BRIEF DESCRIPTION preparations
Antibiotic Ceftriaxone sold in powder form for the preparation of solutions d / and intravenous injections. systemic metronidazole manufactured in oral tablets and p-moat d / intravenous administration.
Separately or simultaneously using these drugs in inflammation of the pelvic organs, ENT, abdominal, respiratory system and other structures. It is advisable to appoint, if the pathology provoked bacterial infections, sexually transmitted infections, protozoan parasites. Both drugs are used in therapy, pediatrics and adults.
Drug interaction preparations
Interaction of the active substances described in the manufacturers annotation of each drug. Prior to use, must be compared with ceftriaxone metronidazole according to the instructions.
The drug interaction of two drugs according annotations manufacturer:
- Metronidazole is compatible with the antibiotic azithromycin (macrolide). Can not be combined in the same syringe with cephalosporins Cefepime - these funds are pharmaceutically incompatible. During treatment, forbidden to drink alcohol-containing beverages;
- Ceftriaxone is not compatible with injection and infusion antibacterial solutions. Allowed concomitant use of an antimicrobial agent and two different antibiotics of group. During treatment, you can not drink alcohol.
Conclusion: Ceftriaxone belongs to the cephalosporin and metronidazole - to antimicrobial agents, and thus are both preparation for intravenous injections and can not be combined in a single container, as they are pharmaceutically incompatible. It allowed to turn in one day enter the / m or / in the two drugs, drink tablets, suppositories, gels with metronidazole.
Concomitant use of drugs
Metronidazole should not be diluted with a solution powder Ceftriaxone. Permitted combination of other forms of drugs in a treatment regimen. Their combined to broaden the activity spectrum of antibiotic and antimicrobial agents, enhance the therapeutic effect. Recommended by doctors course duration is 5 to 14 days.
How can both be treated with metronidazole and ceftriaxone:
- When pneumonia and uncomplicated course of the disease treatment are outpatient. Assign / m Ceftriaxone injection once a day, and receive Metronidazole 1 tablet four times / day. The dosage is calculated taking into account the age and weight of the patient;
- At moderate severity pathologies therapy tested in a hospital. Assign intravenous Ceftriaxone once a day and metrogil (metronidazole) + macrolide three times during the day. The dosage is selected individually for each patient.
You can not engage in self, self-assess dosage, the use of multiplicity. Improper use of drugs complicates the course of the disease may cause side effect dysfunction of kidney and liver.
analogues of drugs
Structural analogue (synonymous) Metronidazole systemic drugs are single component with the cipher ATC J01XD01. These include Metrolaker (India), Efloran (Slovenia), flags (France), Trykhopol (Poland), other antimicrobials containing only Metronidazole.
Absolute analogue Ceftriaxone is a powder preparation d / preparation of solutions for injections and infusions with ATX J01DD04 code. These tools include Lendatsin (Slovenia), Medakson (Cyprus), Movigip (China), Steritsef (India), other antibiotics containing only ceftriaxone. Same pharmacological action possessed by other III-generation cephalosporins such as cefotaxime.
sources:
Vidal: https://www.vidal.ru/drugs/metronidazole__18699
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 34a165f5-cd6a-4420-ac87-4d044867cd64 & t =
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