Ceftriaxone relates to potent antibiotics which possess broad spectrum action. This is a unique tool to effectively cope with pathogenic microorganisms, which cause many dangerous diseases to humans. How many takes effect Ceftriaxone? What is the treatment schedule and dosage? These questions will help you understand the instructions for use and the attending physician.
Indications for use
The list of diseases in which the use of ceftriaxone, very long. This is due to its efficiency and unique ability to destroy the structure of membranes of pathogenic microbes, inhibiting their ability to grow and multiply.
Among the serious illness that can be treated with ceftriaxone, noted:
- bacterial meningitis;
- venereal diseases;
- peritonitis;
- osteomyelitis;
- inflammatory processes of infectious etiology urogenital system;
- LOR-organ lesions of bacterial origin;
- skin lesions;
- prostatitis.
With Ceftriaxone passes the prevention of postoperative complications in the background of a bacterial infection.
Specific recommendations for use of the drug
With great care using ceftriaxone for treatment of newborns with high bilirubin levels and patients with enterocolitis.
Throughout the course of treatment the physician should monitor the work of the kidneys and liver of the patient, as the elimination of drug metabolites occurs with the help of these organs. You also need to periodically conduct laboratory testing of blood.
Features of action Ceftriaxone
The preparation has antibacterial properties. It destroys pathogens process of cell blocks biosynthesis. Active component stops working all the important structures of the bacteria, thereby inhibiting its reproduction.
Action Ceftriaxone is aimed at the destruction of the different strains of bacterial agents, including dangerous pathogens. The drug does not respond to the action of an enzyme that is produced by bacteria. The medicine is also actively fights against anaerobic pathogens, Treponema pallidum.
Ceftriaxone is prescribed only after reliably establish the cause of the disease. The drug is not used if the agents of the disease group D streptococci steel, methicillin-resistant staphylococci and enterococci.
After intramuscular administration Ceftriaxone active component in a short period of time penetrates into the bloodstream, through which is distributed to the rest of the biological fluids and tissues. Medicine easily into the organs, all kinds of fabrics, fiber. With such dangerous diseases such as meningitis, drug penetrates into cerebrospinal fluid and inhibits the growth and reproduction of bacteria - meningococcus.
Ceftriaxone bioavailability after intramuscular administration is 100%.
Once in the body, Ceftriaxone starts to operate after a relatively short time. The maximum concentration after intramuscular injection Ceftriaxone detected already after 2-3 hours. If intravenous infusion of the drug reaches its peak concentration is already at the end of the procedure.
The half-life of the organism Ceftriaxone is 6-9 hours. Half the amount of antibacterial agent successfully coming out of the human body in the urine. Moreover, the drug does not change the structure completely. The second half of the drug is excreted in the bile. The drug is metabolized in the intestine and then forms an inactive compound.
Separately, doctors give advice on the compatibility of Ceftriaxone with alcohol. Antibiotics along with alcohol use is prohibited. This combination will provoke negative reactions that reduce the therapeutic effect:
- lowering blood pressure;
- heart palpitations;
- spasmodic pains in the abdomen and the epigastric region;
- labored breathing;
- dyspepsia;
- changes in skin color on the face and neck;
- headache.
In the event of an overdose of ceftriaxone it is used symptomatic therapy.
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