Painful periods - an actual problem for most women. This is due to a natural physiological process - uterine contraction. The modern market offers a variety of medications that can deal with the problem. However, gynecologists recommend Nimesil menstruation. Pain syndrome that occurs when menstruation in medical practice called algomenoreya. Painful periods adversely affect the physiological and psychological state of the patients.
According to statistics, every 10 women experience menstrual pain so severe that he could not lead a normal life. This condition is a disease and in this case it is better not to delay, it is necessary as soon as possible address to the gynecologist for help. Experts recommend at pains to take menstruatsionnyh Nimesil. This is one of the best drugs, relieves pain. The indications are also other diseases.
The etiology of menstrual pain
Menstruation - the monthly process of purification of the female body, in which the girls vaginal bleeding occurs. The first day of menstruation (regulation) is considered the beginning of the menstrual cycle. During menstruation uterine myocytes begin chaotically shrink spazmiruyutsya vessels, resulting in disturbed normal tissue trophism. All of these factors provoke the development of pain.
Within a month, the reproductive organ ready to fertilize the egg, the endometrium is covered by capillaries that at conception the embryo must provide trophism.
Intense pain during menstruation often occur against the background of the following pathologies:
- ectopic pregnancy;
- hormonal imbalance;
- impaired synthesis of progesterone;
- myoma;
- endometritis;
- oophoritis;
- endometrial polyps;
- adenomyosis;
- ovarian cyst.
types of ailments
Severe pain during menstruation often indicates the presence of health problems.
It can manifest itself in different ways:
- insomnia;
- depression;
- mood swings;
- severe fatigue;
- headache;
- discomfort in the region of the heart;
- nervousness;
- swelling;
- painful stomach;
- pain in the lumbar region;
- hypersensitivity of the breast;
- digestive system dysfunction (diarrhea, bloating, constipation and the like. d.).
Most often severe pain during menstruation observed in patients aged 13 to 35 years.
The mechanism of action of the drug and its effectiveness
Nimesil has analgesic, anti-inflammatory, antipyretic, and antirheumatic effects. The main active ingredient of the drug - nimesulide. Nimesil affects various body systems. It blocks pain receptors and inhibits the transmission of impulses to the brain.
Nimesil efficiency in the month due to the following factors:
- decrease in the concentration of histamine and prostaglandin in blood;
- optimize the functioning of glucocorticoid receptors;
- blocking the formation of reactive oxygen species in the cells of various tissues.
Nimesil at monthly pain - sufficiently effective agent which regulates the level of prostaglandins in the body. The chemical structure and biological effect of these compounds is very similar to the hormones of the adenohypophysis. These bioactive substances activate smooth muscle contraction, so the fairer sex appear cramping.
Often against a background of monthly observed abdominal pain. This is due to excessive accumulation of fluid in the body. Nimesil for painful menstruation helps to get rid of these signs. It stimulates the withdrawal of excess water from the body.
Nimesil for painful menstruation actively neutralize free radicals (of Hydrogen Peroxide, lipoperoksidny, hydroxide, superoxide anion radical) that provotsirutsiruyut destruction of cell membranes and development intoxication.
Nimesil interact with glucocorticoid receptors in combination with inhibition of prostaglandin production, it has a pronounced anti-inflammatory effect. For this reason Nimesil often used in gynecology, in particular for relief of pain during menstruation.
Dosage and form of the drug release
Nimesil discharged in the form of powder and tablets. Menstruation drink Nimesil allowed if the patient adheres to the instructions for use and doctor recommendations. Take Nimesil pain during menstruation need for 20-30 minutes before eating. When the monthly package nimesil should be diluted in half a glass of warm water and drink. The medicament is palatable and has a citrus scent. Nimesil menstruation well relieves pain and reduces the temperature.
The drug is rapidly absorbed in the gut, the maximum blood concentration reached in 2-3 hours after administration. Response to plasma proteins is 97%. Nimesil easily overcomes the blood-tissue barriers. Nimesil half-life of about 4-5 hours. All IVC drugs earlier period had a negative effect on the gastric mucosa. Nimesil not disrupt the operation of the mucous.
When severe pain is allowed to double the dosage of the drug. However, it is necessary to agree with the doctor, as Nimesil the maximum doses can be side effects. If the treatment Nimesilom therapeutic outcome not present, then it is better to refuse.
Drinking Nimesil menstruation during adolescence need the rate of 200 mg per day. Exceed the indicated dosage is not necessary, as there may be intoxication. Experts also do not recommend the use of Nimesil more than two weeks, but with painful menstruation is not for patients is very important. Girls are confronted with the earlier periods, should abandon nimesil and replace it with other drugs. To prevent severe pain, some doctors recommend drinking Nimesil a couple of days before the start of menstruation.
Contraindications
Nimesil as other drugs are as useful properties and contraindications.
These include:
- diabetes;
- nasal polyps;
- an allergic reaction to the drug components;
- bronchial asthma;
- pathologies of the digestive system;
- kidney and liver;
- arterial hypertension;
- stomach ulcer;
- Pregnancy and lactation;
- childhood;
- alcohol and drug addiction.
Side effects
Nimesil menstruation rarely causes side effects, but the probability of their occurrence can not be excluded.
Possible side effects:
- skin rash;
- itching;
- bleeding disorder;
- thrombocytopenia;
- anemia;
- nervousness;
- dizziness;
- hyperkalemia;
- infrequent urination;
- vision problems;
- bleeding gums;
- bronchospasm.
Before taking this medication the patient must be convinced that the etiology of pain is associated with menstruation, and not by other pathologies. Otherwise Nimesil only exacerbate the problem.
analogs
Nimesil helps with menstrual pain. In some cases, it can be replaced counterparts. It is desirable that all drugs prescribed doctor.
Menstruation can use the following medicines:
- Aktasulid;
- Prolid;
- Kokstral;
- Novolid;
- Anonymous;
- Nise;
- Aulin;
- Niemiec.
Nimesil - effective medicine to eliminate the unpleasant symptoms associated with menstruation. However, uncontrolled receiving the drug can lead to various complications, so before using it need to consult a medical practitioner.
sources:
Vidal: https://www.vidal.ru/drugs/nimesil
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = feea99ed-6bbf-4079-920f-ad79aeed5c36 & t =
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