases with age and reaches a minimum value after 55 years.

Table TSH standards for gestational age

Placental hormone hCG, secreted into the bloodstream expectant mother affects all the organs and glands of the body, including the thyroid. Through feedback between this gland hormones, T3 and T4 concentration abruptly rises, causing a decrease thyroid stimulating hormone.

Changing the concentration of TSH is associated with physiological changes in a woman's body - hormonal changes, the qualitative composition of the body, the processes of anabolism and catabolism rate. Changing lifestyles also affect the hormonal background, in particular the hormone TSH.

In the first trimester fetus can not independently produce thyroid hormones. This is due to the insufficient development of the body, the foundation of which is laid on the 16-17 days of fetal development. The source of the hormone becomes the parent organism, which is forced to secrete increasing amount of TSH.

This is a natural process to ensure the fetus with the necessary resources in the form of hormones. In the second trimester the embryo starts functioning pancreas, providing its own secretion. The woman in this period again begins to hormonal changes - decreased triiodothyronine, thyroxine and increased TSH hormone.

In the third trimester of thyroid hormones figures come to normal.

Table of standard values:

Trimester	TSH concentration in mIU / l
1	0,1-0,4
2	0,3-2,8
3	0,4-3,5

Indications for TSH assay

The doctor prescribes analyzing the change in the TSH at suspected one of the pathologies of the thyroid gland or the following health problems:

• constipation;
• dryness, or swelling of the skin;
• violation of the menstruation;
• arrhythmia;
• hypothyroidism;
• overweight;
• chronic fatigue, lethargy;
• sudden loss of hair;
• disorders of the pituitary gland;
• goiter;
• tremor;
• alopecia;
• myopathy;
• infertility;
• sleep disturbance;

Analysis on TTG necessarily given to women who have reached menopause, pregnant women, people who are genetically prone to thyroid disease. Such patients require special monitoring hormonal levels. This procedure will help to identify predisposition to disease or occurrence them in the early stages.

People are ever subjected to hormonal treatment, and forced to timely monitor changes in blood hormone concentrations to assess the quality of therapeutic effects.

With the passage of thyreostatic, suppressive therapy or replacement values ​​of TSH is needed to monitor the effectiveness of the procedure. People who previously have problems with the functioning of the endocrine system, the analysis should take at least 2 times a year.

Preparation for the study. When the blood sample is taken?

Analysis TTG - it is a study that reflects the quality of the functioning of the hypothalamic-pituitary axis and the thyroid gland. to prepare for the delivery of hormone TSH is necessary to obtain high quality results in advance.

1. During the month should stop taking hormonal methods (as directed by the endocrinologist).
2. 3 days before the date you want to exclude iodine-containing drugs, alcohol, smoking.
3. Any physical and emotional load will affect the results of the study, so the day before the date it is necessary to lead a regular life as much as possible and do not expose the body to stress.
4. Blood donation is carried out on an empty stomach in the morning (8-12 hours without food). Drinking water is allowed.
5. Immediately prior to the delivery need to remain calm and not to carry out the procedure in an excited state. It is best to sit quietly in a chair for 10-20 minutes.

It should be noted that the female menstrual cycle has no effect on the concentration of TSH hormone, so Both men and women can get tested at any day, to first prepare procedure. TSH concentration depends on the time of day, reaching a minimum value in 17-19 hours and maximum at night.

Morning time provides a common average value. laboratory conditions must be sterile. All gloves and needles are used once. Blood sampling is carried out from a vein in the patient being in a state of rest. Hand fixed palm upwards, the elbow joint maximum unbend. On the hand region disposed above the elbow stretched rubber band.

Fist squeezing, the patient pumps blood into the cubital vein after the tourniquet is tightened, and a nurse performs the process of intake of biological material. After the procedure, should bend the arm at the elbow for 5 minutes. to prevent bruising at the puncture site. The resulting material was placed in a test tube and to give a chemiluminescent analysis.

When the results are ready?

Modern techniques allow you to quickly obtain accurate results - the deadline for receipt varies from one to four working days. Getting results are more dependent on the efficiency of the laboratory than the duration of the investigation procedure. On the analysis does not go more than a day, and in the case of urgent research enough 2-3 hours.

deciphering responses

Normal values ​​depend on the gender, age and quality of the equipment. It is important in conducting multiple studies to address in a clinic in order to reduce errors in the results that have arisen as a result of differences in technical equipment.

Various diagnostic methods may cause a discrepancy values. In any case, when the normal discrepancy indices hormone concentration is not included in the corridor of acceptable values ​​and can be raised or lowered.

Symptoms and causes of elevated TSH

Analysis TTG - it is an important study helps to identify the presence of abnormalities. Overestimates the concentration of hormone is called hypothyroidism.

It can indicate the following deviations:

• Deficiency of vitamin D.
• Iron-deficiency anemia.
• The excess iodine in the body.
• Diseases of the adrenal gland.
• Benign or malignant tumors of the pituitary.
• Thyroiditis.

Only an endocrinologist can clearly assess the state of health and diagnosis.

Elevated hormone may be due to the medication or problems with other organ systems. Diagnosis and treatment of hypothyroidism in the early stages helps to reduce the risk of diabetes, atherosclerosis, hypertension and other diseases, significantly worsens the quality of life.

Symptoms and causes of decreased TSH

Depending on the reasons for the surrender of TSH and existing pathological manifestations endocrinologist can put one of the following diagnoses:

• Development of hyperthyroidism - the lack of thyroid-stimulating hormone.
• Diffuse toxic goiter - an enlarged thyroid gland, accompanied by a breach of its functioning.
• Adenoma.
• Cachexia - depletion of the body, including weight loss and disruption of mental processes.
• Malignant or benign tumor of the thyroid gland.

The doctor - endocrinologist rarely can diagnose only one TTG analysis. Hormonal body includes a large variety of hormones influencing each other, so to ascertain the cause of competent needed accompanying analyzes T3 and T4.

Disease of the pituitary or hypothalamus can influence not only the level of triiodothyronine and thyroxine, but also on the functioning of the thyroid gland. If it affects the pituitary occurs secondary hypothyroidism, accompanied by a decrease in TSH and a lack of thyroid pathologies.

Causes of secondary hypothyroidism are as follows:

• Infection.
• Injuries of the skull.
• Surgical procedures.
• Tumors and tumors of the pituitary and hypothalamus.

In people with decreased TSH level is usually the following symptoms: emotional stress, tachycardia, dry skin, trouble sleeping. For non-core may include soreness in the wrists, numbness and tremor.

In men, there are less problems with the endocrine system, so the lower the TSH is not common and is usually indicative of impotence, low testosterone levels, osteoporosis and infertility. Timely diagnosis, prevention and treatment can fully restore the endocrine system and get rid of any complications.

General principles of normalization of TSH levels

Analysis TTG - it is research that can inform about the time of undesirable diseases and pathologies. Therefore, when problems are detected with the concentration of TSH different treatments are assigned depending on the diagnosis. The main way - a hormone replacement therapy.

Its main objective is to replace the lost capacity pharmacological thyroid - synthesize hormones in the right quantity. Synthetic drugs make up the missing hormones - TSH, T3, T4 and restore normal hormonal balance.

What is the cost analysis in clinics of Moscow, St. Petersburg, regions?

Minimum analysis delivery cost is 500 rubles. in Moscow and St. Petersburg. Price in the region ranges from 400 to 1000 rubles. depending on the urgency of the order, the clinic and the town. The difference in prices between the Moscow and Leningrad regions is not much different from other regions. Numerous laboratories operating throughout Russia have a single price for different cities.

A significant difference in price will occur in private clinics and hospitals.

Complex hormonal assays include spectrum thyroid hormones and pituitary, starting from 3 thousand. rub. and reach 15 thousand. depending on the amount of hormones in the study. Especially popular are the complex analyzes for couples planning pregnancy and women aged 45-55 years, members of the menopause.

The cost of such research in the laboratories of the popular Moscow region starts from 5 thousand. rub. The higher price is justified by a comprehensive approach and a lot of information data. Endocrinologist can more fundamental approach to treatment.

Analysis of TSH to a hormone - it is a very important indicator of the quality of the work not only of the endocrine system, but also the whole organism. This hormone affects the functioning of all systems.

The excess or deficiency can cause serious irreparable changes entailing dire consequences such as infertility or diabetes. Timely diagnosis will not only make a healthy baby, but also competently enter into menopause or just to protect themselves from possible consequences.

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