Fluoxetine. Reviews of patients taking the drug, instruction, recipe for weight loss

One common antidepressants are responsible for the reuptake of serotonin and belong to the group of selective inhibitors considered fluoxetine. The drug is registered researchers from Eli Lilly and Company in 1974. Since then, from the patients you can hear many different comments, most of them positive.

For what is used a means of

The drug is prescribed by a doctor for such disorders patients:

• signs of alcoholism;
• depression with accompanying fear and obsessions;
• bulimia nervosa;
• obsessive-compulsive disorders;
• anorexia;
• schizophrenia;
• schizoaffective psychosis;
• bipolar disorder;
• metabolic disorder due to the use of diet.

The above diseases are manifested in various forms: mild, moderate and severe. Doctors noted data about the successful appointment of patients antidepressant for chronic headaches.

These diseases are accompanied by the following symptoms:

• poor appetite;
• nervousness;
• non-perception of events in the environment;
• distrust;
• fear;
• obsessions;
• psycho-emotional state;
• phobias.

Fluoxetine is often prescribed to patients in a depressed state, the organism which does not take other antidepressants. In cases of mental disorders specialists prescribe a drug in combination with other medicines.

The composition of Fluoxetine

For the manufacture of an antidepressant addition to the active component, the hydrochloride, the following elements are auxiliary steps:

• lactose monohydrate;
• starch powder;
• ctearinovaya acid;
• colloidal silicon dioxide.

To create manufacturers use framing shell:

• gelatinous mass;
• food additive E171;
• yellow-green colorant E 104.

In what form is available fluoxetine

Fluoxetine (patient testimonials are an indication of the high quality product) is manufactured by in different forms:

1. Capsules of 10 mg and 20 - are contoured cell sold in cartons. Optimal cost 110-125 rubles.
2. The tablets of 10 or 20 units per box were polypropylene. The price is 50-60 rubles.

Pharmacokinetics

Antidepressant perfectly absorbed in the gastrointestinal tract. Food, drink parallel reduces the absorption components. After 6-7 hours after the receiving means becomes maximum blood conc. Fluoxetine has a bioavailability of 60% and above.

Content antidepressant accumulates in tissues and penetrates through the BBB, participating in maintaining homeostasis and individual organs. In the liver metabolism is achieved by percolation processes inverse metabolize to form the active metabolite - norfluoxetine.

Derivation of the active substances takes place through the kidneys. Clearance is 94-704 ml / min, norfluoxetine - 60-336 ml / min. In renal insufficiency fluoxetine displayed with the same motion.

Due to the gastrointestinal tract beyond the order of 12% of the drug. Half-life of fluoxetine occurs about 2-3 days, norfluoxetine comes out of the body for 7-9 hours. When liver failure components of the medication displayed much longer the norm. During the period of lactation milk supplied 25% of the elements relative to serum.

Farmodinamika

Antidepressant acts as a stimulant and has timoanalepticheskoe effect. This blocks the reuptake of serotonin by neurons of the central nervous system.

Neurotransmitter is concentrated in the synaptic cleft, allowing the medication forces act strongly to longer inhibited postsynaptic neurons. Under the influence of drugs block the uptake of serotonin by platelets, the effect on the reuptake of dopamine occurs. Flouksetin - muskainovyh weak antagonist, histamine H1, and adrenergic 1 and 2 receptors.

application

Doctors recommended to take the drug by internal, regardless of mealtime. For people with various diseases and age category of the recommended dose rate is different.

For children up to 18 years

Babies take Fluoxetine is not recommended, since the active elements contribute to slower growth.

Adolescents receiving drug helps to cope with depression and OCD. Experts prescribe doses similar to adults. Health of the patient requires close monitoring in the initial phase of therapy with particular care. Person should be aware of the possibility of manifestation of the risks and side effects.

adult

To remove the depression in people in adulthood should begin receiving intense drug, observing the dosage of 20 mg / day. The best time of admission - early in the morning.

According to the advice of a doctor is allowed to increase the dose to 20 mg, the use of dividing in half, but not earlier than 21 days from the date of first use Fluoxetine. Dosage can be increased to a maximum of 80 mg per day. This happens with extreme caution only on doctor's advice.

For pregnant

Women during pregnancy or breastfeeding to take the drug is contraindicated. It affects the composition of milk during lactation, and in the fruit as a whole. Proper study of women during pregnancy have not been conducted.

A particular danger of the drug components can be held in the first trimester. If the woman still decided to take an antidepressant, you must carefully weigh the pros and cons of treatment. During labor in consequence of the bleeding can be opened.

for elderly

Doctors with extreme caution prescribe medication for elderly people. Daily rate should not exceed 40-60 mg. Discontinue the medication should be gradual, as well as the start (20 mg).

Contraindications Fluoxetine

Judging by the reviews of patients taking Fluoksetan, it can contribute to the violation of human organs.

It should be negligible consumption of the potent antidepressant if you notice the following symptoms:

• hypersensitivity to ingredients;
• a parallel course of treatment with monoamine oxidase inhibitors, pimozide, thioridazine;
• renal, hepatic failure;
• breast-feeding;
• pregnant state.

In limited quantities may take the medicine people diagnosed:

• diabetes;
• manifestation of convulsive disorders genesis;
• epilepsy;
• Pankersona disease;
• failure of organs such as the liver and kidneys;
• a sharp decline in body weight;
• predisposition to suicide.

Overdose

Doctors recommended to take the drug at 20 mg / day - minimal dose. Perhaps a gradual increase in the established limit, not to exceed 40 mg / day.

If the therapeutic dose is higher than the specified rate, there overdose with symptoms:

• heartbeat significantly quickens;
• are nausea vomiting;
• increased body temperature;
• concerned cramps;
• blood pressure is reduced;
• drowsiness and lethargy rises;
• can be hallucinations and delusions;
• It appears faint.

Symptoms of overdose are dependent not only on the misuse of drugs, but also on the initial state of human health.

If you experience one of these manifestations, it is necessary to provide first aid to the patient:

1. By drinking 1 liter of water and the pressure on the root of the tongue to induce vomiting, stomach wash. The procedure should be repeated several times and only if after the receiving means has been more than 60 minutes.
2. Use enterosorbent as activated carbon, smectite, and other Filtrum STI.
3. If the victim is unconscious, it must be put to one side and wait for the ambulance. These actions help prevent possible airway obstruction sunken tongue or vomit.

Side effects

Fluoxetine (patient responses are given to understand the seriousness of the effects on the body) may be adversely affected when taking an antidepressant in the wrong doses.

Namely:

1. In the central nervous system lesions doctors diagnose hypomania, mania, suicidal anxiety, irritable state, migraine, feeling of uncertainty in space, lack of sleep, convulsions, prostration.
2. Gastrointestinal tract accompanied by a decrease of appetite, nausea, vomiting, dry mouth, diarrhea, hypersalivation, disturbance of taste buds.
3. urogenital system can be affected with the accompaniment of incontinence or urinary retention, dysmenorrhea, vaginitis, fading fertility, male sexual dysfunction.
4. If it affects the other organs in patients clinically manifest allergic symptoms: unpleasant feeling of irritation, burning sensations and tingling, the formation of acne, trembling, fever, pain in joints and muscles, giperpotovydelenie, hyponatremia, tachycardia, weight loss, view.

Side effects are often observed at the initial stage of the course of treatment or at higher doses.

At the first signs of the above parameters must be rinsed stomach take adsorbents as activated carbon. If you experience convulsions, symptomatic therapy should be applied and use effective anxiolytic drugs.

drug interactions

Do not take means in parallel with MAO inhibitors (seleginin, procarbazine, furazolidone) and the precursors of serotonin, pimozide.

These elements during the interaction with this drug provoke an increase serotonergic transmission, dizziness, manic syndrome, emotional stress, convulsion, central nervous system, a sharp rise in blood pressure, fever, nausea, disorders, trembling.

It is possible to enhance the effect of reducing the functionality of the central nervous system when combined with an antidepressant alcohol or operating elements on the central nervous system. Also, the influence of hypoglycemic agents.

Adverse side effects and may increase upon receiving flouksetina with drugs, which include those elements with a high level of binding to proteins such as anticoagulants and digitoxin. Fluoxetine contributes to exacerbating action saharoponizhayuschih components.

Conditions and terms of Fluoxetine

Shelf life - 5 years. The location of the antidepressant should be available for children, the optimum temperature - 25 ° C.

Conditions of supply of pharmacies

Flouksetin (patient feedback confirm the effect of the drug on the body) can be purchased in pharmacies only prescription issued by the attending physician. On the shelves of pharmacies you can find a variety of different analogues of the drug in the composition which is the same active ingredient.

Some of them are provided in the table below:

Name	View release	recommendations	Dosage	Features
Flux	capsules	People with depression, obsessions, manic disorder, bulimia.	Optimum total dose - 20 mg per day may be increased to a maximum of 80 mg.	When receiving funds do not recommend watching and concentrating activities.
Adepres	pills	Special to the manifestation of reactive and severe depression, trivogoy, panic, post-traumatic symptoms.	Minimum Dosage - 20 mg, max - 50 mg per day.	To stop taking the drug, it is necessary each week to reduce the dosage of 0 mg.
Klokset	tablets	In severe depression, social phobias and panic.	The dose is increased gradually from 20 mg to 60 mg.	To get the effect of the drug, it is necessary to use at least 6 months.
Paroksin	pills	Inhibition promotes capture of 5-hydroxytryptamine neurons in the brain.	It is recommended to start receiving dosages of 20 mg per day, if necessary to raise gradually to 60 mg.	Young adults with severe mental disorders during treatment are at risk for suicidal behavior.

Antidepressants are safe for long-term therapy. Not addictive. Testimonials are subject to effective drug Fluoksetan, noted a positive effect on the nervous system of components, quick burst of energy and vitality.

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