General information about anxiolytics
To navigate, which is better: Afobazol or Atarax, it is necessary to compare the pharmacological properties and pharmacokinetics of drugs. Afobazol affects subcortical structures (limbic system, midbrain), acts on receptors that are sensitive to inhibition mediators.
It refers to the group of benzodiazepines. The effect is not immediate, but only after a few days, helps to fight chronic stress.
Atarax - diphenylmethane derivatives. The drug is called "soft" tranquilizer. In addition to the anxiolytic, sedative, antihistamine, antiemetic action. It can be used with appropriate related pathologies. It operates in half an hour. It is advisable to assign Atarax patients with bronchial asthma, allergic diseases, as medicine has bronchodilator activity, reduces the intensity of itching, rashes eliminates skin.
Both drugs effectively perform the main task - to reduce the level of anxiety, eliminate unfounded fears and phobias, increase the ability to think, memorize, improve attention. And Atarax Afobazol penetrate the natural barriers of the body: the blood-brain, placenta and blood-milk. Ataraxum half-life is considerably longer than Afobazol that causes a longer effect of the first drug.
The differences in indications for
Afobazol and Atarax prescribed to treat:
- Anxious syndrome, physical and mental stimulation, a sense of tension;
- Refusal of alcoholism, smoking at long time (to ease withdrawal symptoms);
- Stress, neurosis, neurasthenia, phobias, panic attacks.
Atarax, moreover, can be used as a means of premedication in stationary conditions, as well as to reduce the severity of itching.
Differences in contra
Afobazol and Atarax is prohibited during pregnancy, during labor and delivery, breastfeeding, with malabsorption syndrome and malabsorption glucose-galactose, with a deficit of enzymes metabolizing galactose. Additional contraindication for Atarax - porphyria. This drug is also quite a lot regarding the prohibition to receive: constipation, increased pressure inside the eye, convulsions, heart rhythm, difficulty in urinating.
Side effects
Afobazol has fewer side effects than Atarax. Adverse reactions after taking Afobazol can be represented by minor allergic manifestations, individual intolerance medicament components. Atarax may depress the central nervous system function or paradoxically stimulate it.
Possible symptoms such as dryness of the mouth, micturition difficulties, constipation, decreased performance, fatigue during the day, the systemic nature dizziness, hyperhidrosis, reducing blood pressure, increased heart rate, nausea, dyspepsia, fever, increased hepatic level enzymes.
Mode of application
Afobazol drink three times a day to 10 mg. Atarax also divided into three stages: 12.5 mg in the morning and at lunch, 25 mg in the evening, 30 minutes after dinner. For premedekatsii drug is administered one hour before surgery intramuscular injection at the rate of 1 mg per kilogram of patient body weight. For the treatment of pruritus recommended dosage is 25 mg. Take tool can be up to 4 times per day. Duration of treatment establishes an expert.
Manifestations of overdose are more pronounced after the poisoning Atarax than afobazole. The probability of overdose is increased if you drink together Atarax and Afobazol as drugs potentiate the action of each other. Symptoms: vomiting, diarrhea, muscle twitching, seizures, hallucinations, loss of consciousness, delirium, heart rhythm disturbance, drop in blood pressure.
Interaction
Combining Afobazol and Atarax not recommended because both drugs have similar anxiolytic effect and reinforce each other's action. The result is a paradoxical effect of activating the central nervous system. Medicines taken separately, the choice of drug is better to trust the doctor that the appointment of Therapy is based on history, complaints, course of the disease, results of examination and medical standards.
conclusion
Based on the pharmacological properties of drugs, one can say that Atarax Afobazol stronger. After receiving Ataraxum effect comes quickly. The drug is useful in concomitant allergies. At the same time, the drug has more side effects and contraindications than Afobazol less safe.
Afobazol compatibility with Atarax - means forbidden to take at the same time. necessary to pick another drug (e.g., Grandaxinum, Phenibutum or other analogues) In case of insufficient effectiveness of a medication, drugs and drink simultaneously. Failure to comply with the instructions for use can lead to negative consequences, aggravate the disease, worsen the prognosis for recovery.
sources:
Vidal: https://www.vidal.ru/drugs/afobazol__8918
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 371de6b3-e920-4e80-9e9a-7a458f7c9a89 & t =
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