Gout is a disease that affects the small joints due to improper metabolism of purine bases. Worsening of the disease is often seasonal. Treatment involves the use of nonsteroidal anti-inflammatory, and hormonal agents. Diprospan for gout used when the patient does not tolerate non-steroidal anti-inflammatory drugs. Diprospan injected into the area of the small joints.
Pharmacological properties, shape Diprospan
Diprospan refers to the glucocorticosteroid drugs. Medication well helps reduce inflammation. In autoimmune diseases the medicament reduces the immune system, which prevents rejection and destruction of autologous tissue. Cells of the immune system (T-cells, killer cells) become less active.
In diseases of the joints of the drug reduces inflammation in joint tissue, reduce morning stiffness, prevents the occurrence of contractures. In allergic pathologies inflammatory reaction goes faster, it reduces swelling. All of these effects are attributed to the glucocorticoid exposure.
Diprospana active components (1 ml) are:
- betamethasone dipropionate 6.43 mg (5 mg of betamethasone);
- betamethasone sodium phosphate 2.63 mg (2 mg betamethasone).
The medicine can be administered intramuscularly, orally and around the joint, intradermally into the tissues. Intravenous and subcutaneous administration is contraindicated drug. Analogue Diprospan is Kenalog. Price Diprospan (1 mL) in St. Petersburg, is 192-225 rubles.
The concept of gout
Gout - a pathology which is characterized by the accumulation of uric acid salts in the joints and in the renal tissue. The incidence of gout is 0.1%. The disease is recorded everywhere. Pathology often found in middle-aged and older patients. The male population of the disease occurs 20 times more often.
Clinical manifestations of gout characterized by severe arthritis with severe pain. In patients with marked swelling of the small joints. Exacerbation replaced asymptomatic period. A characteristic feature of chronic forms are nodules (tophi), chronic arthritis, osteoarthritis, as well as kidney damage.
The first attack usually begins at night. The disease can cause fractures, alcohol, fatty foods, hypothermia. The first affected the metatarsophalangeal joint of the thumb. The patient has a fever. The joint is strong swells, the skin over the affected area becomes red. While driving there is very severe pain. After a 3-10 day symptoms fade, the joint starts to work again.
gout treatment
For gout therapy using non-steroidal anti-inflammatory drugs (NSAIDs). The patient is required to appoint a diet that does not contain purines. If the patient has contraindications to NSAID purpose, the treatment is carried out by means of glucocorticoid hormones. The main ones include prednisolone, methylprednisolone. After the relief of gout corticosteroids gradually overturned.
Systemic corticosteroids often cause rebound syndrome, as well as adverse events. Because of this, during the treatment of the patient is observed in the hospital. To prevent rebound syndrome Colchicine is permissible to use in small doses (1-2 mg).
In addition to systemic corticosteroids permissible use of local corticosteroids. Excellent preparations for local use and Kenalog is considered Diprospan. Both have the form of a slurry. Treatment of gout diprospanom implies its introduction intramuscularly or into the joint cavity.
When gout Diprospan administered intramuscularly as possible, but often use topical administration. Diprospan a drug with sustained action. The drug has a very small crystals, so if intraarticular injection diprospana patient hardly feels pain. The drug is injected into the joint cavity. After the introduction of the effects of the injection begins in 3-4 hours. Continuing therapeutic effect for about 3 weeks. Gout on his feet injections Diprospan allow long to maintain the patient's ability to work, as well as to reduce the frequency of exacerbations of the disease.
conclusion
Injections Diprospan gout help improve quality of life. In addition to drug therapy for the patient it is very important to follow a diet. This will reduce the accumulation of uric acid in the tissues of the joints and kidneys. You should not self-treat disease. When the gout symptoms should immediately seek medical attention.
sources:
Vidal: https://www.vidal.ru/drugs/diprospan__264
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 747e2fbf-1f0d-400e-8816-5a9a78dedb11 & t =
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