Ointment for psoriasis helps relieve itching and remove severe inflammation. For the treatment of skin diseases is better not to use hormonal ointments and creams with anti-inflammatory and exfoliating effects. List of ointments for psoriasis is quite extensive. Consider the most popular means of ointment, and especially their action on the skin of a human patient.
The psoriasis is treated and can be cured if it outer ointments? And how to use the ointment for psoriasis?
Which medicine to choose?
The disease is considered incurable, so no ointment can not once and for all deal with psoriasis in 2019. All drugs have only a temporary effect and helps to prolong the period of remission. In addition, treatment of the disease should be comprehensive. You must also use psychotherapy, diet pills, and exposure of the skin.
How successful will work or that the ointment, it is impossible to predict in advance. It depends on many parameters:
- type of disease,
- stage of the disease (progressive, stationary or regressing)
- seen whether the acute phase or remission,
- characteristics of the body affected by psoriasis.
Therefore, the choice of external funds for the treatment must deal with an expert dermatologist.
The pros and cons of various drugs
Particularly effective in the topical treatment of psoriasis differ ointment. They may be hormonal and non-hormonal.
Hormonal treatments provide a quick effect: they can be used for a short time to get rid of symptoms. However, use of these agents has some serious drawbacks.
Disadvantages of hormones:
- the result is short-lived;
- steroids are addictive, and you have to constantly increase the dose;
- hormonal ointments lead to complications of the disease (e.g., the development of psoriatic arthritis), and the manifestation of severe side effects of cardiovascular and endocrine systems, liver and kidney.
And the aggressive effects on the body, many experts avoid use of glucocorticosteroids, preferring to use a non-hormonal treatment for psoriasis ointment. The advantages of these funds:
- enough high efficiency;
- the absence of addiction and the subsequent cancellation of the effect;
- a small amount of side effects;
- security in terms of maintaining the hormonal balance in the body;
- accessibility in terms of price.
Hormonal ointment for psoriasis: a list of the best
A common group of external agents for the treatment of psoriasis in 2019 year is hormonal ointments based on glucocorticoid hormones.
These substances have the ability to inhibit the activity of the immune system, reducing inflammation. Therefore, when severe exacerbations psoriasis systemically administered steroids - in the form of tablets or injection. However, this approach is fraught with serious side effects of therapies: hormonal changes the body, and the removal of the drug can lead to malfunction of the endocrine and cardiovascular systems.
Most often hormonal creams and ointments are made on the basis of the following substances:
- betamethasone ( "Akriderm", "Beloderm", "Celestoderm");
- Hydrocortisone ( "hydrocortisone", "Latikort", "Oksikort");
- Clobetasol ( "Kloveyt", "Pauerkort");
- mometasone ( "Uniderm", "Elokim", "Gistan H");
- Methylprednisolone ( "Advantan", "Komfoderm);
- triamcinolone ( "ftorokort", "Triakort");
- fluocinolone ( "flutsinar", "sinaflana").
Consider the best hormonal ointment psoriasis are present on the market in 2019:
Dermoveyt
Corticosteroids for external use, acts as an anti-inflammatory agent through several mechanisms of inhibition of late phase allergic reactions, including a decrease in the density of mast cells, a decrease in chemotaxis and activation of eosinophils, a decrease in cytokine production by lymphocytes, monocytes, mast cells and eosinophils, as well as the suppression of arachidonic metabolism acid.
- Active substance: clobetasol.
- Prices in pharmacies 519 - 812 R.
The method and dosage
A preparation in the form of an ointment or cream should be applied thinly 1-2 times a day in an amount sufficient to cover the entire area affected and rubbed gently.
Dermoveyt applied until the therapeutic effect (if necessary - up to 4 weeks). If a more prolonged therapy is recommended application rate gradually decrease or go to the use of a less active formulation.
Before applying the emollient after each application of the drug is necessary to provide sufficient time for exposure Dermoveyta. In the treatment of exacerbations of skin diseases can be carried out repeated treatment courses.
Contraindications
- untreated infections of the skin;
- rosacea (rosacea);
- acne;
- perioral dermatitis;
- itchy skin in the absence of inflammation;
- perianal and genital itching;
- Children under 1 year;
- breastfeeding;
- Hypersensitivity to clobetasol or any other components included in the preparation.
Precautions: increased sensitivity to local corticosteroids or any auxiliary substance, a part of the formulation; psoriasis; child age from 1 year to 18 years.
Side effects
- Immune system: very rarely - hypersensitivity;
- General disorders: very rarely - pain and / or irritation at the site of application;
- Skin and subcutaneous tissue disorders: often - pain or burning sensation, itching; infrequently - striae, local skin atrophy, telangiectasia; very rarely - thinning, wrinkled skin, urticaria, aggravation of symptoms of the disease, dry skin, hypertrichosis, change in pigmentation, pustular psoriasis, allergic contact dermatitis, rash, erythema (many of the above cutaneous manifestations secondary to systemic and / or local effects suppression of the hypothalamic-pituitary-adrenal systems);
- Endocrine system: very rarely - inhibition of the hypothalamic-pituitary-adrenal system, signs kushingoida (for obesity central type, moon face), growth retardation and / or delay of weight gain in children, glaucoma, osteoporosis, glycosuria and / or hyperglycemia, hypertension, cataracts, obesity or weight gain, alopecia, reduction of endogenous cortisol brittle hair;
- Parasitic and infectious diseases: very rarely - infections caused by opportunistic organisms.
When applied Dermoveyta on large surfaces for a long period of time (e.g., more than 14 days), may occur in such patients systemic side effects such as: Cushing's symptoms, gastritis, increased intraocular pressure, ulceration of the mucous membranes of the gastrointestinal tract.
Reviews
According to the reviews, Dermoveyt in the form of an ointment, which is prescribed for various skin diseases, including psoriasis, exhibits high efficiency, facilitating the flow of the disease and allowing virtually eliminate external manifestations. Many patients also respond well and cream.
Akriderm GK
SCS for local use + + aminoglycoside antibiotic-antifungal agent. Combined preparation for external use with anti-inflammatory, antiallergic, antifungal (fungicidal) and antibacterial action.
- Active substance: betamethasone.
- Prices in pharmacies 420 - 600 R.
The method and dosage
The cream and ointment Akriderm recommended to apply lightly rubbing on the affected skin from 1 to 3 times a day.
The duration of treatment depends on the disease and the therapeutic effect, but should not exceed three weeks. If within two weeks of the drug is no improvement, should be put notify your doctor.
Contraindications
- lupus;
- cutaneous manifestations of syphilis;
- chicken pox;
- Herpes simplex;
- Skin reactions after vaccination;
- open wounds;
- Children under 2 years old;
- hypersensitivity to the drug.
Precautions should use the drug during pregnancy (especially in I trimester), children and adolescents aged 2 to 18 years.
Side effects
The drug may cause the following side effects:
- Burning;
- folliculitis;
- Irritation and dryness of the skin;
- hypertrichosis;
- Allergic contact dermatitis;
- hypopigmentation;
- skin atrophy;
- Prickly heat;
- The appearance of striae (stretch marks skin).
In overdose Akriderm able to inhibit the function of the pituitary-adrenal system, thereby causing the development of secondary adrenal insufficiency, as well as the appearance of Cushing's symptoms, including syndrome Cushing.
Elokim
Corticosteroids for external use. It has anti-inflammatory, antipruritic and antiekssudativnoe action. GCS induce isolation of proteins that inhibit phospholipase A2, and collectively known lipocortin which control the biosynthesis of inflammatory mediators such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.
- Active substance: mometasone.
- Prices in pharmacies 78 - 84 F
The method and dosage
Cream or ointment applied thinly to the affected skin 1 time / day.
The duration of treatment is determined by its efficacy and tolerability by the patient, presence and severity of side effects.
Contraindications
- rosacea, perioral dermatitis;
- bacterial, viral (Herpes simplex, Nerpes zoster, chickenpox), fungal infection of the skin;
- tuberculosis;
- syphilis;
- post-vaccination reactions;
- pregnancy (application on large areas of skin, long-term treatment);
- lactation (used in large doses and / or for a long time);
- hypersensitivity to the drug or corticosteroids.
The caution should be applied to the drug to the skin of the face and intertriginous skin, use occlusive dressings, and apply over large areas of the skin and / or for a long time (particularly in children).
Side effects
Local reactions: seldom - skin irritation and dryness, burning sensation, pruritus, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, accession secondary infection, skin maceration, signs of skin atrophy, striae, prickly heat; less than 1% - the formation of papules, pustules.
When applying the external forms of corticosteroids for a long time and / or for the treatment of large areas of skin, or by using occlusive dressings, especially in children and adolescents, may experience side effects typical of systemic corticosteroids, including adrenal insufficiency and Cushing's syndrome.
hydrocortisone
Glucocorticoid, anti-inflammatory and antiallergic action. Reduces inflammatory cell infiltrates, reduces migration of leukocytes, including lymphocytes in the area of inflammation. Stabilizes cellular and subcellular, including lysosomal membranes and membranes of mast cells.
Reduces the binding of immunoglobulins with receptors on cell surfaces and inhibits the synthesis or release of cytokines (interleukins and interferons) from lymphocytes and macrophages.
- Active substance: hydrocortisone.
- Prices in pharmacies 30 - 160 R.
The method and dosage
The preparation is gently rubbed into the affected areas of skin. the ointment should be applied no less to achieve the optimum effect than 2 times a day. It is recommended to rub massage movements means not strong - it will improve the absorption of the ointment.
The duration of the therapeutic course is 1-2 weeks, but depending on the state of health of the patient the physician can continue the course, or vice versa, to reduce it. If the use of the drug has no effect, then after 5-7 days of treatment is canceled.
Contraindications
- purulent, virus, tuberculosis, fungal diseases of the eye;
- glaucoma;
- trachoma;
- vaccination period;
- Break eye membranes;
- age of 18 years;
- hypersensitivity to the drug.
Side effects
Perhaps: allergic reactions, burning, injection sclera, transient blurred vision.
With prolonged use of more than 10 days can be observed:
- increased intraocular pressure possibly followed by the development of steroid glaucoma and optic nerve lesion violation of the visual fields (hence the application of preparations containing glucocorticosteroids, more than 10 days regularly measure intraocular pressure);
- posterior subcapsular cataract formation;
- slowing the healing process (in diseases that cause corneal thinning, its possible perforation).
Secondary bacterial infections can occur as a consequence of the suppression of the protective reaction of the organism of the patient. In acute purulent eye diseases glucocorticoids may mask or enhance existing infectious process.
Advantan
When applied topically Advantan suppresses inflammatory and allergic skin reactions as well as reactions associated with enhanced proliferation that It reduces the objective symptoms of inflammation (including erythema, edema, oozing, and so on. d.) and subjective sensations (including itching, irritation, pain and so on. d.).
- Active substance: methylprednisolone.
- Prices in pharmacies 537 - 1390 R.
The method and dosage
The drug is used topically. Adults and children 4 months of drug applied 1 time / day thin layer to the affected skin.
Continuous Advantan daily application in the form of a cream, ointment or fatty ointment should not exceed 12 weeks for adults, for children - 4 weeks. Advantanom course of treatment in the form of emulsions usually should not exceed 2 weeks.
Contraindications
- tuberculous or syphilitic processes in applying the product;
- viral diseases in the field of application of the drug (e.g., varicella, herpes zoster);
- rosacea, perioral dermatitis in applying the product;
- skin areas with pryavleniyami response to vaccination;
- Children up to age 4 months;
- hypersensitivity to the drug.
Side effects
Usually the drug is well tolerated.
Very rarely (less than 0.01% of the cases), local reactions can occur, such as itching, burning, erythema, vesicular rash. If the drug is used up to 4 weeks and / or the area of 10% or more of the body surface, the following reaction may occur: skin atrophy, telangiectasia, striae, akneformnye changes in the skin, systemic effects due to absorption corticosteroid. In clinical studies, none of these side effects were not observed when using the drug Advantan to 12 weeks in adults and 4 weeks in children.
In rare cases (0.01-0.1%) can be observed folliculitis, hypertrichosis, perioral dermatitis, skin depigmentation, allergic reactions to a component of the drug.
ftorokort
Corticosteroids for external use. The local application has anti-inflammatory, anti-allergic, anti-oedematous and anti-proliferative action.
- Active substance: triamcinolone.
- Prices in pharmacies 240 - 404 R.
The method and dosage
The drug is applied a thin layer to the affected areas of skin 2-3 times / day (maximum daily dose of 15 g). Perhaps the use of occlusive dressings, with a maximum amount of ointment should not exceed '10
The course of treatment - typically 5-10 days, during thrust - up to 25 days is not recommended to use more than 4 weeks.
Contraindications
- hypersensitivity to the drug;
- viral, bacterial (including tuberculosis) and fungal infections of the skin;
- trophic ulcer of the lower leg;
- acne rosacea;
- acne vulgaris;
- perioral dermatitis;
- intertrigo;
- can not be applied to the wound;
- Children under 2 years old.
Precautions: Pregnancy.
Side effect
Side effects when used externally are rare and are reversible.
Possible: burning, itching, irritation, dryness, folliculitis, hypertrichosis, akneiformnaya rash, hypopigmentation, perioral dermatitis, allergic or contact dermatitis, skin maceration, secondary infection, skin atrophy, striae, miliaria.
flutsinar
Corticosteroids for external use. It has anti-inflammatory, anti-allergic, antiekssudativnoe and antipruritic effect. reduces the appearance of or eliminates the cutaneous inflammatory reaction.
- Active substance: fluocinolone.
- Prices in pharmacies 311 - 443 R.
The method and dosage
External applied 1-3 times / day depending upon the dosage form.
Contraindications
Bacterial, viral, fungal skin diseases, lupus, skin manifestations of syphilis, extensive psoriatic lesions, anogenital pruritus, leg sores associated with varicose veins, skin tumors, pregnancy.
Side effect
Perhaps: telangiectasia, poststeroidnaya vascular purpura, skin atrophy, skin stretching, hirsutism, hypertrichosis, perioral dermatitis, secondary infections of the skin; long-term use and / or applied to the large surfaces are possible systemic side effects.
Flutsinar With prolonged use, particularly when applied ointment over a larger area of the skin may the appearance of edema, increased blood pressure, increased blood sugar levels (hyperglycemia), the development of the syndrome Cushing. flutsinar use should be discontinued immediately at the appearance of the symptoms of overdose.
Hormonal ointment for psoriasis: a list of the best
Given the serious side effects of hormonal creams and ointments, many patients prefer to treat psoriasis using less "aggressive" drugs. Some of them are the property of traditional medicine and traditional recipes for skin treatment, popular in the past.
The advantages of non-hormonal treatment of psoriasis ointment should be attributed to its relative safety of hormonal agents, cheapness and lack of serious side effects. Disadvantages - different (frequently - low) degree of efficiency and in some cases - allergic reactions which develop in patients receiving components of a particular agent.
Most often, non-hormonal creams and ointments are made on the basis of the following substances:
- Naftalan, ichthyol, dermatolovaya, kartalinovaya ointments, tar-based ointment - possess anti-inflammatory and antiseptic action.
- Keratolytics (salicylic sulfur ointment "Tsignoderm") possess anti-inflammatory and antimicrobial effect, cause enhanced exfoliation of dead skin cells, which accelerates the healing process psoriatic plaques.
- Herbal preparations (ointments and creams based on aloe, elecampane, celandine, sage and other herbs) have anti-inflammatory and healing effect, prevent the development of skin infections.
- Moisturizers (baby creams and oils, cosmetic hydrating means "Bioderma", "Vichy", "Muster" and etc.) are also supporting the treatment of psoriasis and help combat dryness and a sense of tightness skin.
We should also highlight group nonhormonal drugs whose effectiveness in the topical treatment of psoriasis confirmed in clinical trials:
- Pimecrolimus ( "Elidel" cream) has a high anti-inflammatory activity. However, be aware that in the case of bacterial or fungal infections of the skin application of funds on the basis of pimecrolimus is recommended only after treatment of the infection.
- zinc pyrithione (creams and aerosols "Tsinokap", "Skin-cap"). Due to the proven efficacy and safety, drugs for the treatment of psoriasis based on this active ingredient can be classified as assets of "golden mean."
- Calcipotriol (cream and "Dayvoneks" ointment) is a synthetic analogue of vitamin D3. Its action is based on the increase in calcium levels in skin cells that normalizes their rate of division and promotes resorption of psoriatic plaques.
Consider the best hormonal ointment psoriasis are present on the market in 2019:
Tsinokap
The drug with antiproliferative, antibacterial and antifungal Dermatoprotektorny preparation for external use. Zinc pyrithione has antiinflammatory, antibacterial and antifungal activity.
- Active substance: zinc pyrithione.
- Prices in pharmacies 320 - 939 R.
The method and dosage
Tsinokap cream applied externally, causing the affected area with a thin layer 2-3 times a day.
Aerosol Tsinokap applied externally by spraying a drug from a distance of 15 cm 2-3 times a day before application cylinder shaken. Included with the product is a nozzle designed for the treatment of scalp. Use of the drug is recommended to continue for at least 1 week after the disappearance of symptoms.
The recommended duration of treatment:
- seborrheic dermatitis - 2 weeks;
- atopic dermatitis - 3-4 weeks;
- Psoriasis - 4-6 weeks, with the aggravation of the symptoms is recommended re-treatment.
Contraindications
- Children under 1 year;
- hypersensitivity to the drug.
Side effect
Perhaps: allergic reactions. The drug is generally well tolerated.
Dayvoneks
A synthetic analogue of the most active metabolite of natural vitamin D3. It causes dose-dependent inhibition of keratinocyte proliferation (significantly elevated in patients with psoriasis) and accelerates their morphological differentiation. It had little effect on calcium metabolism in the body.
- Active substance: calcipotriol.
- Prices in pharmacies 1110 - 1520 R.
The method and dosage
Dayvoneks drugs used topically applying to the skin of the body affected areas 2 times a day, a course of treatment no more than 6-8 weeks. Usually, after 1-2 weeks of clinical effect occurs.
The maximum daily dose of solution, cream or ointment should not exceed 15 g, weekly - 100 g If necessary multiplicity applying the cream or ointment may be reduced to 1 times a day. Additionally, it is shown to be well tolerated and improves the therapeutic effect of the simultaneous application of an ointment in combination with cyclosporine and acitretin. When combined with a glucocorticosteroid (GCS) alternates the use of drugs, ointment applied morning GCS - evening.
The maximum weekly dose of the ointment in the treatment of children, the age limit from 6 to 12 years - 50 g, over 12 years - '75
Contraindications
Do not use this cream and ointment patients with diseases occurring with disorders of calcium metabolism.
Age restrictions:
- Cream: 18;
- Ointment: up to 6 years.
To use caution cream and ointment Dayvoneks acute renal and liver failure, hypercalcemia, hypervitaminosis of Vitamin D, hypercalciuria, which provides a history of nephrolithiasis and the treatment patients older than 65 years.
Side effect
In some cases: transient skin irritation; when used in doses exceeding recommended - hypercalcemia.
Elidel
Antiinflammatory agent for external use. Selective inhibitor of the synthesis and release of mediators of inflammation Pimecrolimus - makrolaktama ascomycin derivative possesses anti-inflammatory action.
- Active substance: pimecrolimus.
Prices in pharmacies 926 - 1561 R.
The method and dosage
The cream is applied to skin with a thin layer and rubbed until absorbed.
Ointment applied 2 times a day till recovery. In case of continued symptoms for more than 6 weeks, the diagnosis of atopic dermatitis needs to be clarified. If the treatment was discontinued, but there were signs of the disease again, should restart the application of the drug. Instructions on the Elidel recommended tool to soften the skin applied after the cream, and in the case of receiving water treatments - before cream.
The maximum daily dose is not because its systemic exposure is minimal. In the case of contact with mucous membranes or eyes must be washed with water.
Contraindications
- Children up to age 3 months (since the safety and efficacy of Elidel cream in children younger than 3 months has not been studied);
- Elidel cream application to skin areas affected by acute viral, bacterial or fungal infection;
- Hypersensitivity to pimecrolimus or any components of the drug
Side effects
Application of Elidel Cream 1% may cause minor transient response at the site of application, such as a feeling of heat and / or burning. With considerable severity of these reactions, patients should consult a physician.
The most frequently reported adverse events were reactions at the application site of the preparation, which occurred in 19% of patients treated with Elidel Cream 1% and 16% of patients in the control group. These reactions generally arise at an early stage of treatment, were mild / moderate and short-lived.
The frequency of side effects: very often> 10%; often - of> 1% to <10%; sometimes - from> 0.1% to <1%; rarely - from> 0.01% to <0.1%; very rare <0.01%.
Very common: burning at the application of the cream. Common: local reactions (irritation, itching and redness of the skin), skin infections (folliculitis). Sometimes: fester; worsening of the disease; Herpes simplex; dermatitis caused by the herpes simplex virus (HSV eczema); molluscum contagiosum, local reactions, such as rash, pain, paraesthesia, desquamation, dryness, swelling, skin papilloma, boils.
It reported rare cases of intolerance to alcohol in the treatment of Elidel 1% cream. In most cases, immediately after drinking alcohol developed facial flushing, rash, burning, itching or swelling.
Ointment or cream - what to choose for treatment at home?
Many of the drugs listed above are available in the form of an ointment or a cream. How to choose the most appropriate form?
- The cream has a soft texture, it is easier to apply and quickly absorbed, so that it can be applied, leaving the skin open, without using bandages and without fear of staining your clothes or hands. Typically, the cream has a pleasant smell, which is also important in the daily application.
- Ointments are more dense and greasy texture that allows the drug for a long time to be on the surface of the skin, especially if you apply it under the bandage.
- Traditionally ointment for psoriasis presents wider, but this imbalance is gradually aligned - the market appears more and more new dosage forms the form of creams, gels, and aerosols, convenient to use and especially suitable for application to the remote sites (e.g., on the scalp head).
- Unlike ointment, cream to a lesser extent an irritant, so it is suitable for application to the face surface of flexion joints, areas with increased sensitivity. Also, the ointment is not suitable for application to moist areas of affected skin with liquid discharge. Cream in this sense is more versatile.
Psoriasis - a chronic disease, so it is important for each patient to find the best medicine that combines high efficiency and minimum side effects (and preferably at the right price).
