Assignment of an antibiotic for the treatment of an infectious disease occurs after detection of agent laboratory diagnostic methods. Which is better: Zinnat or Augmentin - these issues should be resolved at the reception of the expert, as antibiotics - serious medicines that should not be prescribed for themselves and their families independently.
similarities drugs
Augmentin compared with Zinnat can be on different parameters. In this article, we will rely on the pharmacological properties of the spectrum of activity, indications, contraindications, side effects, the use during pregnancy. The main similarity Zinnat Augmentin and in that both tools have antibacterial effect and can be used for the treatment of infectious pathologies.
A wide spectrum of activity and Augmentin Zinnat almost identical. Both drugs are effective against gram-positive and gram-negative aerobic and anaerobic bacteria. More information about the susceptibility of microorganisms exist in the official instructions for use.
A similar spectrum of activity makes the general indications for Augmentin and Zinnat:
- ear pathology, nose, throat, pharynx, larynx, trachea with an infectious inflammation and chosen pathogen (tonsillitis, tracheitis, laryngitis);
- lower respiratory tract infections;
- diseases of the bladder, ureters, urethra, connected with the penetration of pathogenic microorganisms;
- infectious and inflammatory skin lesions and deeply lying tissues.
Zinnat and Augmentin produced in several dosage forms: tablets, granules for the preparation of liquid suspension. The second form is widely used for the treatment of infections in children since the age of three months.
Augmentin with Zinnat have almost identical adverse effects:
- joining a fungal infection in the oral cavity;
- increasing the concentration of eosinophilic cells in the blood, signs of hemolysis of red blood cells, severe leucopenia;
- allergic reactions such as rash, accompanied by itching, serum sickness, anaphylactic shock;
- dyspepsia digestive system, intestinal pain, bloating, Clostridium-associated diarrhea;
- increase the level of enzymes cytolysis of liver cells, signs of jaundice, bile stasis and liver inflammation.
differences
Differences begin when describing pharmacological groups. Augmentin belongs to penicillin. Zinnat takes extensive class of cephalosporins of the second generation. Chemical structure causes the various mechanisms of action of antibiotics, and the activity spectrum of applications.
The second important difference - the presence of parenteral dosage forms in Zinnat. The drug may be administered by intramuscular injection, which decreases the delivery time of the active substances to target organs and improves the bioavailability of the medicament well. Both drugs have a bactericidal effect. Zinnat additionally active against gonorrhea and Borrelia, which allows the use of a means for the treatment of gonorrhea and Lyme disease. Augmentin, in turn, is widely used in the infection, accompanied by the release of bacterial beta-lactamases.
Zinnat is contraindicated during lactation. Augmentin during feeding breast milk can be used. minor side effects associated with the digestive disorder can occur in children. In the presence of strong deviations means to cancel.
Admission Zinnat Augmentin and occurs in different ways in relation to breakfast, lunch and dinner. Augmentin drink just before a meal, usually three times a day, Zinnat - after eating 2 times a day.
The possibility of simultaneous application
Simultaneously with Zinnat not take Augmentin. In such combination therapy does not make sense, because the medication is almost the same spectrum of activity. The admission of any antibiotic should be justified. The drugstore chain these drugs is forbidden to let go without a prescription. Such a policy aimed at reducing the number of resistant organisms and an increase in the effectiveness of existing drugs.
analogs
Augmentin can replace other protected penicillins (amoxicillin), macrolides (Sumamed), some cephalosporins or respiratory fluoroquinolones. Appointment analogues depends on the clinical situation. The analogue may be Zinnat cephalosporin second (cefotiam, Cefaclor), third (Supraks, cefixime, ceftriaxone) and fourth generation (Cefepime).
conclusion
When Lyme disease and gonorrhea Zinnat preferred. When the infection is accompanied by the release of beta-lactamase, Augmentin should choose. The same drug should be used, if necessary, antibiotic therapy during lactation. If the patient needs to undergo a course of parenteral drug delivery and to achieve quick results, it is better to use sequential therapy Zinnat.
For the purpose of any antibacterial drug should consult a doctor.
sources:
Vidal: https://www.vidal.ru/drugs/augmentin__96
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 181e9388-c7af-4899-a60b-cbf46ad9e251 & t =
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