Levosin: pharmacological properties
To find out what is better: Levosin or Levomekol should elaborate on each preparation. Levosin - antibacterial ointment containing the composition of several active antimicrobials: chloramphenicol, sulfonamides, Methyluracilum. Ointment manufactured by various companies in pharmaceutical vials or containers of soft aluminum.
The main pharmacological effect - anti-microbial and anti-inflammatory. Means applied to the wound surface, promotes good cleansing and removal of necrotic masses accelerates healing, the formation of a fibrin tissue. Due to the content in the composition of antibacterial components Levosin effectively combats local pathogenic flora, sensitive to the antibiotics listed above.
Pharmacokinetic parameters are associated with a feature of the dosage form. The ointment is effective only when applied topically, penetration of active ingredients in the systemic circulation is minimal. Toxic effect on the liver and kidneys excluded. Levosin recommended for use in patients who did not take chloramphenicol, sulfonamides, Methyluracilum in the next six months. Otherwise, sensitivity to the medicament may be reduced.
The main indications for use Levosin:
- Purulent wound infections;
- burns;
- Scratches, wounds of various etiologies;
- Ulcers of the lower extremities;
Spectrum contraindications to the use of:
- Wounds viral etiology;
- Increased sensitivity to antimicrobial components.
Side reactions are minimal and are associated with allergic manifestations when re-applied ointment. If signs of allergy it is recommended to replace the ointment or to see a doctor for the purpose of systemic drug action.
Levosin ointment should be applied to the skin and wound surfaces sterile material twice a day for a week. Perhaps administering ointments in the cavity through purulent drainage. In such use Levosin should be warmed to body temperature. The course of treatment can be extended under indications, but should last at least a week.
Before applying Levosin conduct primary surgical treatment of wounds, dead tissue is removed, washed defect antiseptics. After use, a sterile bandage applied ointment.
Levomekol: pharmacological properties
Compare levomekol Levosin and can be carried out on the basic parameters: pharmacological properties, pharmacokinetics, composition, indications, contraindications, side effects, applying the rules. Levomekol - similar to Levosin drug mechanism of action and effect. Ointment Levomekol - combined antibacterial agent. The spectrum of activity includes Gram-positive and -negative bacteria, including Pseudomonas aeruginosa.
Levomekol promotes regeneration of damaged tissues, eliminates bacteria, stimulates the formation of macrophages and neutrophils. The ointment is also applied topically. Absorption from the skin into the systemic circulation is minimal. Toxic effects on internal organs means causes.
Levosin differs from levomekol composition. Levomekol contains only the chloramphenicol methyluracil. Available in tubes of ointment '40 Each package levomekol present instruction manual, which lists the main indications for the use of the ointment:
- Wounds with purulent content if the selected exciter is included in the spectrum of activity of the drug;
- Acceleration of the healing of wounds and burns of various etiology;
- Treatment of inflammation of the nasal sinuses and the middle ear.
Contraindications levomekol identical contraindications to spray Levosin and include increased reaction sensitivity to components of the drug composition. Adverse reactions are rare and few as rash, hives. Since these medications are similar to the basic pharmacological properties and evidence, we can assume that Levosin analogue levomekol.
Dosing levomekol also largely similar to the application of rules Levosin. The drug is applied to the sterile material (napkins, tampons, cotton balls) and filled with this material wound. In surgical practice Levomekol can be used for administration of active substances directly into the cavity containing pus. Duration of treatment levomekol - at least a week.
Compare levomekol and Levosin
After studying the basic parameters medication easily can carry out a detailed comparison levomekol and Levosin. In general, preparations are identical. There is little difference in the composition - Levosin, in addition to common components levomekol also contains chloramphenicol. Contents chloramphenicol slightly expands levomekol spectrum activity but, nevertheless, indications for use in medicine are identical.
And Levomekol and Levosin popular among the people. Drugs have the same indications and contraindications for use, virtually no side effects, do not have any special instructions. Levomekol Levosin and can be used for disinfection of purulent cavities through drain pipes.
Levomekol and Levosin a long time used in medical practiceTherefore there is a tendency to lower the sensitivity of the bacterial flora to the components of these preparations. Micro-organisms mutate and produce new proteins become resistant to the usual antibiotics. The effect of using levomekol Levosin and usually only in those patients who have not previously used these drugs for the treatment of any purulent infections.
The ability to share applications
Usually there is no need to jointly use two antibacterial ointments with virtually identical properties. Wound surface may be lubricated simultaneously Levosin and Levomekol data medicines do not possess antagonist properties, are unidirectional, do not enhance the effects of each other. Before applying the ointment must necessarily carry primary surgical treatment of the wound. After workup and lubrication and Levosin levomekol recommended to apply a sterile dressing. Bandages should be changed at least twice a day until healing of purulent process.
As with all antibiotics, Levosin Levomekol and require compliance with the rules of admission of antimicrobials:
- The use of only prescribed by a doctor. The uncontrolled use of antimicrobials promotes the development of microbial resistance. The antibiotics are often wrongly used, the more difficult in the future to cure really serious microbial infection;
- Compliance with dosages and treatment. It is necessary to adhere strictly to therapy scheme specified in the instructions for use or told to consult a physician instructions. Under no circumstances should you cancel the antibiotic earlier than one week (for certain drugs - 3-4 days);
- Acceptance of additional agents that protect the internal organs. This paragraph does not apply to Levomekol and Levosin. When receiving systemic drugs must be used probiotics, prebiotics for normalization of intestinal microflora. If you need a reception toxic drugs, it is better to combine the use of a hepato, angi-, renoprotektorami.
conclusion
Levosin Levomekol and can be considered analogs of each other. It should be remembered that both ointments are used in medical practice, and popular for a long time and uncontrollably, so Many microorganisms developed resistance to basic substances pharmaceutical medicaments data. Not all patients have an antimicrobial effect on the application of ointments, but in any case Levosin Levomekol and promote faster healing.
Lubricate the wound with Levosin levomekol impractical because both ointments are unidirectional, do not fall into the systemic circulation, not potentiate the effect of each other. Where indicated, select any one drug, and take a full and adequate course of treatment.
sources:
Vidal: https://www.vidal.ru/drugs/levomecol__1655
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = cf36eacd-b2d6-4389-92b4-4fb0e257825f & t =
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