Modern antibacterials vary so high performance that may be mistakenly perceived by patients as a universal panacea. If you think so, you should not wonder why such a perfect drug azithromycin does not help.
To assign adequate treatment, it is necessary to establish the cause of the disease, and if it is an infection, and the identification of the agent. Make it could only be a doctor. And only he knows what to replace Azithromycin, if it does not help.
Pharmacological "portrait" of Azithromycin
Azithromycin popularity is due, primarily, its efficiency and gentle effect on the body. Thanks to perfect the pharmacological characteristics of the drug, its use has become topical in the development of many inflammatory processes and their complications.
Azithromycin - azalide antibiotic, a representative of macrolide derivative of erythromycin, but with improved characteristics. The main purpose of the drug - the suppression of vital activity of pathogenic microorganisms that triggered the disease.
The list of pathogens:
- Gram-positive and Gram-negative bacteria - staphylococci, streptococci;
- chlamydia;
- treponema;
- mycoplasma;
- ureaplasma;
- E. coli;
- anaerobes.
To understand why not help Azithromycin, it is sufficient to establish whether the causative agent is included in the above list.
As drug acts
Efficacy Azithromycin appears only under the action of its active substance on a certain kind of microorganism. The active ingredients have the ability to permeate the drug directly to the pathogenic cell by suppressing life activity and facilitating its destruction.
Once in the human body, Azithromycin quickly finds pockets of infection and is concentrated in the affected tissues, providing the best long-term exposure to pathogens. Furthermore, the drug and eliminates inflammation stimulates the activity of immune cells.
The drug is active in the treatment of any inflammatory processes accompanied by purulent lesions:
- purulent otitis;
- purulent tonsillitis;
- pneumonia caused by pneumococcus.
At the same time, Azithromycin is absolutely useless and does not help in the treatment of viral diseases and colds are not accompanied by bacterial complications.
In this way, if azithromycin does not help with angina, flu or bronchitisShould be replaced with the drug in a more suitable drug.
The reasons for the replacement of the antibiotic
Doctors consider it advisable to change the antibiotic to another drug if:
- Two days later after receiving means feeling better is not observed. Usually this means that the medicine does not help, because the causative agent is not sensitive to azithromycin;
- the patient came allergy to the drug;
- We have developed adverse reactions.
An important basis for the appointment of an antibiotic considered bacterial cause of the disease confirmation.
Also, many pathogens are not sensitive to the antibiotics penicillin group. In such cases, doctors recommend drugs macrolide to which belongs and Azithromycin. Conversely, if the macrolides do not help, it makes sense to take penicillin or other types of funds - lincosamides, cephalosporins, β-lactams.
In practice, cases where the bacteria are resistant to azithromycin and the drug does not work, it is rare.
It is also possible that azithromycin did not help with bronchitis or sore throat, if the patient does not follow the rules of reception facilities referred to in the instructions.
Minimum course of treatment Azithromycin is three days. However, to achieve the optimum result of antibiotic therapy for adults, doctors recommend a five-day course of treatment with azithromycin.
sources:
Vidal: https://www.vidal.ru/drugs/azithromycin__24064
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 464b69bc-52b8-420f-a2fd-5160efbe8523 & t =
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