Afobazol - antianxiety drug, manufactured as tablets. There are various tablet forms of drugs that need to be dissolved in water, swallow or kept under the tongue. This article will try to understand, Afobazol need to drink or dissolve. A simple question, as numerous reviews, recommendations and descriptions provide different information.
Release form of the drug
Afobazol discharged Russian pharmaceutical company "Pharmstandart-Leksredstva" in the dosage form in the form of uncoated tablets. Each tablet Afobazol contains 5 or 10 mg of active substance fabomotizole and a large amount of auxiliary components.
Pharmacokinetics Afobazol
To understand how best to take the pharmaceutical preparation, it is necessary to analyze its pharmacokinetic parameters. Afobazol absorbed in the lower intestine. There is no evidence that the drug is well absorbed in the mouth, so use Afobazol under the tongue unfounded. The drug is well distributed to organs and tissues with intensive blood flow.
The main metabolism occurs in the liver hepatocytes. Means starts to operate in a week after the first pill. Time for which the output from the body half of the active drug components - at least one hour. Output as the digestive and excretory system.
Indications for use
Afobazol indicated for pathologies such as:
- Anxiety, generalized nature;
- Fatigue, irritability, headaches, unclear localization;
- Upset adaptive reactions, acute reaction to a stressful situation;
- sleep disturbance, insomnia, anxious depression;
- PMS in women of reproductive age;
- withdrawal symptoms in people who abuse alcohol.
As a means of further sipmtomaticheskoy therapy for pathologies:
- Bronchial asthma, especially related to the attacks in response to stressful situations;
- Functional bowel disease;
- Libman-Sacks disease;
- Coronary heart disease;
- Arterial hypertension;
- Violation of rhythm and conduction of the heart;
- Diseases of the skin, malignant disease.
Sublingual tablets are usually taken in emergency situations. As can be seen from the list, there is no urgent indication for use for Afobazol. All of these diseases are chronic and long-term proceed. The effect of the Afobazol does not develop immediately, on average a week, which also makes unreasonable the drug under the tongue and resorption.
admission rules
The drug is taken orally after meals. Afobazol washed down with water, without chewing, not dissolving. Tablets bitter taste, so that they dissolve not only unreasonable, but also frustrating.
The recommended daily dose - 30 mg. The daily dose should be divided into three stages: in the morning, afternoon and evening of 10 mg after meals. Course admission is prescribed individually depending on the indication and on average three weeks. If necessary, after consultation with the attending physician dosage and duration of the course can be increased.
conclusion
Even after a brief study of the pharmacokinetic parameters and the basic information about the drug, it is possible to answer the question: to drink or dissolve Afobazol? Absorption of the drug in the lower gastrointestinal tract, bitter taste of the tablets and formal instruction from the manufacturer prove that Afobazol need to swallow with water, and not dissolve and do not keep under language.
sources:
Vidal: https://www.vidal.ru/drugs/afobazol__8918
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 371de6b3-e920-4e80-9e9a-7a458f7c9a89 & t =
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