Clomid. Instructions for use for women. Reviews, price, analogs

Clomid - a synthetic drug, designed to normalize the functioning of the reproductive system in women. It normalizes the menstrual cycle and stimulates ovulation.

It is also used to improve sperm quality in men. Accepted must be strictly according to the instructions (non-compliance with the dosage can cause hormonal failure) and a gynecologist appointment.

Release form and composition of the drug

Clomid is produced in tablet form, on one side coated logo drug to another risk. The tablets are white to yellow or gray tint, no odor.

The composition 1 tablet contains:

1. Active component - clomiphene citrate (50 mg). It normalizes the production of sex hormones by acting on the hypothalamus and the gonads.
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2. Auxiliary elements.

They are as follows:

• gelatin (2 mg). It is used to impart consistency preparation and strengthens blood vessels, cartilage and bone tissue;
• magnesium salt (2 mg). Is used to combine hard connected elements, it normalizes the functioning of the endocrine system. In large doses, can trigger the development of cancers and necrosis of healthy cells;
• stearic acid (2 mg). Needed to give a stable shape means, and also improves the absorption of the drug components in the gastrointestinal tract;
• talc (5 mg). Used for thickening the preparation has an antibacterial property;
• potato starch (39 mg). Used for thickening elements. Additionally normalizes glucose concentration and intestines;
• lactose monohydrate (100 mg). Normalizes metabolism, improves the absorption of the drug.

Adjuvants enhance the effect of the active element and impart the desired drug form.

The tablets are packed in an amount of 10 units. in paper / aluminum blisters or vial made of dark glass.

pharmacological properties

Klostilbegit (instructions for use for women based on the pharmacodynamics of the drug) by normalizing hormone regulates the ovulation process. Not a hormonal agent.

The active element affects the formation of estrogen in the ovaries. When hormone deficiency oocyte maturation process slows down. Clomiphene increases the production of estrogens, normalizing the ripening process. Elevated levels of the hormone violates the menstrual cycle and prevents normal development of pregnancy. In this case, the active element reduces the production of estrogen.

Decreased or increased production of hormones determined dosage formulation. Therefore it is not recommended to start treatment without examination and without prescription needed dose gynecologist. Pills are not accompanied by the development of secondary sexual characteristics (hair on the face, breast reduction) and does not disturb the functioning of the ovaries.

Tablets, after use, are absorbed into the blood in the digestive tract and metabolized in the liver. The highest activity of the drug observed after 6 hours. Withdrawal of the drug from the feces within 7 days.

Indications

The main purpose of the drug to normalize the process of ovulation.

Clomid is used in the following cases:

• Violation of the development and maturation of the egg, so that it does not leave the ovary.
• The absence of menstruation for more than 6 months in women of childbearing age. It may be due to changes in hormonal levels or taking oral contraceptives.
• Changes in menstrual period spotting between cycles.
• Violation functioning ovaries, accompanied by disruptions in the menstrual cycle.
• Prolactin synthesis increased, accompanied by evolution of milk and colostrum in the absence of pregnancy and lactation period.
• Failure functioning of the reproductive organs.
• A protracted recovery period after birth.
• Short menstrual period (1-2 days) with an interval of 35-40 days.

The drug is also assigned the male gender in the presence of a small amount of sperm semen parameters. The probability of conception increases in 2 times from the first course of therapy.

Contraindications

Clomid (instructions for use for women gynecologist needs to be adjusted to suit the individual characteristics of the organism) forbidden to take in the presence of abnormalities.

For example:

• intolerance or allergic reaction to components of the drug;
• violation of assimilation of lactase;
• bleeding from the uterus, of unknown etiology;
• adrenal failure operation;
• pathological or neoplastic processes in the pituitary gland, affecting the functioning of the body;
• tumor formation on reproductive organs;
• cysts in the ovaries;
• kidney or liver disease in the acute form;
• pathologies of the visual organ;
• thyroid disease in violation of its functioning;
• pregnancy and during breast-feeding;
• endometriosis (a disease characterized by the growth of the inner layer of the uterus endometrium I).

The presence of any item is the reason for the replacement of the drug analog.

Instructions on the use of Clomid for women and dosage

drug therapy (course and dosage) depends on the type of pathology and the patient's general condition. Tablets are taken together with food to 1 day.

pathology View	Features of the application	Dosage	length of treatment	notes
Infertility	With regular menstruation treatment starts on day 5 month	50 mg	5	Requires control of therapy, which is made by delivery of analyzes and hardware survey
When disturbed follicular phase of therapy begins at the third day of the cycle	50 mg	5
In the absence of menstruation treatment is given on any day	50 mg	5	Treatment is carried out before the onset of ovulation. In the absence of effect of the drug dosage is doubled, the course is repeated. If there is no result, you need a break 3 months and repeat the course with 100 mg Clomid. In the absence of effect is chosen a different method of treatment. When treatment is necessary to control the patient's condition. Shall tests and examinations carried out using the apparatus
Absence of menses due to hormonal contraceptives	50 mg	5	In the absence of menstruation after the course of therapy, the treatment is repeated with a dose of 100 mg. When there is no effect after repeat treatment, the patient is carried out inspection and replacement treatment
polycystic ovaries	Initiation of treatment is determined by the gynecologist	50 mg	Gynecologist appointed individually by flowing forms of the disease	—
To recover sperm quality (men)	—	50 mg. Take 2 times per day	6 weeks	After the course they have control over the dynamics of therapy.

Data in the table are corrected gynecologist / urologist with the severity of disease and the body's response to treatment.

Side effects

Application Clomid accompanied by side effects. To reduce the probability of their occurrence is necessary to comply with the instructions, especially the advice of a doctor. Is assigned control of analyzes and surveys hardware celebrated speaker treating disease in women.

Possible adverse effects of therapy:

• Sudden dizziness, and headache.
• Soreness in the stomach after eating. Rarely observed acute abdomen.
• Violation of chair and increased flatulence.
• Unreasoning anxiety, depression and sleep disturbance.
• Quick breakdown. Slowness of movements and psychological response.
• Weight change in the direction of increasing. Due to increased appetite.
• Periodic fever with a rush of blood to the face.
• Decline in the quality of vision (double vision and blurring of objects) and the fear of the world. After completion of therapy, vision is restored.
• Violation of the heart rate.
• Increasing the viscosity of the blood to form clots.
• Chronic administration means there is hair loss.
• Allergic reactions (rash, itching, runny nose).
• Palpitations and increased urination.
• Tenderness in the lower abdomen (symptoms are similar to the onset of menses).
• Swelling and breast tenderness.
• Rarely, but it noted an increase in the size of the ovaries. In this case, the treatment is stopped until the ovaries do not recover. When further decreasing the dosage of the drug therapy.
• Menstruation can proceed with increased morbidity. There may be bleeding in the middle of the cycle.
• Active component increases the viscosity of the mucus in the vagina, resulting in dryness and conception complexity.
• It increases the probability of conceiving multiple embryos once. As well as the development of an ectopic pregnancy.
• In the presence of endometriosis or uterine fibroids, at the initial stage, Clomid accelerates the development of pathology.
• The male sex therapy may be accompanied by pain in the scrotum.
• Nausea, sometimes the presence of vomitus.

Because of the large list of side effects requires strict control treatment, compliance rate and dosage.

Overdose

If you accidentally exceeding the dosage can be observed the following violations of the drug:

• severe headaches, as well as in the area of ​​the pelvis and abdomen;
• abundant vomit;
• an increase in temperature and a strong rush of blood to the face;
• flash before his eyes, and a sharp decline in the quality of vision;
• ovarian enlargement in size;
• increasing the diameter or narrowing of blood vessels.

If poisoning recommended gastrointestinal lavage and activated charcoal method. Data cleansing the body by other means no drug.

special instructions

Clomid (instructions for use for women to be clarified in the treatment) is recommended to take in view of the available individual instructions. They should also discuss the gynecologist when administering the drug.

In the treatment and preparation for therapy is recommended:

1. Undergo a thorough inspection and examination to determine the cause of the pathology, as well as to determine the precise dosage and course of treatment.
2. Exclude the presence of contraindications (especially cystic ovarian endometriosis and bleeding). Otherwise, the treatment can lead to infertility.
   
3. In the presence of the diagnosis of infertility to determine the cause of the pills is allowed after removal of the root causes.
4. With the development of side effects such as an increase in size of the ovaries is recommended to immediately stop receiving funds. If necessary, continue the course of treatment, dosage reduction and adjustment of the duration of therapy (downward) is made by experts.
5. For hormonal balancing, after completion of therapy, prescribers to increase the production of progesterone
6. Producing control over the functioning of the thyroid gland the liver and kidneys.
7. The specialist should regularly monitor the dynamics of treatment (every 2-3 days), if necessary, make timely adjustments.
8. In the absence of dynamics of treatment, made repeated diagnostics causes pathology and adjusted full course of therapy.
9. During treatment can not drive vehicles and do the works that require attention, because of the possibility of deterioration of quality, and to reduce the motor and psychological reactions.
10. In the presence of diabetes necessary to adjust the reception insulin or drugs used for reducing sugar concentration, as part of the lactose increases the amount of glucose in blood.
11. When side effects need to reduce the dosage of the drug or produce replacement (makes attending specialist).
12. Maximum use of tablets, no more than 6 courses (over a lifetime). With more use, the treatment may result in ovarian failure and early onset of menopause. Accordingly, complete infertility women. The only possibility would be to have a baby using IVF with "foreign" egg.

Pills increase the likelihood of multiple births. If you would not birth of several children at the same time you need to choose another method of treatment.

drug interactions

Klostilbegit recommended to take in conjunction with drugs normalizing operation of the internal layer of the uterus to prepare for the carrying of fetus. This increases the likelihood of a quick conception.

Clomid should not be taken concurrently with drugs with similar effects. This enhances the effect of side effects. Also prohibited taking medication to thin the blood, may develop uterine bleeding.

Pills and antibiotics together increases the burden on the liver, this may lead to serious pathologies.

It is not recommended for the treatment of drinking alcohol, it is a bad influence on the functioning of the liver and can harm the development of the fetus, if the pregnancy took place. The combination of the drug with other medicines have not yet been studied.

analogs

Clomid (instructions for use for women contains complete information about the ban, side effects and nuances use) is permitted to replace the analogue, when necessary, only the treating specialist, after repeated survey. List of drugs analog Clomid below.

Clomid:

• produced in tablet form the same active element. Not a hormonal agent. The main purpose of the drug - to stimulate ovulation;
• treatment of this preparation is divided into 3 stages. Originally assigned dose of 50 mg for 5 days with 5 days of the menstrual cycle. Next (step 2 and 3) 100 mg of a similar pattern;
• Tablets are forbidden to receive the presence of bleeding unexplained etiology and pathology of cystic formations kidney and liver. In the treatment may experience ovarian enlargement in size and quality of the violation. Cases of overdose have not been recorded;
• the treatment is recommended to control the size of the ovaries. As well as therapy increases the likelihood of multiple pregnancy;
• interaction with other drugs has not been studied tablets;
• Tablets can be purchased only with a prescription. The average price of 750 rubles drug.

clomiphene:

• available in tablets with the same active element. Not a hormonal drug. Action tablets aimed at normalization of estrogen and stimulate ovulation;
• tablets therapy begins on day 5, 50 mg for 5 days. If no effect dosage is increased by 3 times or renewed therapy to 10 days;
• contraindications and side effects similar to the drug Clomid. In case of overdose may result in poor quality. Produced removal of the drug, vision is restored by yourself;
• the treatment is necessary to make control over the size of the ovary and eye;
• tablets combined in the treatment;
• It means sold with a prescription. The average cost of 600 rubles.

proginova:

• product produced in the form of dragees with an active element of estradiol valerate. A hormonal agent, appointed to fill the lack of estrogen;
• receiving pills similar to use of oral contraceptives. Self-termination of treatment before completion of the course, can lead to uterine bleeding;
• Pills have a big list of contraindications and side effects. Therefore, the drug is not recommended for use without prescription gynecologist. In case of overdose observed the development of uterine bleeding;
• for the prevention of side effects and complications of pills taken under the constant supervision of a gynecologist;
• the drug is not combined in the combined treatment, the period of therapy requires the abolition of all drugs;
• Pills are sold only by prescription. The average price of 400 rubles.

Puregon:

• It means produced in the form of solution with an active element follitropin beta. A hormonal drug. Assigned to the normalization process of ovulation and hormone;
• the medicine is injected subcutaneously. The duration of therapy and the required dosage is selected individually according to the patient's condition and the type of pathology;
• It is contraindicated in the presence of cancers, ovarian cysts and thick blood. Injections can provoke swelling of the injection site of administration, the development of cysts and uterine bleeding. An overdose of the drug were noted;
• treatment injections given after a full examination. The drug is administered by the attending specialist (not allowed at home);
• shots are combined in a complex treatment;
• the solution is sold under a prescription. The minimum price is 6500 rubles.

recommended further read with contraindications and side effects after purpose analog. If one of prohibitions for receiving a means to inform the attending gynecologist. During therapy should be under the supervision of a specialist and produce the necessary examinations.

Terms, conditions of sale and storage

Tablets should be stored out of the reach and dark place, in a complete package or a tightly closed bottle. Temperature range from +15 to +25 degrees. Subject to the conditions a shelf life of 5 years. Can be purchased at the pharmacy with a prescription specifying for receiving medication instructions.

The price of Clomid in the drugstores of Moscow, St. Petersburg, regions

The price for Clomid has differences depending on the region. Packaging form (blister or bottle) at a price not significantly affected.

City	The minimum price in rubles	The maximum price, rbl.
Moscow	480	540
St. Petersburg	520	570
Khabarovsk	580	620
Permian	490	590
Yekaterinburg	500	540
Sochi	550	620
Volgograd	520	580

Clomid is recommended to buy in a pharmacy proven, low price often means a forgery. At the use of tablets according to the instructions and with all the desired pregnancy advice for women, it can occur immediately after treatment. In the presence of side effects of the application means is stopped.

Author: Svetlana Kotlyachkova

Registration of the article: Lozinski Oleg

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