The composition and dosage form
The active drug substance - cefixime, 0.4 g Auxiliary components are flavorants, cellulose, silicon dioxide, magnesium stearate.
For children it is realized in the form of granules, which is prepared from a slurry. Vial thirty or sixty grams of granules. 5 ml of the finished suspension contains 100 mg of the antibiotic.
Supraks sold for 1, 5 or 7 tablets or capsules in blister, Two blister packaged with instructions from the manufacturer. Available on medical prescription.
medicinal properties
Supraks contains a semisynthetic antibiotic from the group of origin of the new-generation cephalosporins. It exhibits an active effect against bacterial agents. The mechanism of action involves a violation of the integrity of the bacteria cell membranes. Resistant to beta-lactamase a large spectrum of bacteria.
Supraks exhibits activity against streptococci, Klebsiella, Salmonella, Enterococcus, Clostridium, enterobacteria, and a range of other infectious agents.
Peak blood levels are achieved within 4 hours after application
. The half - about three hours, and excreted in urine, half - unchanged. When insufficiency of the kidneys half-life is doubled, in patients with liver disease during excretion rises to 6.5 hours.The etiology of sinusitis
To determine whether to treat sinusitis Supraksom effectively, it must be weighed spectrum antibiotics with potential agents of maxillary sinusitis.
The main role in the development of sinusitis is playing pathogens, including bacteria:
- streptococci;
- staphylococci;
- Haemophilus influenzae.
Viral diseases can also encourage the development of sinusitis as a complication. This happens when a virus infection of influenza, parainfluenza, rhinoviruses, coronaviruses.
Cause the development of sinusitis can and pathogenic fungi, such as Aspergillus, Mucorales, Candida. Factors contributing to the development of sinusitis in humans are such states:
- reduction in immune response;
- presence of congenital anomalies of the nasal sinuses or acquired curvature of the nasal septum;
- growths in the nasal cavities: polyps, cysts, tumors;
- respiratory viral infections, allergies;
- dental infections, sudden pressure changes.
Often there is penetration of the filling material into the cavity at low as treatment of the upper jaw teeth. In this case, the filling material can be sterile, but still trigger the development of infection. When sinusitis triggered by tumors or foreign bodies, they must necessarily be removed.
Cephalosporins are antibiotics of choice in the sinus, along with penicillins, macrolides and azalides. In case of intolerance to medication groups doctor selects from another analogue, carefully considering the spectrum of activity.
The clinical picture of the disease
Symptomatic sinusitis complex consists of general and local symptoms. By the local symptoms of sinusitis include such manifestations:
- constant nasal congestion;
- nocturnal snoring and daytime pant;
- During mucus from the nasal passages;
- watery eyes, lack of sense of smell;
- uncomfortable pressure in the maxillary sinuses;
- pain in the nose and in the maxillary sinuses;
- headaches in the temporal lobes, worse when moving head.
When the first symptoms it is important to see a doctor and begin diagnostics. Chronic sinusitis is dangerous all the stronger exacerbations. In severe cases, complications are accompanied by purulent lesions of the bone with the penetration of the pathogen in the meninges. Such additional complication is accompanied by symptoms of meningitis and Severe states, including death in the absence of any treatment.
Efficacy and indications Supraksa
In the case where precipitated bacterial sinusitis agents, antibiotics are the drugs of choice. Supraks sinusitis due to the wide range of activities eliminates the root cause - bacterial pathogen pathology.
It is important to note that in those situations where the cause was a fungus or a virus infection, Supraks will be ineffective. In such cases, appointed antimycotic and antiviral drugs.
For this reason, pre-conducted bacteriological culture from the sinuses to determine the microflora. In a healthy person in the maxillary sinuses no microflora - they are sterile. After determination of the pathogen or infectious disease audiologist designate Supraks or other drugs, depending on the specific cause.
Supraks appointed the following pathologies:
- upper respiratory tract infections;
- infections of the nasopharynx, oropharynx;
- acute and chronic urinary tract infectious disease.
Recommend Supraksom treatment of sinusitis or other infectious pathologies can only physician. Independent choice of antibiotic dangerous severe side effects and decrease the overall immune response.
Dosing and dosing
When sinusitis adults to take Supraks recommended therapeutic doses: adults and a child of twelve years can be taken no more than 0.4 grams per day for one or two doses.
Tablet previously dissolved in half a glass of water or drink entire, Then washed down with water. When using the solution you need to drink it immediately after preparation. Application Supraksa is independent of food intake. A tablet can be divided into two doses.
Duration of treatment Supraksom depends on how hard it passes sinusitis and if it is running. After all disappear bacterial lesion symptoms, take Supraks need at least another one or two days.
Recommended to prevent complications such courses of therapy Supraksom:
- the associated upper respiratory tract infection - up to ten days;
- lower respiratory tract infections - up to two weeks;
- otitis media, sinusitis - from ten to fourteen days.
Treatment of pathologies caused by group A streptococcus, Supraksom not less than ten days should be done to prevent complications in the urinary system and the musculoskeletal system.
Patients with diseases of the urinary system should be administered by means of treatment of sinusitis Supraksa with caution, the daily dosage in this case was 0.2 g and is received at a time.
Suspension
When sinusitis in children Supraks tablets allowed by the age of twelve, at a younger age - in the form of a suspension. The volume of the drug depends on the age and approximately:
- from six months to a year - 2.5-4 ml per day of finished slurry;
- from 2 to 4 years - 5 ml per day;
- from 5 to 11 years - from 6 to 10 ml per day in two doses.
Dosage Supraksa sinus calculated at 8 mg per kilogram body weight of the child. The calculated dose is taken once or divided into two doses. For simplicity, the application Supraksa in two stages can be considered prior to each use a dosage of 4 mg per kilogram of body weight. In the case of two times daily important to keep an equal time interval between doses Supraksa - twelve hours.
multimodality therapy
Preparation Supraks sinusitis cures due to its antibacterial activity but also symptomatic drugs may be present as part of a combined treatment. They enhance the effect Supraksa facilitate the patient's condition and promote a speedy recovery.
Combination therapy includes:
- antibiotics that eliminate pathogens;
- probiotics, beneficial bacteria podselyayuschie and enhancing local immunity;
- vasoconstrictor and anti-inflammatory drops;
- emollient droplet to restore the nasal mucosa;
- washing with sinuses antiseptic solutions and antibiotics.
The latter procedure is not allowed in the home and is performed only otolaryngologist. Washing frees sinus with the sinus of the accumulated mass and purulent secretions, prevent propagation of infection and eliminate inflammation.
sources:
Vidal: https://www.vidal.ru/drugs/suprax__2432
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 8f078432-0a46-460e-90d7-03a20eba8e77 & t =
Found a bug? Select it and press Ctrl + Enter
