The main active substance is betamethasone diprospana belongs to the group of corticosteroids. Let's find out what the means employed and the like are conducted diprospanom intraarticular injection.
pharmacological properties
The drug has potent anti-inflammatory, anti-allergic and immunosuppressive effects. This is due to a decrease in the concentration of immunoactive cells in the inflammatory foci, the expansion of the vascular lumen, and a decrease in the production of prostaglandins cause inflammation.
With intraarticular injection Diprospan passes rapid and complete absorption. The maximum therapeutic concentration of the active substance is accumulated for 20 - 60 minutes. This means that the relief of the patient's condition occurs very quickly.
Indications
Intra diprospana used for the therapy of rheumatic pathology, in particular arthritis.
For the treatment of allergic diseases, inflammatory, systemic, oncological and other measures should be carried out by intramuscular and intradermal injection.
Dosage and method of use
Diprospanom therapy scheme is assigned for each patient individually, depending on the disease and the general state of the patient's weight.
The drug is administered by intramuscular injection, if desired systemic delivery of glucocorticoids in the body, for example, for rapid removal of allergic reaction or inflammation. For the treatment of arthritis is made intra and periarticular administration. In the treatment of various skin diseases using intradermal injection (directly into the affected area).
Treatment begins with a minimal amount of drug. In case of stressful situations may require increased doses.
For the treatment of rheumatoid polyarthritis, osteoarthritis and osteoarthritis produced diprospanom intraarticular injection, at a dosage of from 0.5 to 2 ml.
According to the instructions, the recommended dosage Diprospan, for injection into the joints is:
- joints big size - from 1 to 2 ml of the suspension;
- medium - from 0.5 to 1 ml;
- small - from 0.25 to 0.5 ml.
Usually, after the procedure, the reduction of pain and restore joint mobility occurs within 2 - 4 hours. When prick intra Diprospan valid to one month.
Contraindications
Before starting Diprospan intraarticular injections, make sure no to the following restrictions:
- are hypersensitive to the presence of substances within the composition means;
- systemic fungal infections (mycoses);
- Verlgofa disease (idiopathic thrombocytopenic purpura) - intramuscular injection.
Side effects
During the intra-articular injections in very rare cases can occur joint infection causing infectious arthritis. Therefore, the presence of lumps, feverish states, enhancement of pain and inflammatory lesions at the injection site, not extending more than 3 days, consult a physician.
Complications after intraarticular administration diprospana may be expressed as a gain pain and inflammatory manifestations of not more than 2 - 3 days. This effect is called "postinjection crystalline synovitis" and is associated with gradual resorption fine crystals glucocorticosteroid. In order to prevent the development of pain medication injection is carried out in conjunction with anesthetics.
sources:
Vidal: https://www.vidal.ru/drugs/diprospan__264
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 747e2fbf-1f0d-400e-8816-5a9a78dedb11 & t =
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