Shed. Instructions for use, price, reviews, analogues

Prolyl - drug used in the treatment of infections in urinary system. According to the instructions he refers to the biologically active additives (Badam).

Shape and composition of the drug release

BAS produced in the form of enteric capsules prepackaged plastic vials, packed in cardboard containers. Each vial of 100 units. pills. Means consists of natural herbal ingredients.

Composition (per 1 mg per capsule):

• 27 extract of the leaves of kidney tea and sow thistle vegetable garden;
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• 24.5 leaf extract strobilanta curly;
• 24.5 herb extract filantusa niruri;
• 12.3 rhizomes Alang-Alang;
• 3.7 cubeb pepper fruit;
• 3.7 leaf extract Carica (papaya).

The additional agents include: turmeric (3.465), glucose (98.32), sodium bicarbonate (0.275) and methylparaben (0.04).

pharmacological properties

Strait, instructions for use which indicates that the additive is classified uroseptic means exhibits high efficiency in the prevention and in the treatment of urinary stone formation in system. Components additives have a diuretic effect, help eliminate inflammation and pain in renal colic.

BAD has diuretic properties, eliminating from the body metabolic increased formation of substances - urea chlorides. Relieves inflammatory reactions caused by prostaglandins. It has a decongestant effect and relieves inflammation in chronic hepatitis.

BAA exhibits the following properties:

• pronounced bactericidal activity (used as an adjunct in the use of antibiotics);
• Anesthetic effect;
• eliminates spasms in smooth muscle;
• reduces inflammation;
• diuretic effect;
• reduces disease recurrence.

The pharmacokinetic properties of the drug due to its constituent active components.

Active substances (properties):

• Fruits of pepper kubeba. The extract has antiinflammatory and disinfecting action. Relieves swelling and other reaction reduces inflammation in the urinary canals. It has a positive effect in lesions nephritis, urethritis, cystitis.
• Peel, leaves and fruit of CARICOM. Has a rejuvenating effect, it stimulates the immune system. Active substances reduce inflammatory manifestations, contributing to a reduction of allergic reactions. The extract activates blood circulation, which results in anti-edematous effect.
• Leaf Extract orthosiphon tychinkovogo. Active ingredients contribute to the activation of glomerular filtration, providing a pronounced diuretic effect. Is used in kidney disease, eliminate swelling, azotermii.
• Leaf Extract strobilanta curly. The formulations contain active components that promote dissolution and removal of mineral deposits in the urinary system. The extract has a diuretic effect, eliminating inflammation and spasm. Exhibits high regenerative properties in the presence of foci of inflammation in the tissues stimulates the local immunity.
• Extract of Alpinia officinarum. Component preparation exhibits higher antioxidant properties, reduces inflammation, reduces the generation of nitrogen oxides. The extract has a slight analgesic effect.
• Filantus niruri (grass). Thanks to the active components of the extract helps dissolve and remove the stones formed in the urinary tract area. Pronounced antibacterial effect can influence the pathogens causing the disease process.
• The extract of Garcinia mangosteen. It adjusts the metabolic processes in the body, thereby reducing appetite, prevents the formation of cholesterol and fatty acids.
• Sow-thistle extract vegetable garden. It shows a tonic effect, increasing the elasticity of the walls of the bladder. Relieves inflammatory reactions, restores and regulates processes mochevyvedeniya.

Pharmacodynamics and Pharmacokinetics

Strait, instruction manual which says that it has no pharmacodynamic properties passed certain tests related to its efficiency. Clinical tests, involving about 100 patients showed effectiveness as a means monotherapy pyelonephritis not associated with urinary obstruction in channels.

The first group, consisting of 65 people, which took place simultaneously with antibacterial drugs therapy given 2 tablets 2 times a day while taking food for 1 month. The second group of patients took standard therapy with antibacterial drugs.

Before the study, all patients had a weakness, pain in the lumbar. In 60% of cases there was an increase subfebrile temperature.

At the end of therapy with only a small part of the first group noted all leukocyturia symptoms (6.1%), in patients who did not take supplements, such pathology was found in 24% cases. Bacteriuria was observed in 7.7% (the first group) compared to 15% (the second group of participants).

Patients who were treated only with antibacterial drugs, pain in the lumbar region were observed in 24%. After 6 months post-treatment pain in the lumbar region of the first group of patients were identified in only 4% of patients of the second group like syndrome was observed in 27% of cases.

According to studies which took part in the 192 patients, the drug has a positive effect during ESWL (lithotripsy). The observations were carried out during the 3 years after the procedure. All patients were divided into 3 groups.

The 1st group included 75 men, which has been designated the classical treatment regimen includes receiving antibacterial and spasmolytic drugs. The participants of the 2nd group was appointed to the classical scheme of therapy in combination with a drug to shed.

Participants in the third group were further assigned to drugs belonging to the class of membrane stabilizing drugs in combination with antihypoxic means. After 3 years all participants ultrasound diagnostics was conducted, which revealed changes in the kidney tissue in 8.3% of cases.

In this case, the atherosclerotic lesion tissues were found in non-extensive lesions of the connective tissue.

Signs of nephrolithiasis during the observation period were identified:

1. Group 1 - 5.3%.
2. Group 2 - 2.5%.
3. Third group - 2.6%.

Such discrepancies in the figures are explained by the preparatory activities related to the conduct of lithotripsy, which help prevent the consequences caused by the shock-wave oscillations apparatus.

These studies have revealed that 95.8% of patients after 3 years of monitoring renal function remained normal. In other cases, the pathological changes were found. The presence of foci of inflammation were observed in 1 patient out of all 3 groups.

Indications

Prolyl, instructions for use which indicates the use of additives for different infectious and inflammatory phenomena in the kidneys and urinary system, shall be appointed by the attending physician, according to the detection of the disease.

Indications:

• inflammatory lesions in the bladder - cystitis;
• urethritis;
• venereal diseases;
• pyelonephritis;
• pyelitis;
• renal failure;
• Preparatory activities for the lithotripsy;
• prophylaxis of inflammations in the urinary ducts.

It can be administered as part of combination therapy in the development of urolithiasis in milder forms.

Contraindications

BAD is not used in the presence of allergic responses or and in the development of hypersensitivity to one or more components within the preparation.

Additional contraindications:

• cardiac insufficiency 3rd degree;
• atherosclerotic lesions, followed by heart rhythm disturbances;
• irritability, nervousness;
• disturbed sleep rhythms, insomnia;
• pathological disorders urethral process;
• elevated blood pressure.

The tool is also prohibited for use during pregnancy and breastfeeding. It is recommended to avoid the use of the presence of stones in the gall bladder, large diameters in order to avoid blockage of the bile ducts.

At what age can use the drug

The drug is not administered to children under the age of 12 years. Upon reaching 12 years of age the dosage and course of treatment is appointed for an adult.

Instructions for use, the dosage of the drug

Strait, instructions for use which indicates that the agent is a biologically active food supplements, should be taken inside during the meal. Standard application circuit is 2 capsules (or pills 5) 3 times daily at night.

Duration of therapy in this varies from 3 to 6 weeks depending on the disease. If necessary, the course may be extended up to 2-3 months based on evidence.

cystitis

Means, used in the complex therapy in conjunction with other anti-inflammatory and anti-bacterial drugs. This approach allows us to achieve positive results and achieve longer remissions.

BAA also allows you to reduce the frequency of relapses in patients with chronic form of the disease and to exclude the likelihood of a recurrence of the disease. Receiving means depending 5 capsules (with a dosage of 255 mg) 3 times a day for at least 3 months.

when urethritis

It is designated as an adjunct to lesion urethritis. Reduces the inflammatory response in the urethra, combats pathogens, reduces the appearance of puffiness. Take 2 capsules (with a dosage of 550 mg), 1 time per day. Recommended course - 1,5-2 months.

pyelonephritis

The drug is indicated for bacterial lesions of the duct system of the kidney - pyelonephritis. It can be used as an independent means or as an integrated approach. Treatment scheme: 2 capsules of times a day. The duration of treatment depends on the severity of the disease and usually is 1 month.

in the prevention

Dietary supplement is used as a prevention of kidney stones and preventing the development of infection in the urinary system.

Before use, you should consult with your doctor for preventive purpose of the course. The duration of prophylaxis is determined by an expert. Standard dosage regimen: 5 pills (2 tablets) 1 time per day.

Side effects

Typically, means is well tolerated by different groups of patients. Adverse reactions at the same time are extremely rare. May develop allergic reactions - itching, rash, redness, burning sensation on the skin.

Occasionally the application means having side effects in the form of dyspeptic disorders - nausea, vomiting, changes in the chair. Adverse symptoms disappear on their own after the withdrawal of the drug.

Overdose

Overdoses biologically active supplement has not been registered.

special instructions

Can be administered to patients in the elderly, those suffering from inflammatory processes that occur in the urinary tract.

drug interactions

Before using the drug in the complex treatment with other anti-inflammatory and antibacterial agents are advised to consult with your doctor. Information about drug interactions is absent.

analogs

Prolyl intolerance components can be replaced by other means with a similar composition or pharmacological effect. Before the use of a tool, you must familiarize yourself with the instructions for use and consult a physician.

• Biliurin. Antiseptic, manufactured in tablet form. Regulates metabolic processes in the kidney, restoring and normalizing fluid and electrolyte and acid-base balance. It has adaptogenic effect and exhibits antioxidant effect. The drug is made from natural raw materials of vegetable origin. Enriched with it a variety of essential oils. Treatment scheme: first week take 1 tablet 2 times per day. Then use 2 capsules daily 2-3 times a day. The duration of application of the drug depends on the shape and nature of the disease. It is not appointed during pregnancy and in children under 12 years old. Approximate cost of packing 1700 rubles.
• Uroprofit. It is a biologically active additive. It is produced in the form of enteric capsules. Made preparation from natural plant materials. It has diuretic, anti-inflammatory or antimicrobial action. As therapy prescribed 1 even 2 times a day. The average duration of treatment - 1 month. It is contraindicated during pregnancy. The cost of 460-560 rubles. per pack.
• NefroDoz. Combined plant origin. It has potent antiviral and antimicrobial activity. Appointed in infectious and inflammatory processes in the urinary tract, helping to cope with urolithiasis. It is recommended to take 1 tablet 2 times a day. The duration of treatment is 1 month. Prices in pharmacies vary in the range of 750-840 rubles.
• Uroforte Cranberry. Dietary supplement produced in 2 forms - tablets and liquid for internal use. The drug is indicated in adults and children over 14 years. It is a source of vitamins C and E and proanthocyanidins. It is not appointed during pregnancy and an increased sensitivity to the agent components. Take 1 time per day 1 tbsp or 1 capsule during the meal. The recommended course of treatment - at least 1 month. Cost (capsules) - from 560 to 620 rubles.
• Nephrophyt. The preparation plant. It is produced in the form of materials for making infusion. It shows diuretic and salureticheskim effect. It is intended for patients suffering from inflammation of the urinary system. Means helps to reduce painful sensations, elimination spasms, reduces edema. It can be used as an adjunct or as monotherapy. To prepare need 2 tablespoons means add 0.5 liters of boiling water and infuse, covered, for 1 hour. After this time the mixture was filtered and the use according to the doctor's recommendations. The standard dosage regimen for adults and children over 7 years: 0.15 l 3 times a day. Take the infusion should be half an hour before a meal. The course of treatment - 2 months. All of these courses must be made at least 2 times at intervals of 1 month. Cost per package (100 g) - 160-180 rub.
• Uroston. The preparation is made in the form of tablets having completely natural (vegetable) basis. Administered in an adjuvant in infectious and inflammatory diseases of the urinary tract. it is also intended for the prevention and treatment of stone formation in the kidneys. When infection is assigned to 2 capsules 3 times a day. When prevention of stone formation using 1 tablet 3 times daily. The duration of therapy is determined by the attending specialist. The cost of 530-560 rubles.
• Flavia. It refers to a group of plant origin combined. It is produced in the form of enteric tablets. It has anti-inflammatory, diuretic effect. Has a pronounced antibacterial and antispasmodic effect, is rich in flavonoids, volatile, essential oils. Recommended use: 1 capsule daily, 2 times a day. If necessary, or by the physician, the dosage may be increased up to 3 capsules daily. The course is determined individually based on the shape of the pathological process. The cost of the drug in drugstores of Moscow is from 540 to 560 rubles. per pack.

BUD replacement must be carried out only by the attending physician based on evidence and the individual characteristics of the patient's body.

Terms, conditions of sale and storage

Supplements should be stored in a cool and dry place, protected from the penetration of sunlight at a temperature not higher than +25 ⁰C. Shelf life - 3 years from the date of manufacture. Do not use after the expiration date printed on the package. Available without prescription.

Price in drugstores of Moscow, St. Petersburg, regions

BUD value may vary slightly depending on the region and sales, as well as on the basis of the distribution network of pharmacies. The tool can be purchased as in the specialized agencies, and through the online store.

Area, region	Dosage, packaging	cost of
Moscow, Moscow region	pill 225 mg	370-930 rub.
Moscow, Moscow region	capsule, 550 mg	544-801 rub.
St. Petersburg	pill 225 mg	373-811 rub.
St. Petersburg	capsules №60	693-748 rub.
St. Petersburg (suburbs)	pill 225 mg	474-680 rub.
Leningrad region	pill 225 mg	529-687 rub.
Novgorod region	pill 225 mg	480-679 rub.

Prior to use, the shedding should carefully read the instructions for use and consult with a nephrologist and a urologist.

Interesting video about the drug and its effectiveness Strait

Description of the drug to shed:

Analogue spilled - drug Uroprofit: