Increased folic acid in the blood: the causes and what to do

Folic acid or vitamin B9 - essential vitamin for human body. Its production occurs in the intestine by bifidobacteria. However, the amount of acid generated is very small and therefore its main supplier is food.

Folic acid is involved in the synthesis of the amino acid, in the formation of healthy red blood cells, helping to supply our bodies with oxygen. It prevents the formation of blood clots and atherosclerotic plaques, and performs many other functions. Increase or decrease its concentration adversely affects the overall health of the body and cause a variety of negative phenomena.

That can cause increased folate concentration

Increased levels of folic acid in blood may cause the following situations:

• pathological disorders of the small intestine functions;
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• carrying out a vegetarian diet, or any other way the power that excludes meat products;
• lack of animal foods in the diet;
• overdose of vitamins and folic acid;
• reduced concentration of vitamin B12 in the body;
• pathologies arising after surgical intervention to remove the stomach (such as afferent loop syndrome).

Elevated levels of folic acid may provoke adverse effects:

• violation of the digestive system activity;
• disorders of the central nervous system, including anxiety, irritability, and others;
• impaired renal function (hyperplasia and hypertrophy of the kidney epithelial cell);
• a lack of vitamin B12.

When the primary symptoms improve vitamin B9 is necessary to conduct appropriate analyzes. Usually held simultaneous investigations, determining the concentration of folic acid and vitamin B12. Since the surplus can mask a lack of cyanocobalamin.

high index treatment is not usually performed. In rare cases it can assign specific diets that exclude products containing folic acid and increases its level.

Properties folic acid

Useful qualities of this substance for our body very difficult to overestimate.

Its main properties are:

• folic acid increases hemoglobin and regulates the functions of the hematopoietic system;
• activates the formation of new cells;
• It strengthens the immune system;
• involved in the production of amino acids (amino acids);
• It supports the work of the endocrine system;
• It normalizes the hepatic functions.

That is why the increase or decrease in its rules can cause serious disturbances in the human body.

Another very important property of folic acid is to reduce levels of homocysteine ​​when it is used. Homocysteine ​​- an amino acid, produced entirely in the human body. In the presence of various enzyme deficiency pathologies and required for its digestion of vitamins, this substance accumulates in the cells and blood plasma. Its increased levels may cause the development of cardiovascular disorders increases the pressure. Folic acid helps reduce the concentration of homocysteine, thereby reducing the risk of thrombosis and improves the general condition of the patient.

For the treatment of anemic conditions folic acid is used for a long time and successfully. The only exception, where it is not recommended intake of vitamin B9, are normocytic and aplastic anemia and anemia associated with deficiency of cyanocobalamin.

Gastritis with increased acidity of folic acid helps prevent inflammation of the stomach lining. Therefore, very often, doctors prescribe vitamin B9 at high acidity.

daily rate

Minimum daily dose of folic acid for the body is an amount of 0 05 mg (50 ug). In some pathologies which are characterized by a lack of vitamin B9, as well as during pregnancy, the needs of the body in this material increases.

analysis of the

To determine the rate of folic acid a special study of blood serum, Called biochemistry.

Determination of acid concentration is conducted by means immunohemilyuminestsentnogo analysis (IHLA) which is based on relations of antigens with antibodies. Currently, this method is the most accurate and sensitive (90%).

If the study determines that folic acid is reduced in the patient's blood, the doctor prescribes a special treatment.

Dosage and method of use

At deficiency of vitamin B9 is assigned to maintenance therapy:

• infants - 0.1 mg per day;
• child up to 4 years - 0.3 mg daily;
• to adults and children over 4 years old - 0.4 mg per day.

Duration of therapy is prescribed by the attending physician.

For the treatment of hypovitaminosis and vitamin deficiency in adults is used up to 5 mg of folic acid per day.

Children appoint an individual treatment regimen.

Contraindications

Therapy under reduced folate level has some limitations which are as follows:

• hypersensitivity to substances that are provided by means of the structure;
• lack of vitamin B12 in the body;
• Individual intolerance to lactose, lactose deficiency syndrome and the presence of glucose-galactose malabsorption.

The use of folic acid in the presence of the above-described limitations can cause serious adverse symptoms of the nervous and digestive systems.

conclusion

Folic acid - essential substance for the human body, is involved in a variety of processes that support it running.

Increased folic acid content can be caused by a number of factors associated with impaired functioning of the intestines, since it is there that its production. And with the absence in the diet of meat products.

Increased rate of vitamin B9 is usually not treated with drug methods. If necessary, the doctor prescribes a special diet that includes animal food.

Reduced levels of substance is normalized by a special treatment regimen, which is assigned after the survey.

sources:

Vidal: https://www.vidal.ru/drugs/folic_acid__33566
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 41e55b8d-98b2-40bf-8a79-92c1ecc3a912 & t =

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