Often, when a particular disease is assigned a complex treatment. Many patients who have digestive disorders, interested in the question - which is better, Pariet or De-Nol. Try to understand.
Comparison of composition, mechanism of action
Preparations Pariet and De-Nol is no structural analogues. Therefore, they have many differences. Let's compare De Nol and Pariet of the main criteria.
Structure
Pariet comprises rabeprazole current component. De-Nol is composed of bismuth. Also, they contain various auxiliary components which complement the effect of the active substances.
Drug group
Both agents are drugs for treatment of diseases of the digestive tract. Pariet also referred to as proton pump inhibitors. De-Nol - antimicrobial, astringent.
release Form
Both drugs are released in the form of tablets for internal use.
Mode of application
How to drink these medicines? Here are some recommendations:
- De-Nol drink half an hour before meals. The dosage is adjusted individually. Typically, the recommended daily dose - 4 tablets;
- Pariet is recommended to take in the morning half an hour before a meal. The dosage and duration of treatment depends on the type of pathology. For example, gastric ulcer medicine drink 20 mg 1 time per day. therapy in this case is not more than a month. In severe cases, the duration of treatment can be increased up to 8 weeks.
Mechanism of action. Mechanism of action also means significantly different, as they have in the composition of different active ingredients:
- De-Nol has astringent, antibacterial, antiseptic and gastrotsitoprotektornoe action;
- Pariet has antiulcer and antisecretory action.
Indications
Both drugs are used to treat pathologies of the gastrointestinal tract. They are prescribed in peptic ulcer disease, as well as gastrointestinal diseases provoked harmful action of Helicobacter bacteria. De-Nol is also used to treat gastritis, gastroduodenitis, functional dyspepsia syndrome irritable bowel, nonsteroidal anti-inflammatory effects of poisoning medicines. Pariet is used to treat gastroesophageal disease, Zollinger-Ellison syndrome, when abnormal gipresekretsii.
Contraindications
Both tools have the same contraindications:
- idiosyncrasy components;
- severe renal disease;
- pregnancy;
- breastfeeding;
- childhood.
side effects
Both treatments were well tolerated. dyspepsia can be observed in the period of habituation, which will eventually disappear. In some cases, there are allergic reactions such as rash, redness, erythema. Chronic administration Pariet in a patient having problems with hematopoiesis.
Manufacturer and price
Pariet - a Japanese drug. Its price depends on the number of pills in a package, ranging from 950 to 3500 rubles. De-Nol is produced in the Netherlands. The cost of the drug - from 360 rubles 32 to 940 tablets 112 tablets rubles.
Preparations De Nol and Pariet are analogous to the mechanism of action. Another popular medication from this group - omeprazole. Rabeprazole - it is a structural analogue of Pariet. Assign a particular tool can only physician.
Simultaneous administration of drugs
Many patients wonder if Pariet can be taken with De nolom? Often stomach ulcer or other diseases of the gastrointestinal tract develop against bacterial infection. The causative agent is usually in favor of Helicobacter. To destroy bacteria use complex treatment with the help of De Nol, Pariet, klatsid, amoxicillin and bifiform. This therapy lasts for 10 days. Next drink while De Nol with Pariet in small doses for 3 weeks.
sources:
Vidal: https://www.vidal.ru/drugs/de-nol__6730
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7696368a-c3a6-4fd8-b73c-69a9af455d51 & t =
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