Afobazol or tenoten: which is better, and whether it is possible at the same time, a comparison

Comparison of anxiolytic actions

The difference between Tenotenom and afobazole lies in their composition and differences affect the body. The first preparation has a combined effect, immediately belongs to two groups: neyrometabolicheskie stimulants (nootropics) and antianxiety agents. Afobazol also only refer to anxiolytics. Therefore, these are the same drugs in the ATC only one code: N05BX.

Table comparing the readings to the use of anxiolytics and Afobazol tenoten:

Nosology	disease code ICD-10	afobazol	tenoten children	tenotome	Explanation of nosology
Somatic symptoms of disease with anxiety	―	V	The emergence of anxiety in asthma, COPD, lupus, cardiac ischemia or arrhythmias, hypertension, irritable bowel syndrome and other somatic pathologies.
asthenic disorders	F06.6	V
Personality and behavioral disorder	F07	V
somatoform disorder	F45.9	V
abstinence	F10.3, F17.3	V	Disorder caused by alcohol consumption or smoking (hangover, nicotine abstinence).
anxiety disorder	F41.1, F41.9	V	V	V	Violation generalized or unspecified (phobic neurosis, panic attacks, anxiety).
Anxiety and depressive disorder	F41.2	V	Signs of a mixed type.
Reaction to stress or related violation of adaptation	F43.0-F43.9	V	V	The effects of stress and depression.
Neurasthenia	F48.0	V	V	V
Other disorders NA	V	V	Psycho-emotional strain.
Unstable personality disorder	F60.3	V
Attention deficits, behavior, activity	F90.0, F91	V	Depression, neurosis or school with lethargy, lack of attention, hyperactivity syndrome.
Kleine-Levin syndrome	G47.8	V	A disease in which a person is sleeping more than 18 hours a day.
Violations of the vegetative NA	G90.0-G90.9	V	V	V	IRR and other types of dystonia, autonomic lability.
Cerebrovascular disease and its consequences	I67.9, I69	V	Disorders of blood circulation in the brain, hypoxia, changes in blood vessels.
Cognitive and psycho-emotional disorders	R41.3.0, R45.0-45.4	V	V	Irritation, apathy, anxiety, memory loss, demoralization, anxiety, anger, emotional arousal.
Emotional distress in children	F93.9	V	Neurotic syndrome.
PMS	N94.3	V	The deterioration of mental and emotional mood due to changes in phase of the cycle.
Violation of adaptation to the change in lifestyle	Z60.0	Jet lag disorder or adapting to a new job after the move, and so on.
Injuries and their consequences	T14, T90, S06	V	Or unspecified intracranial injury.

Note: in practice, doctors prescribe Afobazol under the same cognitive and neurotic disorders that tenoten. Preparation with fabomotizole 2/3 patients normalize psycho-emotional state, improves the memory and ability of concentration.

BRIEF DESCRIPTION tenoten

tenotome - a homeopathic drug with nootropic and anxiolytic action. It is produced in the form of lozenges. The main component of the composition are the antibodies to brain-specific protein S-100 at a dosage of 3 mg or an active form thereof in a volume of 10⁻¹⁵ nanograms / gram. Auxiliary is 0.03 g MCC, 0.003 g of magnesium stearate and 0.267 g of lactose.

The therapeutic properties of tenoten:

• protivoamnesticheskoe (improves memory);
• nootropic (normalizes metabolism in the brain);
• neuroprotection (restores neuronal cell structure);
• antistress and protivodepressivnoe (NA increases endurance to stimuli);
• anxiolytic;
• protivoastenicheskoe (function restores depleted neurons);
• anti-hypoxic (eliminates the effects of oxygen starvation of the cells).

Developed two types of drugs - "tenoten children" and for the treatment of adults. However, when comparing formulations instructions do not differ in composition or dosage of the active substances and excipients. Direct (structural) Proproten analogue is 100, Antibodies to brainspecific protein S-100, Antibodies to S-100 brain-specific proteins.

BRIEF DESCRIPTION Afobazol

afobazol - it is a tranquilizer with anti-anxiety and neuroprotective effects. It is made in the form of uncoated tablets for ingestion. The active substance is fabomotizole (fabomotizole), the dosage is 5 mg, 10 mg. Auxiliaries protrudes 0.048 g of potato starch, 0.04 g of MCC, 0.0485 g of lactose, 0.007 g of the middle molecular povidone, 0.0015 g of magnesium stearate.

The therapeutic properties of Afobazol:

• reduces concern, irritability, anxiety (anxiolytic effect);
• removes or psycho-emotional tension (normalizes mood, relaxes, eliminates insomnia);
• removes somatic symptoms;
• excludes autonomic NS disorders (eliminates vertigo, dryness of the mouth, sweating);
• It improves memory (antiamnesic) and concentration;
• normalizes asthenic manifestations of personal nature.

Afobazol used only in the treatment of adult patients after 18 years. It is a structural analogue of an infusion concentrate Neyrofazol.

Comparison of contraindications and side effects of anxiolytics

Children tenoten not allowed to give the child up to 3 years. List of other restrictions identical contraindications for adults.

Afobazol or tenoten for adults can not be used in patients under 18 years, pregnancy, hypersensitivity to the composition of drugs, the presence of galactose intolerance, lactase deficiency, malabsorption syndrome monosaccharides. Lactating women are allowed to take the money only after the transfer of the child on artificial feeding. Breast feeding is resumed two weeks after completion of the course or afobazole Tenotenom.

Both drugs can provoke a rash or other allergic reaction. Afobazol differs from tenoten other side effects. fabomotizole treatment rarely causes cephalalgia (headache). Such a reaction to Afobazol disappears on its own in the 1-5 days of therapy. Upon receiving tenoten may appear diplopia. Vision is restored after 10 minutes itself.

Advantages and disadvantages of anxiolytics

Neither tenoten nor Afobazol not addictive to their action, Dependence syndrome and in connection with the abolition of the drug. The benefits include the safety and lack of hepatotoxicity, rare occurrence of adverse reactions, a large percentage of patients the body's response to treatment. The advantages of the opportunity to belong to a long continuous reception: Afobazol allowed to drink 3 months and tenoten - six months.

The disadvantages include razreklamirovannost drugs, the market value of high, more than 20% of the futility of treatment. Questions from doctors is the lack of evidence (suspicion of the placebo effect) and the lack of description of side effects. Many patients and pediatric therapy complain of weight gain, increase in severity of excitability, irritation, insomnia, including in comparison with other drugs, although such effects are not specified in the instructions Afobazole, tenoten.

Comparison of the results of clinical trials

You can compare Afobazol tenoten and also on the results of testing these tools developers. Fabomotizole acts on Σ₁ R (sigma receptor) in the brain stimulates neurons and increases their energy potential. This complex influence Afobazol restores the sensitivity of nerve cells to the CNS inhibitory neurotransmitters, thus relieving stress NA. Subject to the dosage of 30-60 mg / day in humans do not develop sedation (sleepiness) and can safely drive vehicles or operate machinery.

The results of research Afobazol:

• within an hour after receiving the blood reaches the peripheral areas of the body;
• excreted for 34-160 minutes;
• first effect patients noted after five days of treatment at a dose of 30 mg per day;
• after therapy Afobazol anxiolytic effect lasts up to 14 days;
• overdose somnolence;
• 70% of patients participating in testing, stable effect occurred after 4 weeks of use.

WHO specialists investigated the pharmacological action and safety Afobazol for the body. Based on the test results, they decided to include the substance in the ATC directory and gave him a separate cipher N05BX «fabomotizole». Therefore, in 2015, officially belongs Afobazol anxiolytics and used according to the protocol of treatment of neuropsychiatric disorders.

Tenoten agent enhances activity in the brain protein S-100, which normalizes the information process, its metabolism in tissues, increases neuronal plasticity. The studies were conducted only by developers of the drug in the scientific center of VP Serbian. Within a month, we tested 80 people over the age of 18, except for pregnant women, lactating women. on the efficacy and tolerability of a report drawn up in 2004 on the basis of a patient survey of adverse events and comparison with weekly entries on the Hamilton scale, HAM-A, the STAI, SAN.

Test results tenoten:

• calming effect was noticeable after 2 weeks of treatment;
• when used in less than 2 hours before bedtime, deteriorating sleep process;
• 5 patients having adverse reactions, including no effect;
• 75% of those taking the means to the end of 28 days has passed anxiety.

Tenoten documents and did not pass the WHO experts, so there is no complete test results according to their standards. Active substance "antibodies to brain-specific protein S-100" is assigned a single code in ATH, drug with its contents are not means of the first series, should not be treated only Tenotenom.

Evaluating the effectiveness of the choice of means

In the treatment of diseases with the presence of anxiety is better than an adult to take Afobazol tenoten. Action fabomotizole and safely explore the developers, clinicians and WHO experts. It is compatible with ethanol increases the anticonvulsant property anticonvulsants that can be successfully applied it in alcohol withdrawal. The active substance Afobazol gently eliminates symptoms of somatic diseases 12-ultradisperse colon, gastrointestinal tract, ganglion, the cardiovascular system. Tenoten - homeopathic remedy from the disputed therapeutic efficacy.

Permission is granted to drugs action complement homeopathy in the treatment of anxiety caused by the violation of cerebral circulation, and for the prevention of its consequences. With prolonged use instead Afobazol tenoten be effective. But monosredstvo it is used after drug therapy.

If the result for the comparison of the stimulatory effect of anxiolytics, it will be stronger drug tenoten: his latest appointment must be no later than 120 minutes before bedtime. Afobazol also allowed to drink at night, because it has a slight stimulating effect, and it is better to drink with sleep disorders.

Combined use of anxiolytics

In medstatistiki on May 2018 not recorded adverse reactions considered anxiolytics interaction with other drugs substances. Therefore, treatment is allowed and means Afobazol tenoten simultaneously. Combined use fabomotizole and antibodies to the protein S-100 expands their action spectrum, amplifies anxiolytic, sedative effect. Most often used to treat long-term anxiety, the strong decline of memory or attention.

Attention: it is not necessary to use tenoten and Afobazol together! Tablets fabomotizole drink no later than 40 minutes after meals three times a day. Tenoten resolves the 1 / 4-1 / 2 hours before eating.

According to doctors

By similarity tenoten Afobazol and include their use in organic diseases of the nervous system, stress, autonomic disorders. These drugs should be used if a violation of the National Assembly functions or progression of the disease is accompanied by anxiety, insomnia, memory impairment, emotional lability, dizziness and the like manifestations. Soothing effect appeared to initially receive them, further appointed sedatives, e.g., Novopassit.

The difference is that tenoten belongs to homeopathic remedies and Afobazol - to tranquilizers. The drug to antibody-based brain-specific protein S-100 can be used for preventive purposes. A drug with fabomotizole appointed in the course of treatment to eliminate anxiety and other consequences NA disorders in people 18 years of age.

In the opinion of neurologists and other physicians in moderate disorders Afobazol effectively use complex with medicines given in a report of treatment of disease detection. Tenoten as homeopathy and other funds are used only for the prevention or as an auxiliary drug for therapy. Its active ingredient enhances the action of essential drugs.

Many doctors are practicing a combination of medical treatments and alternative medicine. They allow the combination therapy Tenotenom afobazole and if the patient tolerates both substances, increasing the efficiency of resources, enhanced anxiolytic and sedative property.

Useful homeopathic medicines administered to humans at an alarming suspiciousness and susceptible to auto-suggestion. In the absence of pathological factors is important more than a placebo effect and the safety of such funds. In these cases will help tenoten subject dosages.

What drug to give an advantage - to say the physician. Tenoten with afobazole not so long ago used in neurology and psychiatry. If their use for other purposes, without prior examination, with inappropriate dosage form of the disease - a pathology complicated psychoneurotic, autonomic disorders.

sources:

Vidal: https://www.vidal.ru/drugs/afobazol__8918
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 371de6b3-e920-4e80-9e9a-7a458f7c9a89 & t =

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